Carlos G. Ardanaz

Fat sensory cues in early life program central response to food and obesity - Nature Metabolism Non-nutritive sensory components of high-fat diet, such as bacon flavour, are sufficient to impair metabolic health in offspring in mice.

You are what you eat! Actually, you are also what your mother smelled during pregnancy!🤰

👃smell of high fat diet during #pregnancy primes for #obesity in offspring

Want to know more? Full story here www.nature.com/articles/s42...

Congrats! 👏@sophiesteculorum.bsky.social @lcreimon.bsky.social

🤩 I’m beyond excited to finally share our paper! 🎉 It’s been a long journey and a true team effort. Congratulations to our outstanding first authors, @lcreimon.bsky.social and Ayden Gouveia, and to all of the co-authors who made this possible 🙌!

www.nature.com/articles/s42...

Seguro! Con un poco de suerte, incluso en ambas, ya hablaremos 😉 que todo siga genial por allí!

Sooo happy for you Jonna, more than deserved, congratulations!! 😄

Thanks @thetransmitter.bsky.social and to my lab for brightening my week with this rising stars in neuroscience award!! Wish I could be in #sfn to celebrate in the sun.

Wonderful list of people: www.thetransmitter.org/early-career...

I'm more than psyched to share that my PhD paper is now out in Neuron! It's also my first paper as both first author and corresponding author, which means even more to me!

Thank my partner Chi-Chieh for her contribution to the most adorable ever graphic abstract 🥰

Go ahead and apply to the @cga-age.bsky.social ⚡⚡

We are looking for a PhD student
www.ageing-grad-school.de/phd/host-lab...

Understanding the Brain's Response to Motherhood Silvana Valtcheva's research group studies neuroplasticity in the maternal brain during the postpartum period.

www.sf.mpg.de/2112068/Silv...

New paper live!

Lots of us assumed that synaptic transmission decreases after energy shortage due to direct neuronal failure. But... Is that the case?

Spoiler: no! It's astrocytes guiding them! ⭐

Check the full study with @maitesolas.bsky.social & others:

www.aginganddisease.org/EN/10.14336/...

PAPER ALERT!📣📣
Low brain glucose?
It’s not just neuron starvation.
Astrocytes sense, respond, and regulate synapses.
GLUT1 in astrocytes is a key player in protecting the brain from metabolic stress.
Check out our full study with @cgardanaz.bsky.social

www.aginganddisease.org/EN/10.14336/...

Absolutely mindblowing work, Dio! Congratulations to you and all people involved, so much looking forward to reading it in detail!

A simple action reduces high-fat diet intake and obesity in mice Diets that are high in fat cause overeating and weight gain in multiple species of animals, suggesting that high dietary fat is sufficient to cause ob…

This was a really fun project: We blocked obesity in mice by making them do a tiny bit of work for their food. www.sciencedirect.com/science/arti...

Our new preprint: 𝐅𝐞𝐚𝐭𝐮𝐫𝐞-𝐬𝐩𝐞𝐜𝐢𝐟𝐢𝐜 𝐭𝐡𝐫𝐞𝐚𝐭 𝐜𝐨𝐝𝐢𝐧𝐠 𝐢𝐧 𝐥𝐚𝐭𝐞𝐫𝐚𝐥 𝐬𝐞𝐩𝐭𝐮𝐦 𝐠𝐮𝐢𝐝𝐞𝐬 𝐝𝐞𝐟𝐞𝐧𝐬𝐢𝐯𝐞 𝐚𝐜𝐭𝐢𝐨𝐧.

We describe how the LS guides defensive responses by forming critical computations built from functionally and molecularly distinct cells and their afferent inputs.

www.researchsquare.com/article/rs-6...

A food-sensitive olfactory circuit drives anticipatory satiety - Nature Metabolism The authors describe a sensory circuit involving the medial septum (MS), where MS glutamatergic neurons integrate food odours to prime satiety and regulate nutrient intake.

📢 🤩Excited to share our latest paper👃🧠! Huge thanks to the amazing first author @janice-bulk.bsky.social‬ and all co-authors, especially @andreas-t-schaefer.bsky.social and ‪@tobiasackels.bsky.social‬ 🙌! ‬‬
www.nature.com/articles/s42...

A food-sensitive olfactory circuit drives anticipatory satiety - Nature Metabolism The authors describe a sensory circuit involving the medial septum (MS), where MS glutamatergic neurons integrate food odours to prime satiety and regulate nutrient intake.

My first first-author paper is live - this is amazing!! 🤩
Check it out in Nature Metabolism: www.nature.com/articles/s42...
I can't thank my co-authors and everyone who helped make this happen enough!
@sophiesteculorum.bsky.social @mpi-metabolism.bsky.social

A food-sensitive olfactory circuit drives anticipatory satiety - Nature Metabolism The authors describe a sensory circuit involving the medial septum (MS), where MS glutamatergic neurons integrate food odours to prime satiety and regulate nutrient intake.

Exciting news from @sophiesteculorum.bsky.social Lab!🤓

👃🧠 Smelling food primes your brain for satiety.
Find out more in 🧵 or under 🔗 www.nature.com/articles/s42...

Congrats to @sophiesteculorum.bsky.social , first author @janice-bulk.bsky.social and all contributing authors!

Obesity dysregulates feeding-evoked response dynamics in hypothalamic satiety neurons Melanocortin-4 receptor-expressing neurons in the paraventricular nucleus of the hypothalamus (PVHMC4R) integrate hunger-promoting and hunger-suppressing signals to regulate satiety. Food consumption-...

🚨 Paper alert!
📣 We found abnormal feeding-related neural responses in satiety-promoting, MC4R-expressing neurons in the mouse paraventricular hypothalamus (PVH-MC4R) following diet-induced obesity. www.biorxiv.org/cgi/content/... ​​ #obesity #feedingbehaviour #obesityresearch #neuroscience

Last week I had the pleasure to attend and present a poster at the GRC Modulation of Neural Circuits and Behavior. Unbeatable sharing of science, companionship... and breathtaking venue catalyzing all of it!

🚨 Preprint alert! 🚨
Can mice estimate the distance to an odour source?
New work led by Cristina Marin and colleagues, jointly supervised by @andreas-t-schaefer.bsky.social at the @crick.ac.uk and myself.

Spoiler alert: Yes, they can!

Read the paper here: bit.ly/43A9tF9
Short 🧵 below

First post has to be this: