SPP2225

Robust isolation of primary ovine monocytes for reservoir host cell-specific infection studies - PubMed No widely available ovine monocyte/macrophage cell system exists. We present an affinity magnetic separation method combining gradient separation and magnetic bead selection to isolate pure primary ovine monocytes from blood, yielding large quantities of viable primary macrophages suitable for micro …

The EXIT Coordination warmly congratulates Michael Knittler, Bidiepta Saha and their colleagues on their brand-new paper — check it out!
pubmed.ncbi.nlm.nih.gov/41740799/

Congratulations on this excellent article!!!👌

🚨 New preprint!

Together with @carobarisch.bsky.social lab, we investigated how intracellular compartmentalization shapes lipid acquisition in mycobacteria

Interestingly, deleting one FACL enzyme (FACL6) revealed striking compartment-dependent phenotypes 🔬

Check it out: doi.org/10.64898/202...

Offene Promotionsstelle im Bereich der #Infektionsbiologie an der @rwth.bsky.social

Safe the date - flyer for the upcoming 2nd international colloquium of the Exit priority program: 1 - 3 Sep 2026 in Bad Honnef

SAFE THE DATE
Registration details will follow.

“Pour some sugar on me”—Environmental Candida albicans isolates and the evolution of increased pathogenicity and antifungal resistance through sugar adaptation Author summary In this study, we set out to understand whether Candida albicans found in nature can be as dangerous as the strains collected from patients, and whether a diet high in sugar affects the...

Check out another brand-new publication by our EXIT members Theresa Lange, Bernhard Hube, and Sascha Brunke, together with additional co-authors, on #Candidaalbicans in PLOS Pathogens: dx.plos.org/10.1371/jour...

Pink or blue: sex determination in malaria gametocytes Sex determination in eukaryotes defines whether an organism develops as male or female and is shaped by genetic and environmental factors. In the malaria parasite Plasmodium, recent data suggest that ...

Sexual fate decision in malaria parasites - There is still so much to discover! @spp2225.bsky.social @infect-net.bsky.social

Pink or blue: sex determination in malaria gametocytes: Trends in Parasitology www.cell.com/trends/paras...

EXIT-Strategien intrazellulärer Parasiten im Visier hochauflösender Bildgebung - BIOspektrum Living inside host cells provides significant advantages for human parasites like Plasmodium and Leishmania. Nevertheless, to complete their life cycle, they must eventually exit the host cell – a critical step that represents an attractive target for drug development. However, achieving the necessary combination of high spatial and temporal resolution imaging to capture egress dynamics remains a challenge and software pipelines for data analysis need to be advanced. Addressing these challenges will be key to unlocking the exit strategies of parasites.

HOT OF THE PRESS!!
Congratulations to Gabi @gabrielepradel.bsky.social (spp2225 speaker and consortium member) and Freddy @freddyfrischknecht.bsky.social (consortium member) on their joint publication!!

Die Infektionsforscherinnen Anja Lührmann, Sandra Reuter, Gabriele Pradel und Bärbel Stecher stehen stolz vor den Werbebannern von Infect-Net, Verband Deutscher Infektionsforscherinnen.

🔎 Find us at the 77th #DGHM Meeting in #Jena! Gabriele Pradel, Anja Lührmann, Sandra Reuter, Bärbel Stecher and others are happy to tell you more about our German network for women in infection research! 💜
👩‍🔬@gabrielepradel.bsky.social @sandrareuter.bsky.social @baerboletta.bsky.social

Infect-Net Netzwerktreffen No 6️⃣!!!
Prof. Dr. Bettina Löffler lädt Infektionsforscherinnen zu unserem 6. Netzwerktreffen nach Jena ein. Direkt im Anschluss an die Jahrestagung der #DGHM.
📅 24.-25.09.2025
📍 Jena, Germany
🧬 #Sequenzierung und #Diagnostik
#InfectNet
👉 www.infectnet.org/web/blog-pos...

Big congrats to Joachim Matz from #BNITM! Joachim, also a consortium member of our EXIT Priority Programme received the #DGHM Sponsorship Award today in Jena. Keep up the great work, Joachim!

We’re excited to announce another networking stay! EXIT member PhD Stamatis Spyridonidis from Infection Biol. Unit at @rwth.bsky.social ky.social is spending an enriching period at the @maxplanck.bsky.social. Many thanks to Prof. Levashina and Dr. Suárez-Cortés for making this opportunity possible!

Participants of the method workshop in the lab

Last week was all about flow cytometry. During a method workshop at Paul-Ehrlich-Institute PEI) in Langen, participants learned a great deal. Special thanks to Ger van Zandbergen and Bang Tam Tran (Jenny) from the PEI, who made it all possible.

Guest student Felix Müller in cell culture lab of the JRG Molecular Parasitology Group at the BNITM in Hamburg.

Felix Müller from Infection Biology Unit - @rwth.bsky.social RWTH Aachen has started his network stay at the @bnitm.bsky.social BNITM in the lab of JRG Molecular Parasitology Group. He is already doing an excellent job in cell culture. Many thanks to Joachim Matz and his team for welcoming Felix!

We had two exciting days of the @spp2225.bsky.social EXIT workshop @dfg.de @rwth.bsky.social in Aachen. We thank all friends of intracellular pathogens for joining!

The @spp2225.bsky.social EXIT-Workshop @dfg.de @rwth.bsky.social in Aachen was a big success. I thank our keynote speakers Markus Ganter and Joel Vega-Rodriguez for the exciting talks!

Hope y'all enjoyed Johannes Sonnberger's and Theresa Lange's presentations at the @spp2225.bsky.social meeting as much as we have! 😊 Both presented their work on #Candida #albicans' and Candida glabrata's interaction with macrophages. 🍄🧫🔬

@leibniz-hki.de
@jsmc-info.bsky.social

Our EXIT Statusworkshop just started and we are excited for two days of fascinating talks!

At this weeks #DGP conference in #Würzburg, we had an exciting EXIT session!

Caroline Barisch - Wissenschaft ist wie ein Smoothie: Die Vielfalt macht's! YouTube video by Infect-Net TV

👩‍🔬👨🏻‍🔬👩🏿‍🔬👩🏼‍🔬👨🏾‍🔬 Wissenschaft profitiert von #Diversität, sagt Professorin Dr. Caroline Barisch @carobarisch.bsky.social und fordert gleiche Chancen für alle. Die Mikrobiologin vom @fzborstel.bsky.social, dem @cssbhamburg.bsky.social und der @uni-hamburg.de im #Interview auf YouTube:
👉 youtu.be/yWuOc1bQpbg?...

Don't forget to register for our SPP2225 Statusworkshop in May! A great opportunity to meet EXIT colleagues and discuss projects.
www.spp2225.rwth-aachen.de/cms/spp2225/...

EXIT SPP 2225 – exit strategies of intracellular pathogens YouTube video by SPP 2225

Check out this brand new EXIT video! 🎥🎬
Starring: Plasmodium in the role of the villain and the @freddyfrischknecht.bsky.social Lab in the role of the superheroes! 🦸🏻‍♀️

youtu.be/0D1-gFO1dag

Jetzt anmelden: Am 24.3.25 findet Online & am @cssbhamburg.bsky.social die Tagung "#Tuberkulose aktuell" statt. Veranstalter sind: @fzborstel.bsky.social , Deutsches Zentralkomitee zur Bekämpfung der #Tuberkulose (DZK) & Robert Koch-Institut (RKI)
Infos&Anmeldung: fzb-veranstaltungen.de/tba-2025

Reinvigorated global efforts needed to curb rising malaria threat New data from the World Health Organization (WHO) reveal that an estimated 2.2 billion cases of malaria and 12.7 million deaths have been averted since 2000, but the disease remains a serious global h...

The #WorldMalariaReport2024 is out!

Since 2000, 2.2 billion cases and 12.7 million deaths have been averted worldwide.

But #malaria is still a threat in 2023: 263 million cases, 597,000 deaths, 95% of deaths occur in Africa. It is time to step up!

Via @who.int ➡️ www.who.int/news/item/11...

Our new banners have arrived! 😍 Keep your eyes open for them so you don't miss any EXIT sessions at conferences!
#microbiology #parasitology #lifesciences #molecularbiology

Please join us Friday 12th at noon EST for Dr. @zamanian.bsky.social seminar at Parasite hour with #PeersInParasitology where he will share his recent work on new targets and strategies for helminth control.
Need a zoom link? Register here: iu.zoom.us/webinar/regi....

EastBio: Keeping up with the Joneses: how do trypanosome parasites adapt to coinfection with other trypanosomes? at University of Edinburgh on FindAPhD.com PhD Project - EastBio: Keeping up with the Joneses: how do trypanosome parasites adapt to coinfection with other trypanosomes? at University of Edinburgh, listed on FindAPhD.com

🚨 Multiple #parasite -based PhD opportunities from the EastBio Doctoral Training Programme at Edinburgh Uni! 🚨

- Deadline for all are the 17th Jan '25

1. Trypanosoma co-infections: tinyurl.com/vyv855kw
2. Mitochondrial genome complexity in #trypanosoma: tinyurl.com/c6hk652f

#Parasitology #ntds

This week, eight SPP students participated in the #electronmicroscopy method workshop in #Osnabrück at the #CellNanOs! 🔬🧫 Looks like they had a great week 👩‍🔬👨‍🔬🍔
#pathogens #microscopy #PhD #PhDlife #scanningelectronmicroscopy #transmissionelectronmicroscopy

Hello Bluesky! 👋🦋
With this account we will keep you up to date about the activities of the SPP2225.
#pathogens #parasites #bacteria #candida #molecularbiology #science #malaria #toxoplasma #mycobacterium #lifesciences
@dfgpublic.bsky.social @gabrielepradel.bsky.social @carobarisch.bsky.social