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Gosia Trynka

@gosiatrynka

Science Director of OpenTargets and Group Leader at Wellcome Sanger Institute Genetics, immunology, drug discovery Outdoors, cats, dogs and all animals Views are my own

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13.12.2024
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Latest posts by Gosia Trynka @gosiatrynka

Senior Postdoctoral Fellow Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity’s greatest challenge...

Hiring Senior Computational Postdoc to lead large-scale scRNAseq analysis for Project JAGUAR, one of the world’s most comprehensive single-cell immune resources from Latin American ancestries. If big data, global partnerships, human diversity and immune regulation excite you, apply! bit.ly/3XyFWrW

04.12.2025 09:06 👍 7 🔁 8 💬 0 📌 0
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Beyond Transcriptomics: Can Imaging Bridge the Gap in Variant Interpretation?-join @hkilpinen.bsky.social @melinaclaussnitzer.bsky.social Alessandro Palma from @fabiantheis.bsky.social @enoutahi.bsky.social and myself at #ASHG25 for our Featured Symposium.

11.10.2025 17:19 👍 9 🔁 1 💬 0 📌 1
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Leena Peltonen School of Human Genetics in full-swing!

@gosiatrynka.bsky.social
@dgmacarthur.bsky.social
@bpasaniuc.bsky.social
@tuuliel.bsky.social
@hilarycmartin.bsky.social
@sashagusevposts.bsky.social
@zkutalik.bsky.social
@mashaals.bsky.social
@alemedinarivera.bsky.social

30.07.2025 10:04 👍 56 🔁 9 💬 0 📌 6
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Today, the Scientific Programme Committee wrapped a fantastic and exciting programme for #eshg2026 conference! More information will available on our conference website soon. We look forward to welcoming you in Gothenburg!

27.06.2025 11:00 👍 14 🔁 5 💬 0 📌 2

It was a great pleasure hosting you in the group, Juliana! Wishing you all the best in your research!

27.05.2025 17:52 👍 2 🔁 0 💬 0 📌 0

A clever use of cat pictures in your thread, it kept me scrolling through to the end! Oh, and the use of @opentargets.org Platform wasn't too bad either ;)

16.04.2025 08:50 👍 4 🔁 0 💬 0 📌 1

Together with @pacbio.bsky.social, we’re building open datasets, new tools, and a better understanding of biology, one that’s truly global.

15.04.2025 15:21 👍 1 🔁 0 💬 0 📌 0

This is a technical and scientific milestone: long-read, single-cell transcriptomics at scale, across cell types and tissues, and across diverse populations.

15.04.2025 15:21 👍 1 🔁 0 💬 1 📌 0

Alongside, @carlanderson.bsky.social and his team will apply this technology to IBD. By resolving RNA isoforms in blood and gut tissue, they hope to uncover why treatments work better for some than others, and how to improve them.

15.04.2025 15:21 👍 1 🔁 0 💬 1 📌 0

This matters because underrepresented populations have been left out of large-scale genomic studies for too long.
By centering these communities in cutting-edge research, we’re helping pave the way for more equitable health outcomes.

15.04.2025 15:21 👍 1 🔁 0 💬 1 📌 0

Samples from Peru 🇵🇪 and Mexico 🇲🇽 will help reveal how transcriptional complexity varies across ancestries, bringing much-needed diversity to immune research and ensuring genomic insights reflect all of global population.

15.04.2025 15:21 👍 1 🔁 0 💬 1 📌 0

Project JAGUAR is at the heart of this.

We’re working with scientists across 7 Latin American countries to study how genetic ancestry shapes immune responses. We will use long-read single-cell RNA sequencing for the first time at scale.

15.04.2025 15:21 👍 2 🔁 0 💬 1 📌 0

📢🌎 A big step forward for inclusive genomics
Announcing a major collaboration between @sangerinstitute.bsky.social @pacbio.bsky.social to map the hidden language of genes in the immune system at single-cell resolution.

👇Why this matters, especially for underrepresented populations:

15.04.2025 15:17 👍 8 🔁 2 💬 1 📌 0

Postdoc opportunity to join @maryellenlynall.bsky.social and my group on this exciting project to look into the genetic drivers of immune system deregulation in schizophrenia.

22.02.2025 19:45 👍 3 🔁 0 💬 0 📌 0

Less than a month to apply! If you're a PhD student in human genetics, don't miss this unique opportunity. We have a stellar lineup of tutors promising immersive scientific and mentoring discussions.

17.02.2025 06:58 👍 1 🔁 1 💬 0 📌 0
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Randomizing the human genome by engineering recombination between repeat elements We lack tools to edit DNA sequences at scales necessary to study 99% of the human genome that is noncoding. To address this gap, we applied CRISPR prime editing to insert recombination handles into re...

We're delighted to share our work on scrambling the human genome using prime editing, repetitive elements, and recombinases in @science.org , led by @jonaskoeppel.bsky.social , @f-raphael.bsky.social , with @proftomellis.bsky.social and George Church.
www.science.org/doi/10.1126/...

31.01.2025 13:48 👍 139 🔁 61 💬 2 📌 5

Thank you, Adrian 😊

31.01.2025 16:36 👍 1 🔁 0 💬 0 📌 0
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Congratulations to Julie Matte from the @gosiatrynka.bsky.social lab on an exceptional thesis and defence!

31.01.2025 13:24 👍 12 🔁 1 💬 2 📌 0
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Huge congratulations to @jcmatte.bsky.social on passing her PhD viva 💫 It's been a privilege having you in the lab, watching you grow, pushing the boundaries and learning from you. I couldnt be more proud! Thank you to the examiners for your time & feedback! @labliston.bsky.social & CraigGlastonbury

31.01.2025 16:35 👍 5 🔁 0 💬 0 📌 0

looking to find folks who have current access to identified specimens (can be live or dead and well preserved) of many mosquito species. there are 3500ish described Culidae out there - anyone know anyone who might have specimens from 50+ species? please get in touch if so!

30.01.2025 18:00 👍 5 🔁 12 💬 1 📌 0
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From next spring, the Open Targets Platform will incorporate the best of Open Targets Genetics into an integrated drug discovery platform 🧵

17.12.2024 17:06 👍 18 🔁 7 💬 2 📌 0
LPSHG – Leena Peltonen Shool Of Human Genomics

🌟 Exciting news: The Leena Peltonen School of Human Genetics returns in 2025!

This prestigious summer school brings together leaders in human genetics with PhD students

📅 July 27-31, 2025

📍 Wellcome Genome Campus, UK

📝 Apply by March 7 at www.lpshg.com

19.12.2024 16:01 👍 4 🔁 4 💬 0 📌 2
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In the upcoming NAR issue, we summarise the last 2 years of updates in the @opentargets.org Platform. One step at a time... academic.oup.com/nar/advance-...

06.12.2024 17:06 👍 15 🔁 8 💬 1 📌 0