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Guillaume Charriere

@gm-charriere

Professor at Montpellier University, IHPE Lab, France. http://ihpe.univ-perp.fr/ihpe-charriere-guillaume/ Curious and interested in many aspects of phagocyte biology, vibrios, amoebae, oysters, host-pathogen co-evolution, and comparative immunology.

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Latest posts by Guillaume Charriere @gm-charriere

A chart depicting the track of claims into verified, unchallenged, challenged, partially verified, or mixed.

Figure 1: Flow of the study.
Claims were first classified in five categories based on literature. 45 unchallenged claims were selected to be experimentally tested and
classified either as challenged or as verified. We further classify some unchallenged as consistent or inconsistent depending on their
consistency with current knowledge.

A chart depicting the track of claims into verified, unchallenged, challenged, partially verified, or mixed. Figure 1: Flow of the study. Claims were first classified in five categories based on literature. 45 unchallenged claims were selected to be experimentally tested and classified either as challenged or as verified. We further classify some unchallenged as consistent or inconsistent depending on their consistency with current knowledge.

But in fact, fly immunity is highly reproducible! 🎊

~80% of claims could be verified. Moreover, some challenged claims just reflect the field advancing its knowledge/tools.

The lesson: if the tools are good and the research largely exempt from direct translation pressures, science works.

3.5/n

10.07.2025 08:21 👍 50 🔁 18 💬 2 📌 3
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Technicien en expérimentation animale (H/F)

L’IHPE recrute un-e technicien-ne en expérimentation animale. Date limite 11/7 recrutement.upvd.fr/poste/afifwk...

28.06.2025 05:43 👍 1 🔁 1 💬 0 📌 0
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Journals Operating Predatory Practices Are Systematically Eroding the Science Ethos: A Gate and Code Strategy to Minimise Their Operating Space and Restore Research Best Practice Scientific research seeks to extend knowledge and understanding, an activity that perhaps more than any other advances society and humanity. In essence, it is the search for truth. But, because it se....

Important: Journals Operating Predatory Practices Are Systematically Eroding the Science Ethos: A Gate and Code Strategy to Minimise Their Operating Space and Restore Research Best Practice enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...

21.06.2025 04:51 👍 3 🔁 1 💬 0 📌 0
Image Credit: Bob Goldstein, a black and white sketch of various organisms - butterfly, fish, worm, some sort of plant, a rodent, some un-named sea creatures.

Image Credit: Bob Goldstein, a black and white sketch of various organisms - butterfly, fish, worm, some sort of plant, a rodent, some un-named sea creatures.

🚨Call for papers on Non-traditional model organisms for #BMCBiology🚨

Guest Editors:
Eve Gazave @stemdevevo.bsky.social, @ijmonod.bsky.social
Vladimír Hampl, @sciencecharles.bsky.social
Jason Podrabsky, Portland State U
Deanne Whitworth, U of Queensland

www.biomedcentral.com/collections/...

16.06.2025 13:31 👍 15 🔁 7 💬 0 📌 0
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Exciting fundamental discovery!

Early embryos fight bacteria WITHOUT immune cells

Zebrafish, mouse, and human embryos use epithelial cells (trophoectoderm)—not immune cells—to engulf and destroy 𝘌. 𝘤𝘰𝘭𝘪 and 𝘚. 𝘢𝘶𝘳𝘦𝘶𝘴

Hoijman Lab Barcelona 🇪🇸
𝘊𝘦𝘭𝘭 𝘏𝘰𝘴𝘵 𝘔𝘪𝘤𝘳𝘰𝘣𝘦

www.sciencedirect.com/science/arti...

21.06.2025 05:06 👍 295 🔁 78 💬 7 📌 2

Congrats Angélique !!!

19.06.2025 15:55 👍 2 🔁 0 💬 0 📌 0
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Paramoeba atlantica as a Natural Intracellular Niche for Vibrios in Marine Ecosystems Various vibrios can colonise a large vacuole called VCV (Vibrio-containing-vacuole) within Paramoeba atlantica. The VCVs acidify and the vibrios multiply and remain alive inside the VCVs for hours. T...

Our last paper just came out ! A great piece of work from the talented Laura Onillon and teammates with the pleasure to share this adventure with friendly collaborators @vincentdlft.bsky.social and @soldatilab.bsky.social !

19.06.2025 15:53 👍 8 🔁 3 💬 0 📌 1

Thank you @soldatilab.bsky.social it was great to benefit from your inputs and expertise !

19.06.2025 15:46 👍 2 🔁 0 💬 1 📌 0
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PhD Summer School on Host-Microbe Symbioses 2025 Symbnet PhD Summer School on Host-Microbe Symbioses Gulbenkian Institute for Molecular Medicine (GIMM) & Católica Biomedical Research Centre (CBR) July 06...

Symbnet PhD Summer School on Host-Microbe Symbioses - Oeiras Portugal. Students from all over the world are eligible, we sponsor selected students. Please Repost!
gimm.idloom.events/phd-summer-s...

16.03.2025 12:26 👍 55 🔁 67 💬 1 📌 3

Check out our most recent preprint where we describe Mecp2 as a régulatrice of cGAS-STING associated signaling. 🧪🔥

05.02.2025 19:48 👍 15 🔁 10 💬 1 📌 2
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Problematic Paper Screener: Trawling for fraud in the scientific literature Science sleuths are stepping up efforts to detect bogus science papers. This includes building tools that comb through millions of journal articles for signs of tortured phrases spawned by AI.

Problematic Paper Screener: Trawling for fraud in the scientific literature

Have you ever heard of the Joined Together States?

our paper screener has been instrumental in more than 1,000 retractions

theconversation.com/problematic-...

31.01.2025 07:01 👍 70 🔁 12 💬 1 📌 0
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Between 2019 and 2023, researchers paid $8.968 billion to make papers open access. Imagine what else could be done with this money if it wasnt paid to for profit publishing companies...
👉 arxiv.org/abs/2407.16551

27.01.2025 00:33 👍 639 🔁 320 💬 18 📌 35
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‘Stamp out paper mills’ — science sleuths on how to fight fake research A group of scientists who are experts at spotting fraudulent research outline five essential steps to combat industrialized scientific misconduct.

I'm delighted to share our opinion on #papermills published in Nature. Science is flooded with papers from paper mills.Certain steps can be taken, but this is a challenge that neither universities nor journals are ready to face.Some use paper mills to their advantage.
www.nature.com/articles/d41...

27.01.2025 12:06 👍 139 🔁 80 💬 5 📌 15
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Newsletter CNRS:
'Création du label CNRS Keylabs. Pour faire face à la compétition internationale, le CNRS doit construire des masses critiques et faire porter un effort particulier sur un nombre plus restreint d’unités, celles qui peuvent légitimement prétendre à être qualifiée “de rang mondial”'

11.01.2025 14:45 👍 20 🔁 4 💬 0 📌 0
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Regulation of human interferon signaling by transposon exonization Transposable element exonization can yield functional protein isoforms as seen for primate-specific IFNAR2.
13.12.2024 13:57 👍 7 🔁 1 💬 0 📌 0
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Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55

11.12.2024 16:29 👍 693 🔁 294 💬 24 📌 65
Figure 8.2 from technical report on mirror bacteria, showing potential for net population growth and invasion of marine environment by mirror phototrophic bacteria.

Figure 8.2 from technical report on mirror bacteria, showing potential for net population growth and invasion of marine environment by mirror phototrophic bacteria.

Frequent Q is how mirror bacterium could persist in nature. Marine Prochlorococcus good example. Little downside in terms of competitiveness + resistant to protists and phages. Net positive growth allows invasion.

See Chapter 8 of technical report here:
purl.stanford.edu/cv716pj4036

13.12.2024 11:32 👍 26 🔁 7 💬 2 📌 0
Photo of the front page of the paper - showing animals and plants and people encircled across the globe - There needs to be more emphasis on the ecological component of One Health as we consider the problems of biodiversity loss, climate extremes, habitat fragmentation, and emerging disease. Image credit: Shutterstock/BeataGFX.

Photo of the front page of the paper - showing animals and plants and people encircled across the globe - There needs to be more emphasis on the ecological component of One Health as we consider the problems of biodiversity loss, climate extremes, habitat fragmentation, and emerging disease. Image credit: Shutterstock/BeataGFX.

Important piece by Gittleman - “It’s impossible to separate human health from health of the natural world. Ecology is the unifying science that integrates knowledge..[the] One Health approach is unlimited, exciting, & necessary for the health of life on our planet” www.pnas.org/doi/10.1073/... 🧪🌎🌐🌾

13.12.2024 10:48 👍 165 🔁 64 💬 3 📌 4
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I don’t normally stray here into politics, but this is global health and child mortality: somewhat terrified this will negatively impact not just public health in the USA, but could normalise this view further afield

13.12.2024 06:55 👍 93 🔁 28 💬 9 📌 4

Registration is now open for the 2025 Symposium on the Immune System of Bacteria, taking place this year in Paris (April 8-10).

We have a fantastic lineup of speakers!

Register here: www.sisb2025.conferences-pasteur.org/home

10.12.2024 06:24 👍 21 🔁 16 💬 1 📌 0

Plasmid afficionados: Does anybody know of any chromosomal genes that are required for plasmid conjugation? We have found a few by chance in a recent experiment and I would be really interested to know if there are other examples.
#microsky
#plasmid

27.11.2024 11:23 👍 64 🔁 32 💬 11 📌 0
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Bluesky is emerging as the new platform for science - Mike Young Academy Scientific Twitter is about to find its true successor. And it is not X. This, our latest release, shows that the Bluesky network of scientists is growing — and growing.

"Bluesky is emerging as the new platform for science"

mikeyoungacademy.dk/bluesky-is-e...

29.11.2024 10:13 👍 243 🔁 79 💬 1 📌 6
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The #Drosophila Immunity Handbook 🧵

This project started as a review with the aim, in some sense, to update Lemaitre and Hoffmann (2007; Ann Rev Imm). Then it kinda... got out of hand. But the reason that happened is because Hannah is amazing.

Find the free PDF here btw: bit.ly/DrosImmBook
1/n

14.09.2024 20:49 👍 31 🔁 27 💬 2 📌 3
The Alker lab at the University of Rhode Island is hiring (students, postdocs and lab staff)! We use cutting edge tools in microbiology to investigate marine animal symbioses. Email or DM for further inquiries

The Alker lab at the University of Rhode Island is hiring (students, postdocs and lab staff)! We use cutting edge tools in microbiology to investigate marine animal symbioses. Email or DM for further inquiries

🚨 The Alker Lab is starting at the University of Rhode Island in early 2025 and we will be hiring! 🚨

If you are interested in marine microbiology, bacterial genetics and/or symbiosis, please consider reaching out! Repost to help spread the word 🪸🧪🧬🌊

30.11.2024 00:13 👍 94 🔁 51 💬 7 📌 2
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"Un coup dur pour l’ascenseur social" : 17 millions en moins en 2025, l'Université de Montpellier inquiète du désengagement de l'Etat Face à un désengagement financier de l’État estimé à 17 millions d’euros en 2025, l’Université de Montpellier tire la sonnette d’alarme. Son président, Philippe Augé, dénonce un danger pour l’attracti...

Universités en Danger 🚨 L’UM alerte sur un désengagement financier de l’État (-17 M€ en 2025). Son président, Philippe Augé, pointe un risque majeur pour l’attractivité de l’enseignement supérieur et le rôle social des universités. ⤵️

france3-regions.francetvinfo.fr/occitanie/he...

29.11.2024 17:08 👍 7 🔁 10 💬 0 📌 0
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A Toulouse, une école universitaire de recherche formera les prochains experts des maladies infectieuses émergentes à partir de la rentrée 2025 - Université Toulouse III - Paul Sabatier

A Toulouse, une école universitaire de recherche formera les prochains experts des maladies infectieuses émergentes à partir de la rentrée 2025 👇
www.univ-tlse3.fr/actualite-de...

29.11.2024 15:58 👍 6 🔁 3 💬 0 📌 0
chalk + chalkboard with diagrams

chalk + chalkboard with diagrams

lab group silly picture

lab group silly picture

Wow - bluesky! 📈 🦠

Please help me amplify a special faculty search. We're looking for someone in "Microbial Systems Biology" to join me and @kreynoldslab.bsky.social at UTSW Sys Bio / Bioinformatics.

There is an empty lab space right next to us waiting for you!

apply.interfolio.com/154339

1/4

22.11.2024 17:49 👍 94 🔁 103 💬 3 📌 0
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Reading this fabulous, honest and revealing autobiographical article by John Hopfield « Now what? » on finding a good research problem.
I think this is a must read. I note the importance of teaching and serendipity.

pni.princeton.edu/people/john-...

23.11.2024 08:07 👍 43 🔁 14 💬 0 📌 2