Mohannad Dardiry

Final version @nature.com of our paper describing unconventional multicellular development in a choanoflagellate inhabiting an extreme environment. A ton of new data since the first @biorxivpreprint.bsky.social preprint (which we've kept updating).

A brief 🧵 (carried over from the old place)

Beautiful work! Congrats to all authors!

Genomic Perplexity and the Evolution of Context-Dependent Function Abstract. The fundamental principle that selection acts on a gene’s function often assumes implicitly that this function is fixed and intrinsic. However, e

New paper out in MBE! 🧵
"Genomic Perplexity and the Evolution of Context-Dependent Function"
The big idea: genes don't have fixed functions. Function emerges from context - genomic, cellular, environmental. And we can quantify this. academic.oup.com/mbe/article/...

Beautiful work by a good friend! Congrats, Jim and all the authors!

Congratulations! beautiful work!

Congrats to all authors! beautiful work Jim!

A glance back!

“The usefulness of useless knowledge” was the topic of a thought-provoking session at #NobelWeek Dialogue 2025 with laureates - hear Sir Paul Nurse and Frances Arnold from 1’19’:
📺 www.youtube.com/watch?v=urLM...

ERC grantee Jean Tirole took part in other interesting sessions.

Our Special Issue on Lifelong Development #LifelongDevSI is now complete!

Guest edited by Meri Huch and Mansi Srivastava, it contains 26 research and review-type articles.

On the cover: the dorsal vasculature of an adult zebrafish's first gill arch. See Preußner et al. doi.org/10.1242/dev....

This work also builds on my previous research, where I aim to understand the role of plasticity in evolution and how factors such as plasticity, noise, and robustness contribute to biological diversity and developmental decisions (7).

I hope this piece adds value to our understanding of plasticity, regeneration, non-bilaterians, evolution & development (6)

I would like to thank Aissam for writing this piece together. I also want to acknowledge William, the intern with whom I work closely; his contributions allowed us to advance the practical aspects of our research in parallel with our conceptual developments (5)

We propose using modularity as a framework to dissect these lifelong developmental processes. This approach encourages a conceptual shift from viewing development as a terminal process to seeing it as dynamic navigation through stable, yet responsive, organismal states (4)

Our manuscript suggests that lifelong developmental processes, such as whole-body regeneration, asexual reproduction, morphological plasticity, and reverse development, can be understood collectively through the lens of phenotypic plasticity (3).

While many animals retain the ability to transform their form and function throughout their lives, known as lifelong development, developmental biology has primarily focused on early life stages(2).

It was my pleasure to work on this piece with @aikmi.bsky.social. I enjoyed it and genuinely appreciate his way of articulating thoughts. Here, we suggest that lifelong developmental processes can be understood comprehensively through the lens of phenotypic plasticity and modularity (1).