Lydia Lynch

Obesity, adipose tissue, and systemic metabolism in cancer on the first session of #CFM_MetCanc. 
Speakers: 

Paul Cohen @rockefeller.edu 
Stephan Herzig @helmholtzmunich.bsky.social
@lydialynch.bsky.social @ludwigcancer.bsky.social

✍️ https://bit.ly/45jaORu 

Sponsored by @caixaresearch.bsky.social

Our next #FusionMetabolism meeting unites researchers across the spectrum; from investigating individual molecules to carrying out population studies & clinical trials👩‍🔬

Submit by 13 April 2026 to join the line up ➡️https://bit.ly/45CT3MY
@petemullen.bsky.social @annakrook.bsky.social

😆😆😆😆 👕👉

Looks like it to me 😆

@zuri so delighted for you, congratulations!

Super brilliant talk by Shruti @drshrutinaik.bsky.social visiting us in Princeton today 🐅 @princetonmolbio.bsky.social on new frontiers for the immune system in health, and co-opted in disease

He’s a doctor 🎉 Congratulations Dr Martin Brennan @princetonmolbio.bsky.social @tbsi-tcd.bsky.social We’re going to miss him so much! Onwards and upwards

Metformin's Weight Loss Effect Linked to "Anti-Hunger" Molecule Produced During Exercise A new study conducted by researchers at Stanford Medicine and Harvard Medical School has found that the diabetes medication metformin causes weight loss

Diabetes drug metformin causes weight loss by triggering the production of an "anti-hunger" molecule called lac-phe, also produced after vigorous exercise. #Metformin #WeightLoss #LacPhe #GutBrainConnection

And thank YOU Amanda for all your help on this team project for many years! It takes a village (to publish these days)

And funding from @nih niaid @themarkfdn.bsky.social @ludwigcancer.bsky.social @irishresearchcouncil

Special thanks to @hannahprendeville.bsky.social @britta, @clairemci.bsky.social @roisin @ayantu and collaborators @edchouchani, @marciahaigis, @susankaech @evannamills

The source of dietary fat influences anti-tumour immunity in obese mice - Nature Metabolism This study shows that animal-based high-fat diets accelerate tumour growth and impair anti-tumour response to melanoma in obese mice, whereas plant-based high-fat diets do not.

This was a labor of love requiring lots of teamwork over years, repeating in 3 locations! Thanks to all the lab over the years, giving their time generously to this team project, & our wonderful collaborators. The source of fat matters for anti-tumor immunity 🐄🐖🧈🌴🫒🥥
www.nature.com/articles/s42...

Happy summer from Princeton. Feeling very lucky ☘️🐅

Ascites-derived Lipid Uptake Drives NK Cell Dysfunction in Ovarian Cancer Major Finding: Lipids derived from ascites are taken up by NK cells and drive NK cell dysfunction in ovarian cancer. Concept: Polar lipids such as phosphatidylcholine disrupt NK plasma membrane order ...

ICYMI: Ascites-derived Lipid Uptake Drives NK Cell Dysfunction in Ovarian Cancer, a #ResearchWatch summary of a new study by @karen--s.bsky.social, @lydialynch.bsky.social, and colleagues at @ludwigcancer.bsky.social @princetonmolbio.bsky.social

aacrjournals.org/cdnews/news/...

Disrupting the balance between activating and inhibitory receptors of γδT cells for effective cancer immunotherapy Nature Reviews Cancer - In this Review, Beringer and colleagues highlight how future strategies for developing immunotherapies using γδT cells and their receptors will depend on creating...

www.nature.com/articles/s41...

@jkuball.bsky.social @sotnom.bsky.social @lydialynch.bsky.social @labminguet.bsky.social

With nearly all of Harvard Chan School’s direct federal grants terminated, we are relying on philanthropy to power our research and support our educational programs. Every gift, regardless of size, advances our vision of health, dignity, and justice for every human. Support our work: hsph.me/whygive

Our paper @sciimmunology.bsky.social shows certain lipids are responsible for the immunosupression of ascites & propose blocking lipid uptake thru SCARB1 may help immunotherapy in ovarian cancer. Wonderful to collaborate with Donal Brennan, Marcia Haigis & super postdoc @karen--s.bsky.social

Researchers led by Ludwig Princeton’s @lydialynch.bsky.social report that certain fats in ascites fluid—which accumulates as ovarian cancer spreads from the ovaries into the abdomen—sabotage anti-tumor immune responses and show how this effect might be blocked for immunotherapy. bit.ly/4jGuUtU

Wooo congrats Kivanc! Totally deserving winner of this great community award 🏆 Sad to miss a great meeting!

A beautiful day in Princeton @princeton.bsky.social to host our Ludwig Distinguished speaker Dr Kivanc Birsoy from Rockefeller @ludwigcancer.bsky.social

Delighted to have taken part in this project that was published today led by Tomas Ryan’s lab @tjryan.bsky.social @tcddublin.bsky.social @tbsi-tcd.bsky.social ….. mice remember cold 🐭📝❄️

Claudia Scheinbaum, President of Mexico, in the centre of the image in a purple dress on International Women’s Day, 2025. A search around on google fails to turn up an image credit unfortunately, I found it on Reddit: https://www.reddit.com/r/AccidentalRenaissance/s/MGhF9O80FL

HANG IT IN THE LOUVRE.

(President of Mexico on International Women’s Day)

NIH budget: $ 48b
Musk wealth: $351b

Both are mostly funded by your tax dollars

But only one might save your life
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Sources:
www.nih.gov/about-nih/wh...

Search results: elon musk net worth g.co/kgs/6c8YEuB

@standupforscience.bsky.social

Thank you to our colleagues in France ❤️🇫🇷❤️🇺🇸❤️ #standupforscience

Thank you to our colleagues @pasteur.fr Paris 🇫🇷🥼🧪 #standupforscience

Thank you to our colleagues in Geneva #standupforscience

Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter
www.nytimes.com/2025/03/01/u...

So happy to have @aiinglim.bsky.social as a colleague at Princeton! Her immunology is so exciting and original 😍 Great talk at Princetons ‘Quantitative Immunology’ Symposium today @princetonmolbio.bsky.social

First measles death in Texas. Unfortunately, not surprising. Number of cases likely to increase and we may see more deaths. A tragic, preventable death of a school aged child. But the outbreak is called "not so unusual" by RFK. Simply not true. This is both unusual AND preventable. #vaccineswork

Congratulations to the amazing @karen--s.bsky.social ! And many thanks to @irishcancersociety and Prof Donal Brennan in @ucddublin.bsky.social for continued collaboration on gynaecological cancer research