Thiago Carvalho

Ancient origin of an urban underground mosquito Understanding how life is adapting to urban environments represents an important challenge in evolutionary biology. In this work, we investigate a widely cited example of urban adaptation, Culex pipie...

How does life evolve to adapt to modern cities?

Out now in Science, my PhD work with @lindymcbr.bsky.social uncovers the ancient origin of the “London Underground mosquito” – one of the most iconic examples of urban adaptation.

🧵(1/n)
@science.org
www.science.org/doi/10.1126/science.ady4515

Please check out our new preprint! Using single cell analysis paired with HCR to visualize transcript localization we have identified cell and tissue-specific expression of various genes encoding tubulins, kifs, and dyneins during neural crest development!

Toll-like receptor signaling outcome is determined by the stoichiometry of the endogenous TRIFosome A previously entirely unknown mode of TLR signal transduction is elucidated.

#MysterySolved! Wellcome to the #TRIFosome! Kudos to @clarebryant.bsky.social & friends for visualizing filamentous TRIF @ Science Advances & showing that a supramolecular organizing center #SMOC is required for NfKB, not TBK1, signaling!! www.science.org/doi/10.1126/...

Tick tock tick tock

Weekend reads: The LLMs ‘willing to commit academic fraud’; ‘peer replication’ instead of review; a ‘spam filter’ for predatory journals If your week flew by — we know ours did — catch up here with what you might have missed. The week at Retraction Watch featured: Preprint server removes study attributing increased infant mortality …

Weekend reads: The LLMs ‘willing to commit academic fraud’; ‘peer replication’ instead of review; a ‘spam filter’ for predatory journals

A Mafalda Livermore foi uma nomeação que surgiu quando se falava nos corredores da CML de um acordo entre o CH (antes da desfiliação da 2ª vereadora) e Moedas. Foi bastante descarado e depois veio-se a descobrir que era namorada do vereador. A reportagem mostra com quem lidamos: gente sem escrúpulos

Europe’s right-wing populists may be personae non gratae among the political establishment back home.

But in the U.S. they are being greeted with open arms and access to the top.
🔗 www.politico.eu/article/maga...

Well this is freaking cool!

Water, Japanese paper and a vacuum cleaner — the secrets of restoring Michelangelo’s Last Judgment As the Sistine Chapel masterpiece is given a facelift, new aspects of the painter’s genius are coming to light

'A white layer of salt that has settled on the fresco’s surface over the past 32yrs (...) The salt is calcium lactate formed through the combination of lactic acid in the evaporated sweat of nearly 7mn annual visitors to the Sistine Chapel with calcium carbonate in the plaster of “The Last Judgment”

Hoje celebramos o Dia do Paleontólogo no Brasil 🇧🇷🦖

A data marca a fundação da Sociedade Brasileira de Paleontologia, que hoje completa 68 anos.

A todos os paleontólogos brasileiros, feliz Dia do Paleontólogo! ⚒️
#FossilFriday

nailed it — along with the leprosy on his neck

Sakana

Speaking of 'vibe'

www.youtube.com/watch?v=W63Y...

AI Doesn’t Reduce Work—It Intensifies It One of the promises of AI is that it can reduce workloads so employees can focus more on higher-value and more engaging tasks. But according to new research, AI tools don’t reduce work, they consisten...

Engineers increasingly found themselves coaching colleagues who were “vibe-coding” and finishing partially complete pull requests. This oversight often surfaced informally—in Slack threads or quick desk-side consultations—adding to engineers’ workloads.'
hbr.org/2026/02/ai-d...

Sim, a privatização e' sempre assim, o filet mignon. O que estranho nesta historia e' a Deloitte como "consultora" e não a Spinumviva.

Felines of antiquity raku vase in full side 1. The vase is shades of reds, browns, purples and coppers with two cat shaped handles and revealed clay on one side of the vase.

Felines of antiquity raku vase in full side 2. The vase is shades of reds, browns, purples and coppers with two cat shaped handles and revealed clay on one side of the vase.

Felines of antiquity raku vase in full with dried flowers. The vase is shades of reds, browns, purples and coppers with two cat shaped handles and revealed clay on one side of the vase.

A grey cat stands proudly on a red pillow with gold leaf design. The pillow is atop a white wooden rocking chair, the throne of said cat.

Inspired by ancient reverence for cats, I've created 'Felines of Antiquity,' a raku vase that honours their timeless, divine charm and enduring diva attitudes.

Does your cat act like a god or goddess? Mine certainly does!

Share your stories and photos below, and happy #Caturday to all!

#art #cats

"SHIT"
"FUCK"
"NO"
"FUCK"
"SHIT"
"FUCK"

A sombra de Passos Seria bom que Passos desse passos para entrar a todo o vapor na política partidária de uma forma mais transparente do que o alimento cínico do sebastianismo.

'Muitas das ideias que hoje estão encarnadas no Chega e na Iniciativa Liberal foram aplicadas pela governação de Passos, em particular a colocação como alvo da austeridade da classe média que tinha ascendido da pobreza pela acção do Estado.'

www.publico.pt/2026/03/07/o...

A glimpse of Iran, through the eyes of its artists and journalists Understanding one of the world's oldest civilizations can't be achieved through a single film or book. But recent works of literature, journalism, music and film by Iranians are a powerful starting point.

Understanding one of the world's oldest civilizations can't be achieved through a single film or book. But recent works of literature, journalism, music and film by Iranians are a powerful starting point.

Lets put a spotlight on Maria Sibylla Merian, a German naturalist and artist. She was famous for her detailed illustrations of insects and plants, and her pioneering work in entomology. 

👁️ https://www.rijksmuseum.nl/en/stories/10-things/story/maria-sibylla-merian-en

Barraqueiro e Transdev posicionam-se para a concessão das linhas suburbanas da CP A CP contratou a Deloitte para realizar estudo sobre o modelo de concessão, mas contrato não está no portal do Governo que publicita os contratos públicos.

Querem saber pq os comboios estao com problemas constantes no governo Spinumviva? A degradação dos serviços essenciais e' parte integral da estrategia de privatização

www.publico.pt/2026/03/07/e...

Grilled yellowtail collar
#Kyoto

Confocal Microscopy Optimization

Can you guess the tissue?!

#immunology #vaccines #science #graduatestudent #microscopy

Are you a researcher with an interest in #biophysics and #immunology? Join our upcoming scientific meeting on the topic of immunoengineering. You can also apply to present a poster at the meeting: royalsociety.org/science-even... @dandavis101.bsky.social @imperialsci.bsky.social

Integration of biochemical and physical cues by patrolling CD8+ T cells CD8+ T cell migration is central to host defense, enabling clonal selection, tissue infiltration, and elimination of infected cells. While chemokines guide these cells by activating Rac for F-actin polymerization, recent studies reveal a complementary mechanism through Rho activation. This pathway relies on tissue confinement, which deforms the nucleus, activates the actomyosin network, and allows CD8+ T cells to use physical cues for surveillance without external signals. In this review article, we explore how chemokine- and mechanosensing-dependent pathways guide CD8+ T cell surveillance and introduce a ‘front-’ versus ‘rear-driven’ motility model to illustrate their integration for effective tissue monitoring. Ultimately, the interplay of biochemical and physical cues ensures tissue-specific protection by T cells during homeostasis and inflammation.

Integration of biochemical and physical cues by patrolling CD8+ T cells #immunology

The last photo of third-grader Mikaeil Mirdoraghi, waving to his mom before he left for school. He was killed shortly after in the U.S./Israeli strike on a primary school in Minab.

This is such a good landscaping of the mess that this administration has created to hurt themselves in the end.

My heart bleeds…

My photo shows a Roman fresco of a brown rabbit with long ears, curled on the ground, with a rounded, soft-looking body. Its head is lowered as if nibbling at three figs placed in front of it. The figs are small and round with short stems, painted in dark reddish and bluish tones. From Pompeii. Now on display at the National Archaeological Museum in Naples.

Here’s a charming Roman fresco of a little rabbit eating figs 🐰❤️

From Pompeii, 45-79 AD.

Now at the Museo Archeologico Nazionale di Napoli. 📷 by me

#FrescoFriday
#Archaeology