Warm congratulations to The Brain Prize winners 2026, Professor David Ginty and Professor Patrik Ernfors, for their pioneering work on how the nervous system detects and processes touch and pain.
Karolinska Institutet
HHMI
#Neuroscience #BrainPrize2026
A beautiful 😍 review on vertebrate organ evolution - from molecular basis and evolutionary forces to the emergence of novel forms and functions.
Hi Angelo, should work ... but also try this one:
www.sciencedirect.com/science/chap...
It was a wonderful opportunity to reflect on our work on the development of the mammalian cerebellum.
We thank our editors, Alexandra Joyner and James Li!
Special thanks to Henrik @kaessmannlab.bsky.social for his unwavering support and mentorship!
How have concerted and mosaic evolutionary mechanisms shaped the expansion of the human cerebellum?
Our review with @tyamadat.bsky.social and @ioansarr.bsky.social available free till March 29:
authors.elsevier.com/a/1ma2wFzn7a...
Ramsey Najm and I have a joint postdoc position advertised through the @hlsalliance.bsky.social Interinstitutional Postdoc call! Our project proposes to generate better posterior cerebellar organoids to improve fidelity of pediatric medulloblastoma models.
www.health-life-sciences.de/opportunitie...
Hiring a PhD student! 🎓
Looking for a PhD student to work on the prediction of complex diseases by integrating genetics, multi-omics, and electronic health records. Details: genomics.ut.ee/sites/defaul...
Please share with anyone interested!
Some friends and I wrote a review with @biologists.bsky.social !! Together with Esther Becker and Simone Mayer, we explore the state of the cerebellum organoid field and offer practical guidance on getting this model system started in your own lab. journals.biologists.com/dmm/article/...
Congrats to @urmovosa.bsky.social and the international research team behind this achievement, including colleagues at @estbiobank.bsky.social!
Thank you!
I've started my own lab 🎉
PhD/postdoc positions available - reach out if curious about cerebellum evo-devo and autism spectrum disorders.
We’re based at Uni Tartu, Institute of Genomics (home to Estonian Biobank), and funded by @simonsfoundation.org @embo.org, and the Estonian Research Council.
This paper marks the end of a long but rewarding project - and the start of something new (more below👇).
Massive thanks to @kaessmannlab.bsky.social, @ioansarr.bsky.social, @tyamadat.bsky.social, our amazing collaborators @steinaerts.bsky.social, Stefan Pfister, Rüdiger Behr and the entire team! 💙
Big congrats to @kmatlik.bsky.social and all the EMBO Installation Grantees 2026! 👏🎉
TF-MINDI is out! A new method to learn cis-regulatory codes through rich embeddings of TF binding sites. TF-MINDI decomposes motif neighbourhoods, and works downstream of any sequence-to-function deep learning model. We deeply study the enhancer code in human neural development, check out the thread
We are looking for a Postdoc at the Center for Gene Expression in Copenhagen. Deadline for applications is the 11th of January. If you are interested in 3D chromatin, SMC complexes, and super-resolution microscopy, join us. www.nature.com/naturecareer...
Really happy to join NeuroPSI at Paris Saclay to lead a research group funded by an ERC Consolidator grant #ERCCoG . We'll study the origins of the vertebrate brain using shark embryos. 🦈 🧠 Reach out if you are interested in joining the team 🤍
Join us at SMBE26! We are in a golden period for understanding the evolution of gene regulation.
Aged mice and human samples show patterned loss of Purkinje cells in the cerebellum, revealing a spatial signature of ageing that may help explain why motor coordination and behaviour decline over time.
In 2018, Tomasz Nowakowski received our Fellows-to-Faculty Award to jumpstart his new lab. We spoke with him about his research and the Fellows-to-Faculty program, which is open for apps: https://www.simonsfoundation.org/fellows-to-faculty-alum-tomasz-nowakowski-studies-human-cortical-development/
#ERCCogG granted!!! Immensely grateful for this opportunity. Thanks @erc.europa.eu . Many news coming soon. New lab opening and will be posting positions. 🦈🧠🤍 Go sharkies!
We tend to think of neurons as either excitatory or inhibitory, but some neurons chemically inhibit their downstream targets while electrically exciting their neighbors. What is gained by having an inhibitory neuron excite its neighbor?
www.biorxiv.org/content/10.6...
JASPAR 2026 is out 🎉
The new release massively expands the TF motif collections and adds a dedicated DeepLearning collection of motifs learned from deep learning models.
Database: jaspar.elixir.no
Paper (NAR): doi.org/10.1093/nar/...
🧵1/2
Claudia Feng's Ph.D work is now out, co-led with @brittavelten.bsky.social and @steglelab.bsky.social . Large-scale CRISPRi perturbations in genetically heterogenous iPSC lines, with single cell readout - enjoy :)
Deadline approaching for participating in the international Stanford Course on Neural Assembloids in spring 2026!
This is an immersive, hands-on course on generating, probing and manipulating stem cell-derived neural #assembloids and #organoids for disease and development modeling.
Yes, this is where you would work (the round building, not the boat)
We are looking for a postdoc to join our team! If you're interested in translating a cutting edge genomics technology (www.nature.com/articles/s41...) to real-life applications in hematology, this is for you. We offer a unique working environment ON THE BEACH: recruitment.crg.eu/content/jobs...
NEW pub in @science.org 🥳
Is it sponges (panels A & B) or comb jellies (C & D) that root the animal tree of life?
For over 15 years, #phylogenomic studies have been divided.
We provide new evidence suggesting that...
🔗: www.science.org/doi/10.1126/...
Interested in applying for our Fellows-to-Faculty Award? Watch the recording of our informational webinar for more details on the program: https://www.simonsfoundation.org/grant/fellows-to-faculty-award/#:~:text=Brain%20(SCPAB).-,Informational%20Webinar,-An%20informational%20webinar #science
Our intelligence and cognitive abilities are perhaps due to an expansion of our cerebral cortex. But surprisingly, compared to highly intelligent birds, primates have many more neurons in their cerebellum as compared to the cerebral cortex.
doi.org/10.1073/pnas...
Share this funding opportunity! We offer the Fellows-to-Faculty program to nurture new talent in the basic sciences and to broaden the community of scientists contributing to Simons Foundation Autism Research Initiative (SFARI) and Simons Collaboration on Plasticity and the Aging Brain (SCPAB).
