Rudnicki Lab

John Saber, a PhD candidate from our lab recently and successfully defended his thesis at the University of Ottawa 🎉

Congratulations on this amazing achievement! He did an amazing job in the lab and in his project. 🧫🔬🧬

Intrinsic Muscle Stem Cell Dysfunction Contributes to Impaired Regeneration in the mdx Mouse Background Duchenne muscular dystrophy (DMD) is a devastating disease characterized by progressive muscle wasting that leads to diminished lifespan. In addition to the inherent weakness of dystrophi...

Ending this year the best way ✨️

🚨PUBLICATION ALERT🚨

"Intrinsic muscle stem cell dysfunction contributes to impaired regeneration in the mdx mouse, Marie Esper et al."
onlinelibrary.wiley.com/doi/10.1002/...

Wnt7a is required for regeneration of dystrophic skeletal muscle - Skeletal Muscle Intramuscular injection of Wnt7a has been shown to accelerate and augment skeletal muscle regeneration and to ameliorate dystrophic progression in mdx muscle, a model for Duchenne muscular dystrophy (...

December is filled with exciting news! 🔬
🚨PUBLICATION ALERT🚨
"Wnt7a is required for regeneration of dystrophic skeletal muscle by Uxia Gurriaran-Rodriguez et al."

skeletalmusclejournal.biomedcentral.com/articles/10....

Identification of the Wnt signal peptide that directs secretion on extracellular vesicles A signal peptide that directs Wnt secretion on EVs was identified, and the structural mechanism for this secretion elucidated.

🚨PUBLICATION ALERT🚨

Newest paper from our lab 🎉: "Identification of the Wnt signal peptide that directs secretion on extracellular vesicles by Uxia Gurriaran-Rodriguez et al."

www.science.org/doi/10.1126/...

Satellos Announces First Participant with Duchenne Muscular Dystrophy Dosed in the Phase 1b Clinical Trial of SAT-3247 Satellos Bioscience Inc. (TSX: MSCL, OTCQB: MSCLF) (“Satellos” or the “Company”), a public biotech company developing new small molecule therapeutic a

An incredible achievement! 💊

www.businesswire.com/news/home/20...

Picture of the Rudnicki lab at their holiday lab lunch

❄️ Rudnicki lab holiday lunch 2024 ❄️☃️

An Ottawa scientist's discovery offers rare hope for patients with devastating genetic disease An Ottawa stem cell researcher's groundbreaking discovery offers rare hope for patients with the genetic disease.

Hot off the press!🔬
Many years of research in our lab have paved the way for a possible treatment of Duchenne Muscular Dystrophy.
ottawacitizen.com/news/local-n...