Hanieh Falahati

People I can’t recommend this enough! He is one of the most knowledgeable people I know, a great mentor AND a wonderful person

One for the Apicomplexa peeps:
ever wonder how does the IMC grow so fast during progeny formation? Where do all the lipids come from? In our latest work on malaria RBC stages we implicate this monster protein (~6000 residues!) and ER contact sites.
Happy+proud to share and keen to hear thoughts!

Nucleation-dependent propagation of Polycomb modifications emerges during the Drosophila maternal to zygotic transition During zygotic genome activation (ZGA) in Drosophila , broad domains of Polycomb-modified chromatin are rapidly established across the genome. Here, we investigate the spatial and temporal dynamics by...

www.biorxiv.org/content/10.1...

The Hanna lab opens this coming January in the Dept of Biochemistry and Molecular Biology at Penn State Uni! Follow us as we uncover the mechanisms that respond to lysosome damage

A very special first post on Bluesky: I’m excited to share that I’ll be starting my lab at Penn State this coming January in the Dept of Biochemistry & Molecular Biology! I’ll be hiring at all levels soon. Check out updates, thoughts, and positions on the lab account: @hanna-lab.bsky.social

Light-microscopy-based connectomic reconstruction of mammalian brain tissue - Nature A technique called LICONN (light-microscopy-based connectomics) allows mapping of brain tissue at synapse level and simultaneous measurement of molecular information, thus enabling quantification of c...

Mo and Hans's work here is truly a landmark in dense structural imaging, but the proof of the pudding is in the eating. Do yourself a favor and check out the Neuroglancer links and get an early glimpse at a technique I'm confident we'll see more and more over the next few years.

It was my pleasure :)

Meet our Speakers: Dr. Roberto Zoncu As a scientist, starting from my postdoc and continuing in my own lab, we have helped redefine the role of the lysosome. Historically, it was considered a

Earlier this month I had the honor of interviewing Dr. Zoncu @robzonculab.bsky.social during his visit to Yale. It was so inspiring- and also fun! Here is a link: medicine.yale.edu/cellbio/news...

The bridge-like lipid transport protein VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damage Nature Cell Biology - Wang et al. show the recruitment of the lipid channel protein VPS13C and formation of VPS13C-dependent contacts between endoplasmic reticulum and lysosomes after lysosomal...

"The bridge-like lipid transport protein VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damage" out now in Nature Cell Biology
rdcu.be/ehbaL

Congratulations! Such an inspiring work 😊

Inhibitory specificity from a connectomic census of mouse visual cortex - Nature Using volumetric electron microscopy, the authors map and analyze the structure of cortical inhibition with synaptic resolution across a column of visual cortex.

It's been done for a while, accepted almost a year ago, but I'm happy to share that my first analysis of the MICrONs cubic mm dataset is online! nature.com/articles/s41...

When the 1st Muslim ban was about to go into effect, I was toward the end of my PhD. I went to Eric’s office in tears to ask if I could still defend my thesis and get a PhD if my legal status was revoked. I was lucky but I am heartbroken that this is actually happening to some students now

Random small reason to be happy: I have got 777 citations today 😄 my favorite number is 7

Princeton considers issuing bonds same day as federal government pauses grants The University announced its consideration to sell approximately $320 million of taxable bonds on Tuesday, following a notification from government agencies about the suspension of research grants.

Princeton has announced that it is considering selling approximately $320 million of taxable bonds. The bonds are a way for the University to raise short-term funds. The major credit-rating agencies rate University bonds AAA, the highest level of creditworthiness.

Like the cultural revolution, when anyone smarter than the regime was fired and sent to the countryside. Mao-Tse Trump.

My condolences …

Worth following @fly-broadcast.bsky.social for new fly papers on PubMed. They deserve a lot more than 50 followers!
@bdsc.bsky.social @flybase.bsky.social @fly-eds.bsky.social @dgrc.bsky.social

Induced proximity at the cell surface - Nature Biotechnology Technologies to modulate induced proximity at the cell surface advance the manipulation of diverse biological responses.

Check out our new review on induced proximity modalities (#TPD and a lot more!) aimed cell surface targets @naturebiotech.bsky.social, spearheaded by postdocs Nick Till and "Rahm" Ramanathan

www.nature.com/articles/s41...

regarding Columbia University, I just learned about this (anonymous) account of negotiations of the Hitler regime in the 1930s with Frankfurt University -- Germany's most prestigious university at the time:

Oh thank you ☺️

In this belated, crazy, #EM_Monday I am posting an image I took showing some organellar communications at a neuronal soma: a mitochondria contacting nuclear envelope, and Golgi going all the way from nuclear envelope to plasma membrane.

Honored to be featured this week by @yaleneuro.bsky.social in honor of my Life Sciences Research Foundation @hhmi.org fellowship!

Title, authors and abstract from link

In a remarkable new paper, Qureshi and Duss use multi-colour single-molecule fluorescence microscopy to directly and simultaneously track transcription, translation & coupling 3/n
www.nature.com/articles/s41...

Thrilled & honored to be a recipient of a Sloan Fellowship in Chemistry. Thanks for my mentors, colleagues and most importantly my students, for making this possible. #SloanFellow.

Four Yale faculty members win Sloan Research Fellowships Yale’s Amir Haji-Akbari, Tristan Geiller, Ian Moult, and Shreya Saxena have received 2025 Sloan Research Fellowships, which recognize outstanding early-career scientists and scholars.

So proud of @hajiakbari.bsky.social!!
news.yale.edu/2025/02/19/f...

And then comes the firing of scientists…

I feel sick to my stomach… what is happening to US science

This is great!

Everything you always wanted to know about the Axon Initial Segment might be here: authors.elsevier.com/sd/article/S...

Thanks Lorena ☺️