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Thomas Höfler

@hoeflet

Infection biologist, virologist, molecular biologist. Postdoc @K-State 🦠🦠 All about #viruses and how they can do better #herpes #evolution

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11.12.2024
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Latest posts by Thomas Höfler @hoeflet

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Rapid glycoprotein evolution enables variant interactions in herpes simplex virus type 1 Abstract. Glycoproteins cover the surface of enveloped viruses such as herpes simplex virus 1 (HSV-1). Whilst essential for cellular attachment and entry,

New paper alert 🚨
Check out our latest article about #social interactions in #herpesvirus populations via #glycoprotein variants, now in @Virus_Evolution. Thanks to everyone involved, also to the very supportive reviewers who definitely improved the manuscript!
academic.oup.com/ve/article/1...

09.10.2025 15:46 👍 1 🔁 1 💬 0 📌 0

Open postdoc position in in my lab in Berlin @mpiib-berlin.mpg.de.

Join us to push the frontier in ancient microbial genomics. Please apply until Oct 17th. Reach out in case you have any questions.

www.mpiib-berlin.mpg.de/2193291/job_...

15.09.2025 08:03 👍 22 🔁 28 💬 1 📌 0
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Gonna present some exciting work on mutation rates, population bottlenecks and defective genomes. Come and see me later today for my flash talk and poster presentation at #IHW25 in #Berlin.

29.07.2025 10:41 👍 1 🔁 0 💬 0 📌 0

I‘ll present my poster on „Rapid glycoprotein evolution enables variant interactions in Herpes Simplex Virus type 1“ on Thursday 17th of July at #ASV2025 in #Montreal. If you are looking for me though, due to severe weather I‘ll only arrive tomorrow 😬. See you guys tomorrow!

14.07.2025 20:01 👍 4 🔁 0 💬 0 📌 0
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Complex interactions in the life cycle of a simple parasite shape the evolution of virulence Author summary Classical expectations on parasite evolution assume a trade-off between transmission rate and harm to the host (virulence), favoring parasites with intermediate virulence. However, rece...

OUT in @PLOS #Pathogens! 🦠🦟
We evolved a parasite to transmit early/late from its #Anopheles host—spending less/more time inside. We ask what this means for #transmission, social #behaviour, classical #virulence theory, and (mis)used composite virulence metrics.
#MicroSky
1/3
doi.org/10.1371/jour...

30.06.2025 18:39 👍 9 🔁 7 💬 1 📌 0

I made a starter pack for researchers who study various aspects of viral sociality. It's woefully incomplete and has lots of room to grow, so do message me if I've missed you!

go.bsky.app/3PfgjkP

#SocialViruses 🦠 🧪

17.11.2024 14:40 👍 23 🔁 14 💬 2 📌 1
This is figure 1, which shows pasteurisation effectively inactivates influenza viruses in milk.

This is figure 1, which shows pasteurisation effectively inactivates influenza viruses in milk.

In response to the emergence of H5N1 influenza A viruses as a novel pathogen of cattle, a study in Nature Communications shows that pasteurisation of cows’ milk should effectively inactivate the virus, but that it remains infectious in unpasteurised milk. https://go.nature.com/3WRQ8fb 🧪

09.02.2025 17:36 👍 78 🔁 30 💬 6 📌 8