Katerina Kraft

Genetic elements promote retention of extrachromosomal DNA in cancer cells - Nature A combination of genome-wide functional screening, imaging and chromatin profiling identifies a new class of highly prevalent genomic elements that help retain extrachromosomal DNA copies in dividing ...

Our paper is out in @nature.com! Oncogenes are often copy-number amplified on extrachromosomal DNA (ecDNA) in cancer, but how is ecDNA inherited by dividing cells? Here we identified elements within ecDNA that promote its retention in dividing cells. 1/11
www.nature.com/articles/s41...

Three new research groups joining the MPIMG

We are excited to welcome @fueyoraquel.bsky.social, @sedonamurphy.bsky.social, and @jmstein.bsky.social as new group leaders at our institute!
Read more about their work:
--> www.molgen.mpg.de/2025-10-31-n...
All three are recruiting in the IMPRS PhD Call!
--> www.molgen.mpg.de/IMPRSPhDproj...

I was lucky to share coffee corner with you in Chang lab! Does Jones lab has already coffee machine and long read sequencer? Two important devices

I recommend joining Jones lab

Looking forward, I am launching my lab in the @mitkochinstitute.bsky.social and IMES at @mit.edu, and will continue studying how the unique regulatory landscape of ecDNA enables tumor evolution. We're looking for creative scientists to push this frontier - if you're interested, get in touch!

My new lab at the @molgen.mpg.de will be following up on some of the nuclear organization aspects of ecDNA so please do reach out if this is of interest :)

I recommend joining Sedonas lab!

Our publication is out today!Big Thanks go to my amazing collaborators: @sedonamurphy.bsky.social for her imaging brilliance and @mattjones.bsky.social for his computational support.They both saw the potential in this project and helped me to explore what turned out to be an exciting discovery.

Enhancer activation from transposable elements in extrachromosomal DNA - Nature Cell Biology Kraft, Murphy, Jones et al. identify extrachromosomal DNA (ecDNA)-interacting elements (EIEs) enriched for transposable elements within ecDNA in colorectal cancer cells. They show that EIE 14 integrat...

Here, we show that the unique regulatory landscape of ecDNA enables an ancient LINE to resurrect and act as an enhancer of Myc. This was so fun with @katerinakraft.bsky.social and @mattjones.bsky.social and others. www.nature.com/articles/s41...

Coming out is not a one-time event - Nature Cell Biology June is the month celebrating Pride in the USA and other countries around the world to honour the Stonewall Uprising of 1969, as well as all progress and current strives claiming equal justice for mem...

🏳️‍🌈Our editor @slefkopoulos.bsky.social discussed with @jzylicz.bsky.social about the importance of celebrating Pride, representation in science, and more! Happy Pride!
Read here: rdcu.be/ewfba
bit.ly/3Uc72TO

Congratulations @julianeg.bsky.social 🎉 transposable elements + limb development = great story! Looking forward to many more cool papers from new Glaser lab

Congratulations team! This is cool and raises many new questions. Are there Rex diseases? How many of these elements we don’t know yet? Will there be a T rex element? And many more

Congratulations!

Thank you dear organizer and everyone for this amazing conference, such great science, intense discussions, food and wine! never attended all presentations before but this time everything was so interesting. Great dance moves as well :) And enhancer-promoter kissing concept - the topic of the year