Diego Alzate

Really excited to share our new preprint, now available in bioRxiv

www.biorxiv.org/content/10.6...

We generated vascular-like cells with a great therapeutic potential for Alzheimer's Disease.

A big thank you to everyone involved. This has been an amazing collaborative effort!!

Engrams Frankland et al. provide a history of research on engrams and their relationship to memory processes, highlighting new technologies that have allowed careful dissection of engrams and their function.

I like this one 😜

Certainly my lab is not perfectly run, but perhaps my tips for management of an academic lab can help you!

What are your tips?

Of course its music themed because consistency is my first tip!

Grants: x.com/AinslieLab/s...
Pre-interviews: x.com/AinslieLab/s...
Well-being: x.com/AinslieLab/s...

Why you are not allowed to say that your 95% confidence interval contains the true parameter with a probability of 95% A shibboleth is a custom, such as a choice of phrasing, that distinguishes one group of people from another. The term goes back to the Hebrew Bible, in which the inhabitants of Gilead identify members...

New post on the 100% Christmas Interval -- after almost 8 years, it's time that we finally talk about CIs.

www.the100.ci/2024/12/05/w...

OK If we are moving to Bluesky I am rescuing my favourite ever twitter thread (Jan 2019).

The renamed:

Bluesky-sized history of neuroscience (biased by my interests)

December is here & we're granting wishes!!! We're super pumped to be hosting @nabalabuic.bsky.social for a talk on The Matrisome project plus - a special surprise just for The Meshwork community - a demo of MatriTools! Chair: @collagenyoshi.bsky.social
Register now: forms.gle/7x3q7AfPNp38...

How the Web of Science takes a step back <p>The Web of Science, a major commercial indexing service of scientific journals operated by Clarivate, recently decided to remove eLife from its Science Citation Index Expanded (SCIE). eLife will on...

Great blog by Bodo Stern (@hhmi.bsky.social) about the recent Clarivate decision on @elife.bsky.social’s impact factor. www.coalition-s.org/blog/how-the...

Greenberg (2009) is one of my favourite papers, showing “conversion of hypothesis to fact through citation alone” and jarring citation bias in grant proposals.

Just struck me that it’s about a literature on beta amyloid—not in Alzheimer’s, but maybe still affected by the awfulness of that research?

The reproducibility crisis and other problems in science | John Ioannidis YouTube video by The Institute of Art and Ideas

The reproducibilty crisis and other problems in science. A great talk:

youtu.be/vY9mGJQFdyE?...

‘Huge influx’ of neuroscientists migrates to Bluesky Daily neuroscience-related posts on the social-media platform this week have increased more than 400 percent, on average, compared with October.

The neuroscientists are in the house! www.thetransmitter.org/community/hu...

If you had to cite an event that opened the "replication crisis" era, what would you point to?

Cancer-associated fibroblast subtypes modulate the tumor-immune microenvironment and are associated with skin cancer malignancy - Nature Communications Fibroblast heterogeneity in the tumor microenvironment can explain their multifaceted role in cancer. Here by single-cell transcriptomic analysis of basal cell carcinoma, squamous cell carcinoma and m...

Cancer-associated fibroblast subtypes modulate the tumor-immune microenvironment and are associated with skin cancer malignancy
www.nature.com/articles/s41...