Leah Shaffer

Keeping it real

an old timey stock ticker machine under a glass dome, like in Trading Places! Most stock market literacy comes from Trading Places.

I assumed you were directly feeding bluesky dot com your ticket tape.

We're all at the mercy of our peers and social bubbles for shaping our worldviews. Dorsey hangs out with the "wrong crowd" in that he is mostly living life in the silicon valley pickle jar, a sheltered place where sensitive brains are not exposed to the full brunt of fact-based reality.

Thanks for sharing experiences, our fickle immune system is probably not to be trusted. Time for boosts.

He was chased off in early days because this unique tech community can be very very aggravating to those types (complimentary).

ughhh, I hate setting up appointments, was hoping it would be good enough protection, but I probably better get titers checked.

There was a "dead" version of the vaccine that wasn't as effective, administered between 1963 and 1967. So folks who got the shot during those years should get titers checked?

"If you got the standard two doses of the measles, mumps, and rubella (MMR) vaccine after 1967, you should be protected against the measles for life."
So, I think my elder millennial ass is protected.

The most appealing aspects of Bluesky's origins

A. Enabling Blacksky build

B. chased off Dorsey

C. The brief but glorious period when site was mostly just shitposters shitposting for the love of the game

Index provides flu risk for each state Researchers at WashU have developed vulnerability maps highlighting regions across the United States with varying levels of socioeconomic vulnerability to influenza-like illness.

Flu risk index, a unique risk assessment for each state based on socioeconomic and health factors that drive infection rates. #PublicHealth #InfectiousDisease
#MedSky 🧪 🩺
We would hand this to the CDC but wherefore art thou?
@cidrap.bsky.social Interested?
source.washu.edu/2026/03/inde...

This is sucky, people feel powerless and can't directly attack the source of evil but must attack someone to feel better. It's a shitty shitty social media dynamic that no social media structure has been able to effectively address.

RFK Jr. gets yelled at.
"You have chosen your own ego and profit over the health of children. You want children to suffer from disease and pain? That is the path you have chosen."
Imagine that clip goes viral. The outrage, the shame, algorithms love that shit. Would that do more good, or bad?

I have very mixed feelings on this. Yes, best practice is open listening and respectful engagement with concerns. But when that fails, what is the role of public shaming? "Shame" can establish new norms, reshape the conversation, but it's hard to know how and when to engineer a "shame" campaign.

@piperformissouri.bsky.social look at Mark, using such fancy flowery language. I think we should have a "conscious uncoupling" of this "kinetic conflict"

"We messed up. We were not listening. We are now. ICE officials will no longer have access to Target property. We are hiring a Black COO to immediately begin reaching out to community leaders and begin the work to regain trust."

That single statement might save you billions, Target.

Cooper's hawk or Sharpshin, always hard to tell difference. Usually around the metro, Cooper's hawks are most common. Got a couple of "newlyweds" in my neighborhood.

Feats of Strength!!! Look at her. Strong. bsky.app/profile/john...

Feats of Strength for the Skyline

Richest dude in town has to come out of his mansion in his slippers and bathrobe to scream at the criminal gangs who have chosen his lighter fluid factory as staging ground to toss molotovs around. Let's hope this gambit works.

time for a break

Gonna need some real change in the Orc Guard, it's been just way too chaotic with slaughter. MarkWaynegrimaWormtongue, can bring some professionalism back to the murder squads.

But other Democrats, including Sen. Chris Coons of Delaware, left the door open to supporting the eventual nomination.

“I’m open to it, but he’s going to have to make real changes,” Coons said, about the foul, sweaty goblin from OK.

Both Tillis and Murkowski praised Grima Wormtongue Thursday in the immediate wake of Trump’s announcement.

“He’s a man of his word. I think he’ll go in, get experts in there, and prove to be an executive with the right kind of skills, and get things squared away quickly,” Tillis said.

Fetterman is the the one Dem, I feel insane that this entire article reads as if this is all super normal: normal guy, normal party yup, yup, smooth sailing. It notes at the end that Schumer is still planning to block DHS funding.

The rise of Ozempic: how surprise discoveries and lizard venom led to a new class of weight-loss drugs Ozempic generated A$21 billion of sales in 2023 alone. So how was it developed? And how are its new competitors, Mounjaro and Zepbound, different?

GIP and GLP and glucagon, the trifecta of receptors to target.
German physician and scientist Matthias Tschöp and American chemist Richard DiMarchi, are continuing to refine this approach. 🧪 🩺 🔬 ⚗️ These drugs are a big bag of mysteries but not magic beans!
theconversation.com/the-rise-of-...

Biochemist John Pisano, started messing with lizard hormone brew back in 84. www.jbc.org/article/S002... pubmed.ncbi.nlm.nih.gov/1478791/

Structural requirements for biological activity of glucagon-like peptide-I - PubMed Glucagon-like peptide-I (GLP-I) is encoded together with glucagon by the glucagon gene and is related in its structure to the glucagon-secretin family of peptides. Three of the predicted forms of the peptide, a 37-residue long GLP-I(1-37), a 31-residue GLP-I(7-37) and a 30-residue GLP-I(7-36)amide a …

Her original paper outlining the scaffolding of our blockbuster drug pubmed.ncbi.nlm.nih.gov/1478791/

Her work paved the way for blockbuster obesity drugs. Now, she’s fighting for recognition Svetlana Mojsov helped discover the hormone GLP-1. Why has she been excluded from its history?

Even more shoutouts to be made: Science is a collective endeavor of a bunch of curious people pulling weird threads and muddling around in the dark.
Svetlana Mojsov, chemist extraordinaire for replicating this weird lizard hormone. #ChemSky 🧪
www.science.org/content/arti...

🤷‍♀️ we have much more to learn about these drugs

How a Canadian scientist and a venomous lizard helped pave the way for Ozempic - National | Globalnews.ca In 1984, Dr. Daniel Drucker, an endocrinologist from the University of Toronto, discovered a hormone that helped pave the way for popular diabetes drugs such as Ozempic.

Drucker needed an actual Gila monster to use in research and connected to reptile wrangler Bob Murphy who found one at a Utah Zoo.
"The Gila monster was flown into Toronto Pearson Airport and Murphy picked up the lizard." That was a very important gila monster delivery.
globalnews.ca/news/9793403...