Patrick Schimmel

Evaluating the analytical performance of direct-to-consumer gut microbiome testing services - Communications Biology Comparative analysis of DTC gut microbiome testing services reveals significant methodological variability, underscoring the need for standardized reference materials and guidelines to ensure reproduc...

Our PI, Gregor Gorkiewicz was asked to contribute to an opinion piece in @derstandard.at. read it now at: www.derstandard.at/story/300000... It concerns the quality of the "Commercial At Home MIcrobiome Tests". Read the eye-opening and concerning original paper here.
www.nature.com/articles/s42...

Thanks to @microbesplanet.bsky.social and the Austrian Science Fund FWF for the dedicated funding!

Very excited to be leading this new project with Ben Coltman (@bcoltman.bsky.social). With INFORM we look at the establishment of gut and soil microbiomes following biotherapeutic interventions through the lens of metabolic fluxes and explore if there are shared principles of community assembly!

What an inspiring few days! The 2nd CoE Microplanet Annual Meeting at Castle Schlaining hosted 95 scientists to discuss the latest in microbiome research and how these microbial communities can help build a more sustainable future. Thanks to everyone who contributed!
@fwf-at.bsky.social

🏰 Kicking off the 2nd Annual Meeting of our @fwf-at.bsky.social Cluster of Excellence @microbesplanet.bsky.social at beautiful Castle Schlaining! 🌍

Excited to share ideas 🔬, spark collaborations 🤝, and explore how microbiomes shape the health of our planet 🌱

#Microbiome #PlanetaryHealth #MicroSky

Our lab is pleased to be invited to @events.embl.org today, where a conference on the human microbiome starts. @patrickschimmel.bsky.social will be featured in Thursday morning's sessions and will present on FMT for Ulcerative Colitis and mechanism of efficacy beyond bacterial engraftment.

More to follow....
#lookingforstudents

Some big news: I’ve been awarded an ERC Advanced Grant to further explore the roles of #archaea in gut #microbiomes and beyond.
@erc.europa.eu
#ERCAdG #ARCHMETH #Microbiome #Archaea #sciencepassion

Heute ist Welt-Multiple-Sklerose-Tag! MS betrifft rund 13.500 Menschen in Österreich und gilt als „Krankheit der tausend Gesichter“. Michaela Tanja Haindl erforscht, wie sich Vitamin D in der Spätphase von MS auswirkt – ein wichtiger Schritt für die MS-Forschung!
Infos ➡ https://bit.ly/3U2niHM.

We are also looking for students in this regard! Come join our fascinating science on host-microbiome interactions, IBD treatments and the tumor microbiome! #microbiome #IBD #guthealth #cancerprevention

Fusobacterium nucleatum is enriched in invasive biofilms in colorectal cancer Fusobacterium nucleatum is an oral bacterium known to colonize colorectal tumors, where it is thought to play an important role in cancer progression. Recent advances in sequencing and phenotyping of F. nucleatum have revealed important differences at the subspecies level, but whether these differences impact the overall tumor ecology, and tumorigenesis itself, remain poorly understood. In this study, we sought to characterize Fusobacteria in the tumor microbiome of a cohort of individuals with CRC through a combination of molecular, spatial, and microbiologic analyses. We assessed for relative abundance of F. nucleatum in tumors compared to paired normal tissue, and correlated abundance with clinical and pathological features. We demonstrate striking enrichment of F. nucleatum and the recently discovered subspecies animalis clade 2 (Fna C2) specifically in colon tumors that have biofilms, highlighting the importance of complex community partnerships in the pathogenesis of this important organism. ### Competing Interest Statement C.L.S. has received research funding to Johns Hopkins University from Bristol-Myers Squibb and Janssen, and royalties from Up to Date outside the submitted work. J.R.W. reports equity ownership of Resphera Biosciences.

Our latest selection for our Journal Club: The role of Fusobacterium in Colorectal Cancer is a focus of gut microbiome research. Interesting work by Queen et al.! www.biorxiv.org/content/10.1...
Next Journal Club: 13th of May 13:00. Students of @medunigraz.at, message this channel if interested.

Enrichment of human IgA-coated bacterial vesicles in ulcerative colitis as a driver of inflammation - Nature Communications Gut microbiota contribute to the pathogenesis of ulcerative colitis (UC), but the molecular mechanisms are still unclear. Here the authors show that colonic fluid from patients with UC is enriched for...

Vesicles & inflammations in IBD! Our group (@medunigraz.at)has worked together with the group of Stefan Schild (@uni-graz.at) to characterize bacterial vesicles in our clinical cohorts. Published in @natcomms.nature.com doi.org/10.1038/s414...

Stay safe from online hate with these five tips In this era of anti-science activism, it‘s wise to take steps to protect your research and reputation in the digital realm.

All scientists, regardless of their discipline or location, are potential targets for online hate. But there are things you can do to protect yourself, and resources that can help. Nature provides five steps to get started. #Academicsky 🧪

🎁 Wetenschapsfraude als verdienmodel: de handel in nepartikelen Fraude in de wetenschap komt niet meer alleen van een individu dat in de fout gaat. Het is een verdienmodel geworden van schimmige bedrijven. Kan het fundament van de wetenschap, vertrouwen, nog gered...

Scientific fraud as a business model: the trade in fake articles [in Dutch] - Jeroen Piersma writes @fd.nl
With quotes by @deadneanderthals.bsky.social, Ben Mol, Maarten van Kampen, and myself.
#GiftLink
fd.nl/bedrijfsleve...

Meet our Lab! and follow some of its members on Bsky! @patrickschimmel.bsky.social, @kl-fil.bsky.social.

Explore Human Microbiome and Host-Microbe Co-Evolution in Health with our on-demand offering! Learn from experts in microbiome, microbiota, and host-pathogen interactions. Access it now at bit.ly/KSHumanMicro... or bit.ly/KSHostMicrob....

#KSHumanMicro25 #KSHostMicrobe25 #keystonesymposia

DNA-Spuren entschlüsseln Ernährungsgewohnheiten Darmdetektive im Einsatz: DNA-Fragmente aus Stuhlproben als wichtige Innovation für die Ernährungsforschung.

Ernährungsempfehlungen und #Darmgesundheit: Das Forschungsteam rund um @cdiener.com, @chmoei.bsky.social, @kl-fil.bsky.social und @gibbological.bsky.social hat mit MEDI eine innovative Technik entwickelt, um Ernährungsgewohnheiten aus DNA-Spuren in Stuhlproben zu analysieren

Last week, our lab was invited to talk at @keystonesymposia.bsky.social, where we talked about FMT & IBD and investigations on triggers towards healing. #gutmicrobiome #mucosalimmunity #fmt #ibd We would like to thank the organizers for a great meeting. Speaker: @patrickschimmel.bsky.social

Just started with the Keystone Symposia at #KSHostMicrobe25 in a breathtaking environment. This afternoon I will be giving a short talk about microbiome transplantation efficacy in IBD, looking beyond bacterial engraftment: work from the @gorkiewiczlab.bsky.social. Hope to see you there.

Happy to join @keystonesymposia.bsky.social for the first time for the Q8 Host-Microbe Co-Evolution in Human Health in a few weeks. Our lab @gorkiewiczlab.bsky.social will be talking about the effects of fecal microbiome transplantation at the mucosa. Lifting the veil beyond microbial engraftment.

1st anniversary of our #FWF Cluster of Excellence "Microbiomes Drive Planetary Health"! Inspiring meeting with groundbreaking ideas, especially from our diverse group of international early career researchers. Exciting research is on the horizon - stay tuned for more updates!