Spatial Technology Platform - Broad Institute of MIT & Harvard

I'm very excited to be presenting at #ESHG2025 in Milan about our work with Illumina Spatial Technology - Interactive Exploration of Single-Cell Transcriptome-Wide 3D Reconstruction using Celldega

www.linkedin.com/posts/ismahe...

@stp-broad.bsky.social

@broadinstitute.org

bit.ly/celldega

CellFIE: Integrating Pathway Discovery With Pooled Profiling of Perturbations Uncovers Pathways of Huntington’s Disease, Including Genetic Modifiers of Neuronal Development and Morphology Genomic screens and GWAS are powerful tools for identifying disease-modifying genes, but it is often challenging to understand the pathways by which these genes function. Here, we take an integrated a...

Congratulations to our graduate student, Brian Kang, on his recent preprint showing a method for finding risk pathways in Huntington’s disease using computational nomination and highly multiplexed immunofluorescence in collaboration with Dr. Ernest Fraenkel at MIT!
www.biorxiv.org/content/10.1...

We are very excited to share our collaboration on 3D reconstruction developing mouse cranium using Illumina spatial technology featuring bit.ly/celldega at #AGBT. View the Workshop on demand here:

www.illumina.com/events/webin...

@mich-lipi.bsky.social
@cornhundred.bsky.social

Thanks @martinalexsmith.bsky.social and we’re glad you liked the 3D visual of #illumina data from bit.ly/celldega. Amazing work @mich-lipi.bsky.social and @stp-broad.bsky.social team!!

My favourite talk so far, @mich-lipi.bsky.social from @broadinstitute.org presented stacked #Illumina spatial slides of the mouse brain transcriptome with subcellular resolution #AGBTGM
I'm sold on spatial now...

It’s so nice to see our technology in the hands of amazing scientists! Michal Lipinski you rocked the talk at AGBT!!

Illumina unveils first-of-its-kind spatial transcriptomics technology

STP collaborating with Illumina, Inc. soon offering unbiased whole-transcriptome, high resolution, high sensitivity 50mm x 15mm capture areas!

www.illumina.com/company/news...

Spatial -omics: "Location, location, location" applies to biology, too YouTube video by Broad Institute

What a cell does depends on its location. Experiments like single cell sequencing strip away signs of where a cell was in its original organ or tissue. New spatial -omics techniques collect in-depth molecular data from cells while retaining that spatial information. Learn more: youtu.be/izhZ9VB1jRM

Q&A: How a Broad team uses cutting-edge spatial technologies to enable new science Sami Farhi, director of Broad’s Spatial Technology Platform, describes how the group, launched in late 2022, supports scientists who want to study cells and tissues with spatial context.

The Broad’s Spatial Technology Platform supports scientists who want to study cells and tissues with spatial context. In a Q&A, STP director Sami Farhi explains how the team makes spatial tools more accessible and employs them for scientific discovery.