@franziskaknolle
Cognitive, clinical, computational neuroscience: I study how we understand language and make decisions, and what happens in the brain if things go wrong. https://franziskaknolle.com https://www.tum.de https://www.mri.tum.de
🧠 Where do we currently stand in the search for EEG biomarkers of chronic pain?
In a new preprint we present the largest benchmark to date of modeling strategies for EEG-based chronic pain biomarkers.
📄 www.medrxiv.org/content/10.6...
Many people don't know that in early #Alzheimers, the brain is hyperconnected.
New research discovered a mechanism that triggers these extra connections and found a drug 💊 that brings the number of connections back to normal.
🔗 www.kcl.ac.uk/news/early-a...
@alzheimerssoc.bsky.social
Temporally-precise sensory encoding of predicted content, entraining motor oscillations to derive time. @akalt.bsky.social's first study out @currentbiology.bsky.social, testing parts of this idea (tinyurl.com/TiCSKaltenma...). Huge thanks @leverhulme.ac.uk ac.uk @erc.europa.eu, great work Aaron!
How does the brain decide which mental strategy to use when inferring others' beliefs?
Excited to (finally!) see my first first-author paper out @natneuro.nature.com
Summary below 🧵 #CogSci #CogNeuro
www.nature.com/articles/s41...
A timely reminder that social progress doesn’t come easy. The idea of half the population not being allowed to vote might sound bizarre now but was reality until embarrassingly recently.
🧵1/3 New paper out! Beta bursts aren't all the same and their waveform shape are functionally meaningful ! @maciekszul.bsky.social & @danclab.bsky.social👇
www.biorxiv.org/content/10.6...
Artificial intelligence-associated delusions and large language models: risks, mechanisms of delusion co-creation, and safeguarding strategies - The Lancet Psychiatry www.thelancet.com/journals/lan...
I'm just a PI, standing in front of his lab, asking them once again to please label things more specifically than "Abstract.docx" or "Grant.docx"
Well, well, well. Right-wing authoritarianism is linked to belief in the paranormal, independent of cognitive style www.psypost.org/right-wing-a...
🚨Another new one from the lab!
Cascades and convergence: Dynamic signal flow in a synapse-level brain network
We simulate sensory cascades in a bona fide biological neural network.
With Caio Seguin, Maria Grazia Puxeddu, and @misicbata.bsky.social!
journals.plos.org/complexsyste...
Data-driven profiles of psychosis stages reveal distinct and overlapping clinical, cognitive, and neuroanatomical phenotypes | medRxiv www.medrxiv.org/content/10.6...
Out now in @plos.org CB: doi.org/10.1371/jour...
Neural representations of tasks change over time, even in the absence of changes in task performance. But neurons change tuning at different rates. How does a neuron's stability relate to its interactions with the population?
#compneuro #neuroskyence
fMRI connectivity is dominated by recurring high-amplitude BOLD events (CAPs, QPPs)
But what originates these events? Many think neuromodulation is the culprit. Our new work offers a simpler take: cortico-cortical dynamics alone can generate CAP-like events! doi.org/10.1371/journal.pcbi.1013995
🧵1/n
The emergence of the language system in the toddler brain | bioRxiv www.biorxiv.org/content/10.6...
Predictive coding and oscillations underlie the optomotor response in distant insect lineages https://www.biorxiv.org/content/10.64898/2026.03.01.708750v1
🚨Preprint! “Bayesian surprise tracks the strength of perceptual insight” - Work with @lindedomingo.bsky.social & @gonzalezgarcia.bsky.social
Ever wondered what factors influence the subjective experience of suddenly understanding a previously unclear input?
Click below:
doi.org/10.64898/202...
Our paper is now out at JNeuro! www.jneurosci.org/content/earl...
How do we avoid attentional capture by salient stimuli?
We found that inversions of singleton distractor representations support attentional suppression of salient items.
Innovations and Inventions at @picowerinstitute.bsky.social Neuroblox
picower.mit.edu/innovations-...
#neuroscience
Our latest paper, “Visual language models show widespread visual deficits on neuropsychological tests”, is now out in Nature Machine Intelligence: www.nature.com/articles/s42...
Non-paywalled version:
arxiv.org/abs/2504.10786
Tweet thread below from first author @genetang.bsky.social...
"..hippocampal-prefrontal systems represent emotion concepts in a map-like way at multiple levels of abstraction.."
Map-like representations of emotion knowledge in hippocampal-prefrontal systems
by
@yumengma.bsky.social and @pkragel.bsky.social
www.nature.com/articles/s41...
Washington’s refusal to regulate AI is a corruption story. Just ask Donald Trump and Speaker Mike Johnson.
No joke: I got angry hate mail today for writing an obituary of a Black woman scientist—because the person felt she did didn’t deserve the recognition.
Which just makes me want to share it again: www.nature.com/articles/d41...
The big questions facing psychedelic science:
1. What’s the biology of psychedelic experiences?
2. Is the experience necessary for clinical benefit?
3. How do we solve expectancy+unblinding in trials?
We synthesize what we know and the big Qs in a Nature Med Review:
nature.com/articles/s41...
I’m very excited about this new work describing the specific cortical-striatal circuits that are altered in Parkinson’s Disease and that should be targeted for optimal PD treatment.
www.nature.com/articles/s41...
🚨Paper alert:
Very happy to share a new preprint investigating the stability of human-based sentence entropy measures and how well they are represented with LLM-based measures!
Spoiler alert: We still need human data!💡
Thanks to the amazing team!! 🤩
arxiv.org/abs/2602.04570
Reward as drive reduction, the return!
This opinion piece on the explanatory and unifying power of the homeostatic reinforcement learning framework is amazingly accessible, despite its technical nature, and extremely insightful 👏
www.sciencedirect.com/science/arti...
1/2
Preprint alert!!! We recorded directly from the human ventral tegmental area (VTA), the principal source of cortical dopaminergic innervation, while patients performed an instrumental learning task. 🧵👇
www.biorxiv.org/content/10.6...
🚨Special issue in Schizophrenia Bulletin on Computational markers of psychosis - From latent states to neurobiological mechanisms! Led by @cognemo.bsky.social and me!! We are still accepting submissions until April 30 (despite the date in the website 😅)
academic.oup.com/schizophreni...
If you're looking for a PhD and you're interested in the cerebellum, predictions, language, and MEG, please apply by 1st March! We have two open positions.
More details here:
benediktzoefel.wixsite.com/home/phd
