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Ulvmar lab

@ulvmarlab

My team aims to expand the current knowledge about the lymph node vascular specialization and its changes in cancer & in aging -https://www.uu.se/en/department/medical-biochemistry-and-microbiology/research/ulvmar-maria - #lymphatics #metastasis #stroma

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21.03.2025
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Latest posts by Ulvmar lab @ulvmarlab

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Intestinal lymphatic vasculature is functionally adapted to different drainage regions and is altered by #helminth infection. From Jorden Lane, Daria EsterhΓ‘zy and colleagues: rupress.org/jem/article/...

πŸ“˜ In our #Lymphatics collection: rupress.org/jem/collecti...

01.03.2026 09:01 πŸ‘ 4 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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Lymphatic Vessels in Health and Disease 2026 | Journal of Experimental Medicine | Rockefeller University Press Advertisement

See our collection of the latest discoveries in lymphatic biology: rupress.org/jem/collecti...

26.02.2026 15:30 πŸ‘ 7 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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Registration is open for the AngioScience Conference (19-22 Sept) and Young Investigators Meeting (18-19 Sept) a.k.a. the Kloster Seeon meeting

Meeting website: www.vwfb.de

24.02.2026 15:10 πŸ‘ 7 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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Aggressive oral cancer can be identified at an early stage by changes in lymphatic vessels Oral cancers with a high risk of recurrence can be identified at an early stage by examining the lymphatic vessels of the tumour.

Oral cancers with a high risk of recurrence can be identified at an early stage by examining the lymphatic vessels of the tumour. The high number of proliferating lymphatic vessels predicted cancer recurrence and death better than any other previously known risk factor for oral cancer.
#MedSky

18.02.2026 11:56 πŸ‘ 5 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Pericytes orchestrate a tumor-restraining microenvironment in glioblastoma - Nature Communications Improved understanding of the tumor ecosystem in glioblastoma is critical for developing new treatment strategies for the disease. Here, the authors identify pericytes as an active paracrine signaling...

New paper alert 🚨
We are delighted to present our latest paper in @natcomms.nature.com through fabulous work from co-first authors Sebastian Braun and Paulina Bolivar! Big thanks to all expert collaborators for taking this long journey with us!
Tweetorial in comments 🧡
www.nature.com/articles/s41...

09.12.2025 17:05 πŸ‘ 14 πŸ” 6 πŸ’¬ 1 πŸ“Œ 0
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🌟14th EFIS-EJI TATRA Immunology Conference
πŸ’‘Proudly supported by #EFIS and @eurjimmunol.bsky.social
🀝organized by the πŸ‡¦πŸ‡Ή,πŸ‡¨πŸ‡Ώ+πŸ‡ΈπŸ‡° Immunological Societies
πŸ“šunites Europe’s rising #immunology stars since 1994
πŸ‘‰ tatra.img.cas.cz

Be part of this community shaping the future of immunology & spread the word!

21.01.2026 08:38 πŸ‘ 7 πŸ” 7 πŸ’¬ 1 πŸ“Œ 3
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Today is #WorldCancerDay

~1 in 5 people will develop #cancer in their lifetime

Each diagnosis affects not just one person, but families, communities, and futures

Grateful today for patients, clinicians, researchers & advocates - and to appreciate that progress depends on acting together

#WCD2026

04.02.2026 11:45 πŸ‘ 15 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0

A key finding of our last study is that soluble and immobilized CCL21 gradients cooperate to fine-tune different steps of lymphatic migration, revealing a new layer in leukocyte guidance.

This work was only possible thanks to an amazing team effort!

04.02.2026 08:29 πŸ‘ 6 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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uPA-mediated remodeling of CCL21 gradients regulates lymphatic migration of dendritic cells. New study from Victor Collado-Diaz, Maria-Nefeli Christakopoulou, Philipp Schineis, Cornelia Halin @halinlab.bsky.social @ethz.ch and colleagues: rupress.org/jcb/article/...

#Immunology #Migration #motility

03.02.2026 15:30 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1
Figure 2 The dimensions of cancer
CREDIT Hanahan - Cell.

Figure 2 The dimensions of cancer CREDIT Hanahan - Cell.

An update to the Hallmarks of Cancer framework for understanding (and researching) what causes human cancers. spkl.io/63321Aqwbc

Douglas Hanahan
@cp-cell.bsky.social

29.01.2026 17:00 πŸ‘ 21 πŸ” 10 πŸ’¬ 0 πŸ“Œ 10
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Fibroblastic reticular cells direct theΒ initiation of T cell responses via CD44 - Nature CD44 expressed by fibroblastic reticular cells in secondary lymphoid organs regulates trafficking of dendritic cells, and thus has an essential role in the priming of T cells and the adaptive immune response.

Nature research paper: Fibroblastic reticular cells direct the initiation of T cell responses via CD44

go.nature.com/4qxGBXl

27.01.2026 09:08 πŸ‘ 11 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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Fibroblastic reticular cells direct the initiation of T cell responses via CD44 @nature.com @the-de-lab.bsky.social
www.nature.com/articles/s41...

21.01.2026 18:06 πŸ‘ 10 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0
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Convergent evolution of scavenger cell development at brain borders - Nature Transcription factor osr2 is identified as a specific marker and regulator of mural lymphatic endothelial cell (muLEC) differentiation and maintenance, and muLECs and border-associated macrophages sha...

We’re delighted to see this out today! Latest work from the lab reveals insights into the evolution of brain immunity and the developmental and evolutionary plasticity of lymphatic endothelial cells.
www.nature.com/articles/s41...

21.01.2026 20:41 πŸ‘ 76 πŸ” 25 πŸ’¬ 13 πŸ“Œ 1
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Spatial and temporal dynamics of cancer-associated fibroblast niches in breast cancer - Breast Cancer Research Breast Cancer Research - Cancer-associated fibroblasts (CAFs) are the main constituents of the tumor microenvironment. Several studies have delineated CAF heterogeneity in different types of...

New paper out from the @kpietraslab.bsky.social lab.
I am happy to share that my first-author paper is now published. We map the spatial and temporal dynamics of cancer-associated fibroblasts in breast cancer using integrated spatial proteomics and transcriptomics.
link.springer.com/article/10.1...

17.01.2026 12:04 πŸ‘ 20 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0
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Postdoctoral Fellowships at Uppsala University - 2026 - Novo Nordisk Fonden

Danish PhDs - possibility to join Uppsala University as postdoc! Deadline 29th of Jan - My lab has an open project for a candidate who wants to study how the specialized vascular and stromal cells in lymph nodes shape the immune response in aging & cancer.
novonordiskfonden.dk/en/grant/pos...

08.01.2026 13:35 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Oscillatory shear-activated mTORC1 in Lymphatic Valve Morphogenesis & Homeostasis

Adult 🐭mesenteric Lymphatic Valve EC is more proliferative than capillary EC, indie of VEGFA/C

Flt4+ LEC Tsc1 KO in P1-5🐭➑️⏫Valve size/density at P10

@petrovalab.bsky.social #JCB 2023
rupress.org/jcb/article/...

04.01.2026 11:49 πŸ‘ 9 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
Tattoo ink induces macrophage death.

Tattoo ink induces macrophage death.

One of the most-viewed PNAS articles in the last week is β€œTattoo ink induces inflammation in the draining lymph node and alters the immune response to vaccination.” Explore the article here: https://ow.ly/zhn450XGvmW

For more trending articles, visit https://ow.ly/7BgF50XGvmV.

10.12.2025 00:30 πŸ‘ 19 πŸ” 8 πŸ’¬ 0 πŸ“Œ 1
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Comparative analysis of commercial Imaging-based #SpatialTranscriptomics methods

Xenium
CosMx 1k
MERSCOPE

Tissue Microarray
17 tumor+16 normal tissue

Transcript count
vs Reference RNAseq
Segmentation accuracy
Cell type annotation

#NatComms 2025
www.nature.com/articles/s41...

01.12.2025 12:52 πŸ‘ 19 πŸ” 9 πŸ’¬ 0 πŸ“Œ 0
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Kurz, LΓΌtge, Ludewig et al. elucidate the ontogeny of fibroblastic reticular cells and vascular smooth muscle cells in mouse lymph nodes from proliferating, CCL19-expressing progenitors & highlight the close lineage relationship of the progeny in the perivascular niche rupress.org/jem/article/...

26.11.2025 18:02 πŸ‘ 6 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Membership - European Vascular Biology Organisation EVBO needs your support to further expand its activities and invites you to become a member.EVBO develops scientific, educational, training and networking activities to potentiate vascular biologists…

Big news, EVBO community!
Our BLACK FRIDAY membership deal is live until 31 Dec 2025:
πŸ”Ή 3-year full membership: €120
πŸ”Ή PhD/postdoc: €75
Join now ➜ evbo.org/index.php/me...

Plus, members get access to 3 exclusive vascular biology workshops in 2026. Don’t miss out!

27.11.2025 11:48 πŸ‘ 2 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0

It was a great pleasure to be a part of this new study from @halinlab.bsky.social focusing on the #Lymphatics in human skin!

16.11.2025 00:14 πŸ‘ 15 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0
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Our @natcomms.nature.com paper is finally out! πŸš€ rdcu.be/eQnYW
Using scRNA-seq and Visium HD, we mapped lymphatics in metastatic lymph nodes from breast cancer patients and discovered striking lymphatic remodeling that shapes subsequent metastasis.
Massive thanks to all collaborators!!!

17.11.2025 17:47 πŸ‘ 7 πŸ” 1 πŸ’¬ 1 πŸ“Œ 1
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Do Not miss this great @navbo.bsky.social online eventπŸ˜†

Specification of Endothelial Cell Phenotypes

Organized by Dr. Ralf Adams @ralfhadams.bsky.social
& Dr. Vicki Bautch

Abstract deadline November 20

members.navbo.org/calendar-of-...

13.11.2025 19:50 πŸ‘ 15 πŸ” 6 πŸ’¬ 1 πŸ“Œ 0

Check out our new study in @jem.org on #Lymphatics using #SingleCell and #3DImaging in human skin, revealing new features of the lymphatic vascular system in #HumanBiology!

15.11.2025 22:25 πŸ‘ 9 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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Reformation of science publishing: the Stockholm Declaration | Royal Society Open Science Science relies on integrity and trustworthiness. But scientists under career pressure are lured to purchase fake publications from β€˜paper mills’ that use AI-generated data, text and image fabrication....

Reformation of science publishing: the Stockholm Declaration
A call to action for universities, academies, science organizations and funders to unite and join this effort.
Bernhard Sabel and Dan Larhammar

royalsocietypublishing.org/doi/10.1098/...

09.11.2025 20:42 πŸ‘ 81 πŸ” 44 πŸ’¬ 3 πŸ“Œ 3
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Transcriptomics- and 3D imaging-based characterization of the lymphatic vasculature in human skin. New study from Aline Bauer, Cornelia Halin and colleagues @ethz.ch: rupress.org/jem/article/...

#CardiovascularBiology #InnateImmunity #inflammation #Lymphatics

11.11.2025 14:45 πŸ‘ 10 πŸ” 3 πŸ’¬ 0 πŸ“Œ 2
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New study from Bauer, Halin et al. @ethz.ch reveals how the structure and cellular morphology of human dermal afferent lymphatic vessels differ from the current, primarily mouse tissue–based textbook description. rupress.org/jem/article/...

#Lymphatics

04.11.2025 17:00 πŸ‘ 7 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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AI chatbots are sycophants β€” researchers say it's harming science Nature - Nature asked researchers who use artificial intelligence how its propensity for people-pleasing affects their work β€” and what they are doing to mitigate it.

AI models are 50% more sycophantic than humans

go.nature.com/4ol1Quq

02.11.2025 13:31 πŸ‘ 27 πŸ” 18 πŸ’¬ 0 πŸ“Œ 4
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‼️Lymphatic Education&Research Network-GRC Scholarships‼️

LE&RN is awarding 10 Γ— $1,000 scholarships to early investigators to attend 2026 Lymphatics GRC March 1 – March 6, 2026, Lucca (Barga), Italy.

πŸ—“ Apply by Dec 8, 2025!

form.jotform.com/LERN/2026-gr...

31.10.2025 17:11 πŸ‘ 7 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0
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Why fundamental research is fundamental to progress, seeding major breakthroughs
Editorial @nature.com this week
And 7 basic science discoveries that changed the world
nature.com/articles/d41...
nature.com/articles/d41...

29.10.2025 12:58 πŸ‘ 150 πŸ” 58 πŸ’¬ 0 πŸ“Œ 2