The most sensitive green and red #norepinephrine #sensors engineered to date are out in #naturemethods! Deeply grateful to all our funders and contributors who made this work possible. A true team effort. @erc.europa.eu @snsf.ch doi.org/10.1038/s415...
Microscopy image of keratin (cyan) and desmosomes (magenta)
There are an extremely limited number of open slots for the Analytical and Quantitative Light Microscopy @aqlm.bsky.social course at @mblscience.bsky.social April 29-May 8 2026.
www.mbl.edu/education/ad...
Apply here for this amazing opportunity!
Figure showing the comparison between spinning disk (SD) confocal, SIM and ExM when imaging Drosophila cemtrioles.
Emma Burns, Anastasia Amoiroglou, Gregory Rogers, Nasser Rusan and colleagues develop an expansion microscopy protocol for Drosophila cultured cells and tissues, which they use to dissect centriole biology.
journals.biologists.com/jcs/article/...
Prime numbers 2-4999, animated with ggplot2+gganimate.
#Rstats code: gist.github.com/stephenturne...
Don't miss out. Apply to our 2026 Advanced Research Training Courses today!
🚨 Job Alert! 🚨
We have an opening at our Microscopy Core Facility in Turku 🇫🇮.
If you love imaging 🔬 and helping scientists succeed, we want you! 👇
abo.rekrytointi.com/paikat/index...
#Microscopy #ScienceJobs #CoreFacility #Imaging
@turkubioscience.bsky.social
DC, Winter 2025
My lab in the NIH Intramural Program (Bethesda, MD) will be recruiting postdoctoral fellows over the next year with flexible start dates. We work on nanoscale cellular imaging of the plasma membrane and related organelles. Please reach out if you’re interested. www.training.nih.gov/jobs/pdp-053...
We have a number of fluorescent protein pairs here that are great for FLIM www.addgene.org/browse/artic...
Yes! Many of our plasmids are here www.addgene.org/Justin_Taras... and both NPY-GFP (exocytic vesicles) and clathrin light chain-GFP (endocytic sites) make excellent sub-diffraction biological targets.
We're thrilled to announce the largest private gift in our 137-year history: a $25 million unrestricted donation from MBL Whitman Scientist Mark Terasaki.
His extraordinary generosity will bolster our renowned research and education programs. 🔬
Learn more: bit.ly/452WL1m
Hoya bloom
Woods Hole, MA
Salt Lake from the air
Metro
Japanese Garden, Powell’s Bookstore downtown, Forest Park, SE Division or SE Hawthorne St, Coava coffee, OHSU gondola.
I am excited to share our first Pt replica EM images. It took us a little while, but now we have establish the unroofing, drying and Pt coating workflow 🎉 Great work by our postdoc Luis Wong Dilworth! The image below shows the cytosolic membrane leaflet of a fibroblast 👇
Super cool. Septin/actin rings maybe.
This is a scientific figure from the paper mentioned in the post. It shows fluorescence and electron microscopy images and associated schematics for using the ferritag to image clathrin coated pit proteins.
I'd like to draw your attention to this truly excellent paper from the Taraska lab on cryoET of plasma membrane associated proteins. Everyone who is thinking about probes in the cryoET space should also see what they could do with ferritag (fig 6) www.nature.com/articles/s41...
The deadline to apply for the MBL Physiology course is fast approaching, January 27th! Consider applying to this amazing, life-changing research discovery experience in Woods Hole! www.mbl.edu/education/ad...
Not necessarily unhappy. Muscle cells have extensive flat clathrin lattices. Some cells stimulated with EGF also have them. Highly metastatic cells can accumulate them. They are used as adhesion and receptor organization sites.
Is the third image at the bottom surface of the cell? Those are likely large flat clathrin lattices that can accumulate in some cell types at the bottom of the cell.
CD44 and Ezrin restrict EGF receptor mobility to generate a novel spatial arrangement of cytoskeletal signaling modules driving bleb-based migration https://www.biorxiv.org/content/10.1101/2024.12.31.630838v1
It’s incredibly exciting when a completely different approach supports an unexpected finding from your group. Recently, we published that LDLR is captured with EGFR and FGFR1 at clathrin sites after EGF stimulation. I love science.
www.molbiolcell.org/doi/full/10....
bsky.app/profile/scie...
