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Jane Hawkey

@yekwah

Microbial genomics - bacterial evolution, AMR, mobile elements, phylogenetics. Located at Monash University/Alfred Hospital

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15.09.2023
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Latest posts by Jane Hawkey @yekwah

Overview β€” AllTheBacteria documentation

Courtesy of @martibartfast.bsky.social , we have a new release of AllTheBacteria which adds another 322,920 assemblies, covering all ENA (illumina, isolate) prokaryotes to May 2025.
allthebacteria.readthedocs.io/en/latest/ov...

26.02.2026 15:48 πŸ‘ 60 πŸ” 28 πŸ’¬ 0 πŸ“Œ 3
Research Assistant - Tonkin-Hill Lab Research Assistant - Tonkin-Hill Lab

It's a bit last minute, but we have an RA/junior postdoc position available in my lab (closing Sunday). Please reach out if you're interested in developing and applying methods to analyse microbial genomes and metagenomes! careers.petermac.org/job/MELBOURN...

20.02.2026 00:16 πŸ‘ 5 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0
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Registration - EMBO Workshop Shigella: from biology to prevention EMBO Workshop Shigella: from biology to prevention

To make sure the whole Shigella community will be gathered at this inaugural meeting, we have re-opened abstract submission for poster presentation until the end of the month. Please RT!
www.shigella2026.conferences-pasteur.org/registration...

12.02.2026 14:05 πŸ‘ 1 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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Spotted on the Chappell Roan merch store. I don’t think they know what Shigella is… what am I missing???

12.02.2026 11:26 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Exploring the IS-capades of Klebsiella pneumoniae: insertion sequences drive metabolic loss in obscure sub-lineages Introduction. Klebsiella pneumoniae is an opportunistic pathogen that causes a wide spectrum of infections within healthcare settings and the community. Four K. pneumoniae sub-lineages, defined using ...

Our new paper on Insertion Sequences (IS) in #Klebsiella

- Lineages have vastly different IS loads and profiles
- An inverse relationship between IS load and metabolic capacity, in particular phosphorus use, consistent with early reductive evolution.

www.microbiologyresearch.org/content/jour...

22.01.2026 19:52 πŸ‘ 30 πŸ” 16 πŸ’¬ 0 πŸ“Œ 0
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Finally got my #triplej #hottest100 votes in! Thought I heard no new music this year but that was a lie, my short list was huge. Ur A Rat and Keith I can never get out of my head

06.01.2026 10:30 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
The rise and global spread of IMP carbapenemases (1996-2023): a genomic epidemiology study - Nature Communications Carbapenemase blaIMP genes between 1996-2023 were analysed across 4,556 genomes, revealing variant-specific epidemiologies and endemicities. Horizontal gene transfer enabled broad inter-species transm...

(1/7) Really pleased to have this published in @natcomms.nature.com

We looked at all public genomes encoding blaIMP (carbapenem #AMR ) πŸ¦ πŸ§«πŸ§¬πŸ’Š. We show 5 IMP variants achieved global endemicity while 2 are regionally endemic.

www.nature.com/articles/s41...

#MicroSky #microbiology #IDSky #EpiSky πŸ§ͺ

17.12.2025 04:29 πŸ‘ 22 πŸ” 10 πŸ’¬ 3 πŸ“Œ 0
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A metabolic atlas of the Klebsiella pneumoniae species complex reveals lineage-specific metabolism and capacity for intra-species co-operation Why are there so many co-circulating Klebsiella pneumoniae clones? Using genomics and large-scale metabolic modelling of >7000 isolates, this study identifies structured, clone-specific metabolic spec...

Absolutely stoked to have this published in @plosbiology.org

We looked at the metabolism of #Klebsiella pneumoniae 🦠🧫. We not only demonstrated lineage-specific #metabolism, but that lineages can cross-feed and support each other.

journals.plos.org/plosbiology/...

#MicroSky #microbiology 🧬 πŸ§ͺ πŸ’Š

13.12.2025 09:45 πŸ‘ 82 πŸ” 32 πŸ’¬ 4 πŸ“Œ 2
GTDB - skani calculator An interface to compute pairwise ANI of NCBI genomes using the GTDB taxonomy.

The GTDB website now has an ANI calculator based on skani that supports uploading of user genomes. Try it at gtdb.ecogenomic.org/tools/skani.

Find more information about @jimshaw.bsky.social fantastic tool at www.nature.com/articles/s41....

11.12.2025 14:59 πŸ‘ 42 πŸ” 24 πŸ’¬ 0 πŸ“Œ 0

A new tool we’ve developed to identify AMR-associated SNPs in short- and long-read metagenome data….allows a greater understanding of the total resistome of a sample

08.12.2025 10:51 πŸ‘ 9 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

I’m so jelly I missed it! Any plans to make some of the materials available?

28.11.2025 11:45 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

I’ve been enjoying seeing the updates, wishing I’d made the trek to Adelaide now!

25.11.2025 04:26 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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I can’t explain why but reading the news feels like this at the moment

13.11.2025 07:02 πŸ‘ 35 πŸ” 6 πŸ’¬ 1 πŸ“Œ 0

Very interesting to see what amendments were pushed by different parties for this bit of legislation. The One Nation amendment to remove a focus on public health issues caused by climate change (thankfully voted down) was typically πŸ™„

06.11.2025 04:50 πŸ‘ 3 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
Microbial genomics for antimicrobial resistance ecology and action Nature Reviews Genetics, Published online: 03 November 2025; doi:10.1038/s41576-025-00909-zMicrobial genomics can improve our understanding of antimicrobial resistance dynamics across ecosystems. In this Comment, Kathryn Holt emphasizes the interconnectedness of human, animal and environmental health and calls for greater integration of microbial genomic data through robust analytical frameworks to unravel the complexity of antimicrobial resistance dynamics.

New online! Microbial genomics for antimicrobial resistance ecology and action

03.11.2025 13:07 πŸ‘ 14 πŸ” 7 πŸ’¬ 0 πŸ“Œ 1
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Are you hungry for some Shigella news? Why not come to the 1st International Shigella meeting www.shigella2026.conferences-pasteur.org/home 20-24 April 2026 Paris

29.10.2025 18:29 πŸ‘ 39 πŸ” 3 πŸ’¬ 3 πŸ“Œ 2
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How to rapidly search the world’s microbial DNA By making the world’s microbial DNA easier to explore, LexicMap helps researchers track outbreaks, study antibiotic resistance, and understand microbial diversity.

There are millions of openly available microbial genomes, but searching them can be slow.

Until now πŸ₯

Introducing LexicMap, a new alignment tool that lets scientists search these data in minutes, helping track antibiotic resistance, trace outbreaks, and more.

www.ebi.ac.uk/about/news/r...
🦠

30.09.2025 09:47 πŸ‘ 41 πŸ” 16 πŸ’¬ 1 πŸ“Œ 1
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Autocycler: long-read consensus assembly for bacterial genomes AbstractMotivation. Long-read sequencing enables complete bacterial genome assemblies, but individual assemblers are imperfect and often produce sequence-l

Happy to share that the paper describing Autocycler is now 100% up:
doi.org/10.1093/bioi...
(1/3)

29.09.2025 04:11 πŸ‘ 67 πŸ” 36 πŸ’¬ 1 πŸ“Œ 0

To summarise our recent pre-print: Autocycler, the automated consensus assembler, when used with Nanopore long-read only Enterobacterales assemblies, produces more complete chromosomes and plasmids, with an accuracy comparable to hybrid assemblies.

29.09.2025 06:57 πŸ‘ 26 πŸ” 16 πŸ’¬ 1 πŸ“Œ 0

A great opportunity to attend the #Shigella meeting April 20-24, 2026! Abstract submissions are open! @shigellameeting.bsky.social #Microsky

27.09.2025 12:03 πŸ‘ 8 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
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Come and join us at @shigellameeting.bsky.social in Paris 2026. Registrations are now open! www.shigella2026.conferences-pasteur.org/home and follow the Shigella starter pack go.bsky.app/6Vbwhjc (message to be added)! 215 days to go!

17.09.2025 11:57 πŸ‘ 18 πŸ” 9 πŸ’¬ 2 πŸ“Œ 1
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ggplot2 4.0.0 A new major version of ggplot2 has been released on CRAN. Find out what is new here.

I am beyond excited to announce that ggplot2 4.0.0 has just landed on CRAN.

It's not every day we have a new major #ggplot2 release but it is a fitting 18 year birthday present for the package.

Get an overview of the release in this blog post and be on the lookout for more in-depth posts #rstats

11.09.2025 11:20 πŸ‘ 850 πŸ” 281 πŸ’¬ 9 πŸ“Œ 51

Academia may not give you job security, flexibility, or wealth, but it will let you unexpectedly connect to eduroam in foreign cities

20.08.2025 16:58 πŸ‘ 1005 πŸ” 165 πŸ’¬ 30 πŸ“Œ 21

Really liked the explanation about human understanding, and what we miss when we use black box models. This has always been my gripe with prediction models for eg AMR - I want to know why that feature is associated with resistance!

12.08.2025 04:56 πŸ‘ 9 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Register today for the 14th International Meeting on Microbial Epidemiological Markers (IMMEM XIV)! Topics range from how genomics inform resistance profiling to pathogen surveillance in a #OneHealth framework. 🧬

✍️ Register: ow.ly/gjOZ50WpOXX
πŸ‘€ Programme: ow.ly/Whj850WpOXY

#IDSky

07.08.2025 08:14 πŸ‘ 5 πŸ” 6 πŸ’¬ 0 πŸ“Œ 1
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This surprisingly relaxing footage is from SIX MILES under the ocean – and it’s the deepest ecosystem yet discovered

31.07.2025 15:38 πŸ‘ 14184 πŸ” 3420 πŸ’¬ 431 πŸ“Œ 525

Huge amount of work in this paper, very proud of Hugh getting through all these benchmarking tests. We’re much more confident now using ONT-only data for our clinical questions

30.07.2025 08:34 πŸ‘ 6 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Graph showing IS loads by Klebsiella sub-lineage

Graph showing IS loads by Klebsiella sub-lineage

New preprint where we analysed IS loads in 🦠 #Klebsiella pneumoniae lineages and found they're inversely associated with nutrient usage. We propose an insertional tolerance model, whereby IS can only insert into metabolically-tolerable sites.

#IDSky #MicroSky πŸ§ͺ

www.biorxiv.org/content/10.1...

29.07.2025 02:29 πŸ‘ 18 πŸ” 8 πŸ’¬ 1 πŸ“Œ 0
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Fold first, ask later: structure-informed function annotation of Pseudomonas phage proteins Phages, the viruses of bacteria, harbor an incredibly diverse repertoire of proteins capable of manipulating their bacterial hosts, inspiring many medical and biotechnological applications. However, t...

Fold first, ask later: structure-informed function annotation of Pseudomonas phage proteins

Structural predictions to improve #phage genome annotation!

@hannelorelongin.bsky.social @gbouras13.bsky.social y.social @susiegriggo.bsky.social @veravannoort.bsky.social

www.biorxiv.org/content/10.1...

22.07.2025 00:27 πŸ‘ 46 πŸ” 25 πŸ’¬ 0 πŸ“Œ 0
Registration and abstract submission for MicroSeq2025 is open. Abstract submission closes August 8, 2025. Participants can register at microseqconference.com. MicroSeq2025 is an online meeting being held on September 3rd and 4th, focused on research being conducted on sequencing data generated from microbiological samples (bacteria, fungi, and viruses). MicroSeq2025 is supported by The Australian Society for Microbiology, the Australasian Virology Society, and Microbial Genomics.

Registration and abstract submission for MicroSeq2025 is open. Abstract submission closes August 8, 2025. Participants can register at microseqconference.com. MicroSeq2025 is an online meeting being held on September 3rd and 4th, focused on research being conducted on sequencing data generated from microbiological samples (bacteria, fungi, and viruses). MicroSeq2025 is supported by The Australian Society for Microbiology, the Australasian Virology Society, and Microbial Genomics.

🚨Abstract submission & registration for #MicroSeq2025 is OPEN! 🚨Get in quick! The first 50 registrations are FREE for PhD students and ECRs who are current ASM members, thanks to @aussocmic.bsky.social.

Head to our website to register now πŸ‘‡
www.microseqconference.com/registration...

21.07.2025 02:16 πŸ‘ 8 πŸ” 13 πŸ’¬ 1 πŸ“Œ 1