Fahri Küçükali

Happy and honoured to receive the Fabrizio Caielli Award from the Carlo Besta Neurological Institute for our recent publication, “Multiomic analyses direct hypotheses for Creutzfeldt-Jakob disease risk genes” 🧠🧬

Many thanks to the selection committee for this recognition.

🔗 tinyurl.com/5y7nwp34

Extremely thankful to have our Senior Research Project (with Julie van der Zee and @verwilt.bsky.social) funded in this @fwovlaanderen.bsky.social call! This marks a huge investment into our 1000 Healthy Elderly study in search of novel cell-free biomarkers! 🧠🧬🩸

Join us! 🧠🧬

Postdoctoral Researcher in Computational Genomics of Alzheimers Disease - VIB Description TheSleegers labat the VIB-UAntwerp Center for Molecular Neurology Belgium, is seeking a highly motivated and talented postdoctoral r

HIRING ALERT!!! 💥

We are looking for an enthusiastic postdoctoral researcher to uncover Alzheimer's disease mechanisms using state-of-the-art technologies! 🧠🧬

jobs.vib.be/j/128109/pos...

Last Friday, we shared our research with 1st year Master's students at @uantwerpen.be during the Research Day! We loved their genuine interest and look forward to welcoming several of them to our lab next year.

Great to see Ph.D. students Kato and Ella share their love for science! 🧪

Consensus meta-analysis of genome-wide association studies for Alzheimer's disease and related dementia https://www.medrxiv.org/content/10.1101/2025.10.20.25338060v1

The European Alzheimer & Dementia Biobank (EADB) unites cohorts across 18 countries to decode the genetics of Alzheimer’s disease. https://eadb.eu/
At CMN, the @sleegerslab.bsky.social plays a leading role, with postdoc Fahri Küçükali as our in-house EADB specialist.

#CMNcohorts #CMNconsortia

1 year of 1000 Healthy Elderly Study! As we are closing in on 200 re-inclusions, we took some time to celebrate this amazing milestone. Find more about our study here: bit.ly/4gV9TLk

One year in, nearly 200 re-inclusions and a clearer picture of healthy brain aging!

The 1000 Healthy Elderly Study has become a real engine for discovery.

Thanks to all of our volunteers and a special shout-out to Sofie Van de kerckhoven for the excellence at intake and sampling! bit.ly/4gV9TLk

Joint PhD position on developing genetic risk scores as biomarkers for neurological disorders - VIB The Rademakers team and the Sleegers team at the VIB-UAntwerp Center for Molecular Neurology, Belgium a

🚨 #PhD opportunity! Sleegers & Rademakers Labs are looking for a PhD candidate to develop biomarkers for neurological disorders by integrating genomics & transcriptomics data🧠🔬

@cmn-vib.bsky.social 📍 Antwerp, Belgium | 💡 Genetics • Bioinformatics • Neuroscience

Apply 👉 jobs.vib.be/j/124544/joi...

Join us for this great collaborative PhD project! 😊

Next up in our #CMNcohorts #CMNconsortia series, we spotlight a collaboration between the @sleegerslab.bsky.social and Dietmar Thal at KU Leuven: a post-mortem brain cohort, now paired with genetic characterization, and transcriptomic profiling underway.

Over the moon to be selected for the Flemish #PhDCup 2025 for my research at @ugent-fge.bsky.social at the OncoRNALab with @jvdesomp.bsky.social and Pieter Mestdagh! @fwovlaanderen.bsky.social

Our postdoc @verwilt.bsky.social is selected for the @scimingo.bsky.social PhD Cup for his research during his PhD! 💥 Let's see how his findings can impact Alzheimer's Disease 🧠🧬🩸

@fwovlaanderen.bsky.social @ugent-fge.bsky.social @cmn-vib.bsky.social @viblifesciences.bsky.social @uantwerpen.be

Big congrats to @verwilt.bsky.social‬ from the @sleegerslab.bsky.social‬ on his FWO fellowship! He’ll be mapping RNA and DNA in blood, CSF, even tear fluid, to develop non-invasive biomarkers for Alzheimer’s using long-read sequencing. https://tinyurl.com/ym6c8csr

Realizing the promise of genome-wide association studies for effector gene prediction - Nature Genetics This Perspective argues that predicting effector genes for complex diseases is a key outcome of genetic association studies where standards are urgently needed to maximize utility, improve interoperab...

🚨Interested in which genes are the true effectors behind the scenes of the #gwas results? 🚨
This new publication in Nature Genetics, a collaboration between @broadinstitute.org @ebi.embl.org @opentargets.org focuses on approaches to predicted effector gene reporting tinyurl.com/98yxy4hf (1/3) 👇

Hi #eshg2025!

I’ll be giving the final presentation today on our recent work mapping Alzheimer's disease genetic risk to brain cell-type-specific transcript alterations 🧬🧠

Looking forward to it—see you there! 😄

Ciao Milano! We are happy and excited to be here for #eshg2025 @eshg.bsky.social

Come find us during the oral and poster presentations by our team members Fahri Küçükali (@maegsul.bsky.social) & Celeste Laureyssen (@celestelaureyssen.bsky.social) today and tomorrow 🧬 🧠

Look at us! 🤩 We presented the excuting research going on in our lab at the @uantwerpen.be NeuroDay 2025. So great to with fellow neuroscientist! 🧠

A new chapter in our lab has begun! Our postdoc @verwilt.bsky.social has received an FWO Junior Fellowship to look for non-invasive extracellular biomarkers for Alzheimer’s disease. Stay tuned for some cool research! @fwovlaanderen.bsky.social

YOU MUST BE KIDDING ME! 🥳 Extremely happy to be selected as a Junior FWO Postdoctoral fellowship! Stay tuned for novel extracellular biomarkers for Alzheimer’s disease! Can’t wait to jump in these three years! 🧠🩸🧬 #fwo #RNA #cfDNA #alzheimers @fwovlaanderen.bsky.social @sleegerslab.bsky.social

Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing - Nature Communications Here the authors identify TNIP1 as a risk factor for a fatal neurodegenerative disorder and discover specific genetic loci associated with the three main subtypes of this disorder. The findings highli...

Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing

www.nature.com/articles/s41...

Our lab’s recent hackathon ☕🧠💻 was a success: three packed days, one awesome crew, endless ideas. We built fresh neurogenomics tools and leveled-up team vibes 🚀🧬

🚨 PhD Position Alert! 🚨
We're excited to announce a collaborative PhD opportunity with @uantwerpen.be LEMP, investigating the role of mucin splicing in colorectal cancer. If you're passionate about RNA biology, omics, and translational research, this could be the perfect fit!

Rare, but not alone. Today, we light up for #RareDiseaseDay. We recognize the strength of those living with rare diseases and the science that seeks to understand, diagnose, and treat them. #PatientsFirst 🧬 💙

Multiomic analyses direct hypotheses for Creutzfeldt-Jakob disease risk genes Küçükali & Hill et al. integrate GWAS data with transcriptome and proteome-wide association studies to better understand risk factors for sporadic Creu

Exciting news! Our paper on GWAS gene prioritization for Creutzfeldt-Jakob Disease is now published in Brain! 🧠🧬 @brain1878.bsky.social

We leverage eQTL and pQTL catalogues to identify prioritized risk genes with potential roles in prion disease.

Check it out here: academic.oup.com/brain/advanc...

Multiomic analyses direct hypotheses for Creutzfeldt-Jakob disease risk genes Küçükali & Hill et al. integrate GWAS data with transcriptome and proteome-wide association studies to better understand risk factors for sporadic Creu

New paper on risk genes for sporadic CJD academic.oup.com/brain/advanc...

Very happy to see our review on Alzheimer's disease rare genetic variants published in @natrevneurol.bsky.social! 🧠🧬

Huge congrats to our PhD student @laradedeyn.bsky.social 🎉👏✨

www.nature.com/articles/s41...

New online! The impact of rare genetic variants on Alzheimer disease https://bit.ly/4hntQtT

🚨 New Review Alert! 🚨 Excited to share our latest in Nature Reviews Neurology! 🧠✨ We explore the impact of rare genetic risk variants on Alzheimer's disease, shedding light on key insights from recent studies.
Thank you for this opportunity!
#Alzheimers #variants #Review #rarevariant #genetics