www.organic-chemistry.org/abstracts/li...
A photoredox three-component reaction enables the synthesis of medicinally relevant β-trifluoromethyl β-amino ketones
10.03.2026 11:23
👍 0
🔁 0
💬 0
📌 0
www.organic-chemistry.org/abstracts/li...
A photoredox three-component reaction enables the synthesis of medicinally relevant β-trifluoromethyl β-amino ketones
www.organic-chemistry.org/abstracts/li...
Binaphthyl-proline hybrid chiral ligands were used for a copper(II)-catalyzed asymmetric Henry reaction
www.organic-chemistry.org/abstracts/li...
A [3+2] dipolar cycloaddition of azine N-oxide withs carbodiimides provides 2-amino azines
www.organic-chemistry.org/abstracts/li...
A visible-light-promoted metal-free three-component decarboxylative annulation provides 2,4-diarylquinolines from readily available α,β-unsaturated acids, aromatic amines, and α-keto acids
www.organic-chemistry.org/abstracts/li...
Sulfur alkylation of N-acyl sulfenamides with alkyl halides provides sulfilimines in good yields.
www.organic-chemistry.org/abstracts/li...
Pd-catalyzed cross coupling reactions between aryl halides and a range of aryl and benzylpotassium species
www.organic-chemistry.org/abstracts/li...
Appropriate metal halide Lewis acids act as a carbonyl activator and halogen carrier for a deoxyhalogenation of aryl aldehydes, ketones, carboxylic acids, and esters
www.organic-chemistry.org/abstracts/li...
An annulation of 2-cyanoaryl acrylamides via C=C double bond cleavage enables a facile and efficient synthesis of functionalized 4-amino-2-quinolones
www.organic-chemistry.org/abstracts/li...
Ruthenium chloride catalyzes a sustainable one-pot method for synthesizing aldehydes from benzylic or primary alkyl halides
www.organic-chemistry.org/abstracts/li...
A radical-based C-C bond scission of 1,1-disubstituted epoxides followed by demethylenation provides ketones.
www.organic-chemistry.org/abstracts/li...
A visible-light-mediated oxidative cyclization of 2-aminobenzyl alcohols with secondary alcohols provides quinolines
www.organic-chemistry.org/Highlights/2...
Douglass features Functional Group Interconversion: The Hale Synthesis of Trichostatin A
Molecule of the Week: Trichostatin A
Trichostatin A, isolated from Streptomyces hygroscopicus MST-AS5346, is a potent inhibitor of histone deacetylase.
More Info: www.organic-chemistry.org/Highlights/2...
www.organic-chemistry.org/abstracts/li...
A broad range of sulfoxides, including aryl-aryl, aryl-alkyl, aryl-alkenyl, and alkyl-alkyl sulfoxides, can be readily converted to the corresponding thioethers
www.organic-chemistry.org/abstracts/li...
Triphenylphosphine catalyzes a coupling of maleimides with 1,3,5-triazinanes
www.organic-chemistry.org/abstracts/li...
Hydrobromination reactions of alkenes with TMSBr and oxygen as common reagents provide the anti-Markovnikov product in the presence of parts per million amounts of a Cu(I) species
www.organic-chemistry.org/abstracts/li...
The combination of CuI/6-hydroxy picolinohydrazide catalyzes a coupling of (hetero)aryl chlorides with anilines at 100 °C
www.organic-chemistry.org/abstracts/li...
An iridium-catalyzed diastereo- and enantioselective [4 + 1] cycloaddition reaction of hydroxyallyl anilines with sulfoxonium ylides provides 3-vinyl indolines
www.organic-chemistry.org/abstracts/li...
An unprecedented cobalt-catalyzed highly site-, diastereo-, and enantioselective protocol for stereoselective formation of nucleophilic allyl-Co(II) complexes
www.organic-chemistry.org/abstracts/li...
A benziodazole-type O2NO-I(III) compound reacts as a nitrating reagent with a series of electron-rich arenes
www.organic-chemistry.org/abstracts/li...
A simple, mild, metal-free catalytic protocol for an efficient conversion of amides to amines at r.t. uses the stable tetrabutylammonium difluorotriphenylsilicate in combination with silanes
www.organic-chemistry.org/abstracts/li...
Trifluoromethylsulfonyl-pyridinium salt (TFSP) is an efficient, solid trifluoromethylation reagent
www.organic-chemistry.org/abstracts/li...
A nickel-photocatalyzed cross-coupling reaction between enol silyl ethers and CF3-substituted alkyl bromides
www.organic-chemistry.org/abstracts/li...
A direct allylic C-H bond activation of α-methylstyrene derivatives with sulfonylhydrazines provides allylic sulfones
www.organic-chemistry.org/abstracts/li...
A green electrochemical method provides 2-amino-1,3-benzoxazine derivatives via TBAI-mediated desulfurative cyclization of isothiocyanates and 2-aminobenzyl alcohols.
www.organic-chemistry.org/abstracts/li...
Dinitro-5,5-dimethylhydantoin (DNDMH) serves as an arene nitration reagent with good functional group tolerance.
www.organic-chemistry.org/abstracts/li...
Formation of alkyl radicals via activation of alkyl bromides through cobalt/iridium catalysis enables a reductive radical conjugate addition under mild and less toxic conditions.
www.organic-chemistry.org/abstracts/li...
The use of ruthenium catalysts with six-membered N-heterocyclic carbene (NHC) ligands enables a successful synthesis of five- and six-membered fluorinated olefin rings.
www.organic-chemistry.org/abstracts/li...
An efficient copper-catalyzed cross-coupling of allyl phosphate with 2-fluoro-2-(trimethylsilyl)acetate
www.organic-chemistry.org/abstracts/li...
Cu-catalyzed allylation of aldehydes or ketones with α-vinyl allylboronate provides secondary or tertiary δ-vinyl-homoallylic alcohols with high E-selectivities.