Sarah Lebeer

Vitamin B2 Production by Vaginal Lactobacilli Promotes Symbiosis The human vaginal microbiome, particularly with lactobacilli as the main inhabitants, plays a key role in maintaining women’s health. While lactic acid-mediated pathogen exclusion is well known, broad...

Proud to announce a new preprint of our lb - deep dive into #immune #metabolomic mode of action of the #vaginalmicrobiome - thanks to Isala! Great collab with @zimmermannlab.bsky.social & almost entire PhD of @carolinedricot.bsky.social combined in one manuscript www.biorxiv.org/content/10.1...

Vitamin B2 Production by Vaginal Lactobacilli Promotes Symbiosis The human vaginal microbiome, particularly with lactobacilli as the main inhabitants, plays a key role in maintaining women's health. While lactic acid-mediated pathogen exclusion is well known, broad...

We are very happy to share a new preprint 🎉

Congratulations to everyone involved!
@carolinedricot.bsky.social, @denisemselegato.bsky.social, @sarahlebeer.bsky.social and co.

www.biorxiv.org/content/10.1...

The Global Grants for Gut Health are now open. If your research explores how nutrition affects the gut #microbiome or barrier function, you may be eligible to apply for one of three grants each offering up to USD$100K. Apply here: go.nature.com/4kb9cO1 #Academicsky 🍎📃

Vaginaal microbioom in kaart - Beste-ID

www.beste-id.nl/nieuws/vagin...
@uantwerpen.be @sarahlebeer.bsky.social

📢 2nd Keynote Speaker: Prof. Dr. Sarah Lebeer!!

@sarahlebeer.bsky.social is a research professor at the @Laboratory of Applied Microbiology and Biotechnology of the University of Antwerp working on the ecology and role of lactobacilli in women's health.

Indeed, they have a fantastic Instagram and design! ❤️

Uit onderzoek blijkt dat het ISS-ruimtestation té proper is. Prof. en moleculair bioloog @sarahlebeer.bsky.social #UAntwerpen legt uit hoe dat kan en waarom het een probleem vormt. @radio1vrt.bsky.social

www.vrt.be/vrtmax/luist...

Great meeting in Hongkong on the #microbiome!

Diversity in women and their vaginal microbiota Women’s health is essential to global societal and economic wellbeing, yet health disparities remain prevalent. The vaginal microbiota plays a critical role in health, with research indicating that re...

📢Sarah Lebeer (@sarahlebeer.bsky.social) and colleagues at the Isala team call for a more comprehensive, global, and inclusive understanding of the #vaginal #microbiome, critically reflecting on the use of 'race' and 'ethnicity' in studies.

Read the Opinion piece here: www.cell.com/trends/micro...

Agricultural practices and pollinators modulate the anthosphere microbiome Abstract. The flower microbiome is pivotal in plant health, influencing reproductive success, fruit quality, and pathogen vulnerability. However, the impac

Agricultural practices and pollinators modulate the anthosphere microbiome

#ISMEComms from @sarahlebeer.bsky.social

academic.oup.com/ismecommun/a...

First page of the Opinion article "Diversity in women and their vaginal microbiota" published in Trends in MIcrobiology

Global “sisterhood” of citizen scientists collaborate to understand what makes a healthy vaginal microbiome. www.cell.com/trends/micro...

@cp-trendsmicrobiol.bsky.social
University of Antwerp @sarahlebeer.bsky.social

Super proud of our Isala sisterhood!

“Dit is het antwoord op de resistentiecrisis”: Antwerpse bio-ingenieurs ontvangen Europese beurs voor onderzoek naar 'levende antibiotica’ Bio-ingenieurs van de Universiteit Antwerpen hebben een prestigieuze ERC Proof of Concept-beurs ontvangen voor hun baanbrekende VALERIE-project. Dit onderzoek richt zich op de ontwikkeling van ‘levend...

Our ERC POC grant covered in the national newspaper: www.hln.be/antwerpen/di...

💡 Orthogroup fixation frequency = proportion of species where the orthogroup is part of the species-level core genome relative to the number of species where the orthogroup is part of the species-level pangenome  --> new concept thanks to tool

Stijn Wittouck applied the core, sample and pan modules to infer a representative pangenome for over 31,000 (!) genomes of the order #Lactobacillales – without use of super computer!

Applicable for all taxa, but of course we used it for our favorite bacteria #lactobacilli: when ran on a dataset of 720 genomes of the genus #Lactiplantibacillus, this resulted in the identification of 2,093 core genes in 11 (!) minutes

🏆 When benchmarked against existing tools, the SCARAP pan module proved up to an order of magnitude faster with comparable accuracy

SCARAP contains three modules for #comparative #genomics analyses of bacteria 🧬
(1)     a fast and scalable pangenome inference module
(2)     a direct core genome inference module 
(3)     a module for subsampling representative genomes in linear time

Here is the link to the GitHub: github.com/swittouck/sc...

SCARAP: scalable cross-species comparative genomics of prokaryotes AbstractMotivation. Much of prokaryotic comparative genomics currently relies on two critical computational tasks: pangenome inference and core genome infe

New tool of the lab is out for scalable led by Stijn Wittouck #comparative #genomics in #bacteria across species and large datasets without super computer 💪💪 : academic.oup.com/bioinformati....

Citizen science as an instrument for women’s health research - Nature Medicine Citizen-science approaches can help challenge taboos around intimate health topics, amplify underrepresented voices and prioritize women’s involvement in health research; this Perspective considers th...

Proud to present our most recent paper on #citizenscience #womenshealth #microbiome on this new platform - from our Isala project www.nature.com/articles/s41...