Love the level of creativity you are putting into planning and designing these!
Excellent opportunity!
17.02.2026 17:14
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Love the level of creativity you are putting into planning and designing these!
Excellent opportunity!
๐ฅEssential Tremor-2026 update!
๐Current RCT evidence using at least a month of follow-up is insufficient to support ET medications!
๐ Better trials needed!
Wonderful work by DeepaDash
madam and team!
Full paper-https://doi.org/10.1002/mds.70184
A visual summary ๐
#EBM
๐ฅA new ray of hope for PPMS!
The FENtrepid results comparing Fenebrutinib vs ocrelizumab are so encouraging!
The wonderful podcast๐
ectrims.eu/podcast/episodโฆ
And a summary ๐
๐ฅOCEANIC charts a safer course in Stroke prevention๐
๐Asundexian 50 mg OD โ ischemic stroke 6.2% vs 8.4% (HR 0.74, 95% CI 0.65โ0.84, p<0.001)
๐No significant increase in major/clinically relevant non-major/minor intracranial bleeding!
๐
clinicaltrialresults.org
Summary ๐
๐ฅAn "OPTION" of thrombolysing non LVOs beyond 4.5hrs with Tenecteplase with perfusion imaging โ
Hot off the JAMA press!
๐๐ Non-LVO stroke (4.5โ24h):
๐Tenecteplase โ mRS 0โ1 RR 1.28 (95%CI 1.04โ1.57)
โ ๏ธ sICH 2.8% vs 0%.
Full paper:10.1001/jama.2026.0210
A visual summary ๐
๐ฅEMPHASIS now on the Neurovascular Unit ๐ค
๐ง Neuroprotection โ neurons alone.
๐ Minocycline within 72 h of ischaemic stroke increased mRS 0โ1 at 90 days (52.6% vs 47.4%; adjusted RR 1.11, 95% CI 1.03โ1.20)
Check out ๐
doi.org/10.1016/S014...
A summary ๐
Very true ๐
Evidence is one thing, real-world availability and skill mix another.
Highlights why ED migraine care needs local adaptation!
โHow do you manage acute migraine attacks in the ED? ๐
The AHS guidelines are here!
IV prochlorperazine & GON block = top choices.
IV Opioids & IV paracetamol โ
-A look at the full paper-https://doi.org/10.1111/head.70016
-And the visual summary here๐
#Migraine
๐คShould you thrombolyse an Acute CRAO?
๐ดThe TenCRAOS tells us not to!
Have a look at the full trial results:๐
www.nejm.org/doi/full/10....
And a summary here๐
๐ฅ๐ง The much needed 2026 AHA/ASA guidelines on Acute Ischemic Stroke are out!
Check out the paper๐
doi.org/10.1161/STR....
and key takeaways:-
๐ค Do steroids improve outcomes in adult HSV encephalitis?
๐DexEnceph RCT (n=94, UK): dexamethasone + acyclovir vs acyclovir alone.
๐No improvement in verbal memory at 26 weeks (ฮ 1.77; p=0.76).
โSteroids safe, but no cognitive benefit.
Link:https://doi.org/10.1016/S1474-4422(25)00454-5
๐ฅ Hot off Cell Press! ๐ง ๐ฃ๏ธ
Did you know the cerebellum has a language-selective region?
This new fMRI study(n=800+) says so!
๐LangCereb3 is highly language-selectiveโ
๐คTime to start looking for LangCereb3 aphasias?
Check this out๐
doi.org/10.1016/j.ne...
#Cerebellum
#Aphasia
Such an interesting observation! It's amazing how something as small as a space can make or break the Excel-ence of a spreadsheet.
@amahajanmd.bsky.social @michaelokun.bsky.social @oligoclonalband.bsky.social @staceylclardy.bsky.social @caseyalbin.bsky.social @deweylovesneuro.bsky.social @mettermd.bsky.social @luschkaa.bsky.social
๐Honest answersโผ๏ธ
๐ฅฑ How often do you assess fatigue in individuals with Parkinsonโs Disease(PD)โ
โ Do you think everyone who feels tired is truly fatiguedโ
๐ Did you know PD has a unique "Park Fatigue" subtypeโ
๐Check out our latest paper. #Neurosky #Fatigue
journals.lww.com/aomd/fulltex...
@amykunchok.bsky.social @headachemd.bsky.social
@birdreader.bsky.social @katha1970.bsky.social
@zachlondon.bsky.social @luschkaa.bsky.social @rohitmarawar.bsky.social @amahajanmd.bsky.social
@caseyalbin.bsky.social @anisheeundavia.bsky.social @staceylclardy.bsky.social @oligoclonalband.bsky.social @teachplaygrub.bsky.social @ajlees.bsky.social @deweylovesneuro.bsky.social @mettermd.bsky.social
8/
โWhat are the causes of this radiological findings
โHow should this case be managed-He is on steroids/Azathioprine stopped he has leucopenia 3000 due to the drug.
โผ๏ธThis guy isn't agreeing for a biopsy
7/May 2023-Dec 2024
Comes with progression of right hemiparesis and vision loss.
Currently-
๐VA-5/60,6/60
R UMN facial palsy
R Profound Hearing loss
Power-Right UL and LL-4/5
And we do the imaging and get this...
6/๐ง CSF:Cells-30(85%Lympho) Prot-93, Sugars-N TBPCR-Neg
IgG4-Neg
ANA/ANCA/ENA prof-Neg
Serum ACE-N
DSA-meningeal blush+
Given Empiric ATT+Steroids and Azathioprine.
Symptomatically improved-Ambulatory mRS-2
5/ ๐ฅAdmitted at a hospital and investigated.
Exam;CN-II R-VII,VIII inv.
Power:Upper and Lower limbs-B/L4/5.
๐ง MRI brain-Diffuse Pachymeningeal Enhancement. Nodular enhancing granulomas in b/l frontal,parietal regions๐ . Left lentiform nucleus infarct.
MRV:Chronic thrombosis of Sup Sag Sinusโผ๏ธ
4/โฉ2021:
๐Develops sudden onset Left hemiparesis with facial weakness and dysphagiaโผ๏ธ
Admitted in a nearby hospital (documents n/a) given some injectable medications. Improved over 3-4months.
โฉDec 2022:
๐Sudden onset Right hemiparesis with facial weakness and dysarthria.
3/โฉFast forward to 2020-COVID times; Less frequent OPD visits and he stops ๐ Dabigatran for over a month.
โผ๏ธIs found lying on the fields one fine morning unconscious. Brought home and then regains consciousness in a few hours. Restarted ๐ Dabigatran.
2/๐ซThis gentleman moves from hospital to hospital but to no relief and in 2014 someone gets an MRI brain with MRV (films N/A).
He says that he was given ๐Dabigatran based on his MRI report.
๐His headache and vomiting subside over 3-4months. But his vision loss and hearing loss persist.
๐ง Case Alertโผ๏ธ #Neurosky #Neurocase
1/๐คA 52yr old man comes in with a history of intermittent left sided headaches a/w vomiting+B/L ๐vision loss (unclear onset)+Slowly progressive hearing๐loss in right ear since 2006.
That's cool... Following the footsteps of the legendary Helen Taussig..My best wishes.
This is wonderful! So does she want to be a cardiologist?
Do you feel primary outcome assessment at 6months or 3months would have any effect on the final results?
For eg one sec outcome-Radiographic vasospasm was lower in the liberal group (risk ratio, 0.77; 95% CI, 0.63 to 0.95) which is significant.