Guo Huang Lab @UCSF #Recruiting postdocs

It’s out! 🐟 We compared three regeneration superstars—axolotl, zebrafish, and Polypterus—to ask how animals regrow limbs and fins. We find shared core processes, and other programs fine-tuned by evolution in surprising, lineage-specific ways. tinyurl.com/mpftkn7y

Peripheral cancer attenuates amyloid pathology in Alzheimer’s disease via cystatin-c activation of TREM2 Peripheral cancer inhibits amyloid pathology and rescues cognition of Alzheimer’s disease through secretion of cystatin-c (Cyst-C), which binds amyloid oligomers and activates TREM2 in microglia and e...

A landmark discovery in cancer neuroscience! Why is the incidence of Alzheimer’s disease (AD) lower in patients with a history of cancer? CELL: Peripheral cancer attenuates amyloid pathology in Alzheimer’s disease via cystatin-c activation of TREM2 www.cell.com/cell/fulltex...

So proud of this incredible team and all we accomplished this year!

We’re looking for 1-2 postdocs to explore evo-devo, organ regeneration, extreme physiology, non-traditional animals, and

SUPERMAN 🦸‍♂️!

Please spread out news.
@isrbio.bsky.social @ahascience.bsky.social @socdevbio.bsky.social

Here is a copy of last year's Twitter thread explaining our preprint - jump to (21) for the new stuff 👀

Synergy between cis-regulatory elements can render cohesin dispensable for distal enhancer function

now revised and journal accepted at www.science.org/doi/10.1126/...

🧵👇

Nice to see it in print finally, Elphege. Congratulations on the beautiful work!

We've just been awarded a grant to study the cellular basis of regeneration – to track the progenitors of sensory organs in the context of leg regeneration, in our favourite crustacean tinyurl.com/parhyale, based on live imaging and cell tracking. The project involves some cool collaborations... 1/3

NIH announces end to funding for animal-only studies - Drug Discovery and Development Drug Discovery and Development covers strategies and technologies related to pharmaceutical research and development and drug formulation.

All new NIH funding opportunities should incorporate New Approach Methodologies, a suite of modern alternatives including computer modeling, AI and ‘organs-on-a-chip’ technologies. “NIH will no longer seek proposals exclusively for animal models.” www.drugdiscoverytrends.com/nih-announce...

Congrats, Arica! Great to see it in print!

Border-zone cardiomyocytes and macrophages regulate extracellular matrix remodeling to promote cardiomyocyte protrusion during cardiac regeneration Nature Communications - Adult zebrafish are capable of heart regeneration, but how the collagenous injury site is replaced remains unclear. Here they provide an in-depth analysis of cardiomyocyte...

Very excited to see the first Beisaw lab publication out in its final form 🥳🥳 rdcu.be/ei1I7 if you’re interested in zebrafish heart regeneration and how cardiomyocytes replace the fibrotic injured tissue (spoiler alert: macrophages play an important role), then read it here 👇

There is still time to apply! Come and join us!

Now our job post is out in Nature Careers. We have recruited one and have a few more positions. Please spread the news. nature.com/naturecareers/…

We're recruiting postdocs interested in regenerative biology and extreme physiology! Join us to study non-model mammalian species and rare human individuals to uncover groundbreaking insights. Please spread the news. @isrbio.bsky.social @evodevopanam.bsky.social

This was an internal announcement from the grant office of a university. There are similar notices from other universities. For example, osp.unc.edu/2025/02/nce-...

No more no-cost extension for NIH grants!

Happy to host my friend Dr. Doug Anderson as the speaker for our first seminar in 2025 @ucsanfrancisco.bsky.social #UCSF_CVRI. If you are interested in RNAs and his novel gene stitching approach (just published in @science.org: science.org/doi/10.1126/sc…), please join us. Sorry no Zoom option.

Happy Holidays from the Huang lab! #UCSF_CVRI @UCSF Good news: Marco de Leon receives @americanheart.bsky.social Postdoc Fellowship! Congrats! Now we have open positions. If you’re interested in joining us, please contact me. @isrbio.bsky.social @evodevopanam.bsky.social @americanheart.bsky.social