Felix Franke's Avatar

Felix Franke

@ffranke

Retina, Neuroscience, Engineering Timing in neural systems, Axons and their transmission speed Prof@Uni Basel / IOB

192
Followers
128
Following
3
Posts
09.01.2024
Joined
Posts Following

Latest posts by Felix Franke @ffranke

Preview
In vivo single-cell gene editing using RNA electroporation reveals sequential adaptation of cortical neurons to excitatory-inhibitory imbalance The balance between excitatory and inhibitory neurotransmission is fundamental for normal brain function, yet the adaptation of individual neurons to disrupted excitatory-inhibitory balance is not wel...

Gene editing of single, targeted neurons in vivo is now feasible. We are proud to present our preprint for highly efficient single-cell electroporation using RNA. With @alex-fratzl.bsky.social, @munzlab.bsky.social, Botond Roska @iobswiss.bsky.social
#neuroskyence
www.biorxiv.org/content/10.1...

15.09.2025 09:19 ๐Ÿ‘ 51 ๐Ÿ” 19 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 4
Post image

Thrilled to share that our work is now published in Science! โœจ

We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! ๐Ÿงญ

www.science.org/doi/10.1126/...

๐Ÿงต1/

11.09.2025 20:12 ๐Ÿ‘ 175 ๐Ÿ” 72 ๐Ÿ’ฌ 8 ๐Ÿ“Œ 6
Post image

๐Ÿ‘๐Ÿง  NEW: The human retina has its own built-in timing fix!
A Nature Neuroscience study led by @ethz.ch | BEL Lab, IOB Basel, @unibas.ch shows that photoreceptor signals โ€“ even those that travel farther โ€“ arrive in sync! >https://u.ethz.ch/S4DvU
#Retina #Neuroscience #Bioengineering #ETHZurich

06.08.2025 15:10 ๐Ÿ‘ 3 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

The answer: Photoreceptors need to connect to other neurons in your eye (via yet other neurons) and those can make the connection to your brain.

These neurons are called retinal ganglion cells, the one you see in the image.

But why a ring?

28.11.2024 17:42 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 0

Why does it look like a ring?

Because it is a ring. In the very center of your eye, you only have photoreceptors to detect light!

But photoreceptors do not connect to your brain.

So how to get the information from the photoreceptors out?

28.11.2024 17:40 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 0

You are currently using them to read this text!

The image basically shows how visual information about this letter here, yes this one (and this one, too!) is traveling from your eye to your brain.

28.11.2024 17:39 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0