theNiessingLabs

We are excited to share our new preprint: iCLIP3 — an improved protocol for transcriptome-wide mapping of protein–RNA interactions at single-nucleotide resolution.

Searching for a human neural cell line with greater differentiation potential than SH-SY5Y cells? Check out the human #neural #stem_cell line HNSC.100. Differentiates into astrocytes, neurons & oligodendrocytes. On #BioRxiv, we provide protocols, markers, ABs, karyotyping & RNAseq: shorturl.at/y0aJG

Merry Christmas and Happy New Year to all of you! 🎄

It was a great meeting! Thank you Michael.

Veranstaltungsplakat der 33. Vortragsreihe der UUG

Von Bio-inspirierten Technologien über medizinische & gesellschaftliche Herausforderungen bis hin zur Neurochirurgie spannt sich der Bogen der Vortragsreihe der Ulmer Universitätsgesellschaft. Eintritt frei!🆓 t1p.de/uug_33 *stg #uulm

Donation of 10.000 Euro to our lab

We are so grateful! PURA Syndrome Deutschland e.V. makes donation to support our research on #PURA syndrome at @helmholtzmunich.bsky.social, #Rare #puraperfect.

Had an exciting visit to the German University in Cairo (www.guc.edu.eg). I was impressed by how much this university contributes to mutual understanding between Europe and the Middle East through academic exchange. Much needed these days! Close collaboration with #UUlm and supported by #DAAD.

Today we launched the #PURA Biobank at @www.helmholtz-munich.de for patients with #purasyndrome. Biosamples will support research and development of treatment strategies. Big thanks to PURA Syndrome Foundation USA for your constant support! #Rare #puraperfect www.helmholtz-munich.de/en/pura-biob...

Great collaboration of Simone Heber and Anne Ephrussi with our lab on Staufen-dependent RNA localization!

Perturbing RNA localization for functional study in neurons Spatial RNA organization plays a pivotal role in diverse cellular processes and diseases, but the functional implications of spatial RNA localization remain underexplored. We present CRISPR-mediated t...

www.biorxiv.org/content/10.1...

We participated in Interact Munich 2025, where we had the opportunity to present our research through posters, connect with fellow young researchers, and attend inspiring talks. A big thank you to the organizing team for making such a fantastic event possible! #interact2025

Lab work is important but also consumes lots of energy and resources. We are the first lab at @www.helmholtz-munich.de to be awarded with the Gold level LEAF (Laboratory Efficiency Assessment Framework) certificate of the @ucl.ac.uk for our efforts to become a more sustainable laboratory!

Terrified by the global developments and current politics? We took a break from the world by attending a hip-hop dance class. Lots of excitement, confusion, and happiness. We can highly recommend it as a mental therapy...

Opinion | American Science is Under Attack (Gift Article) The Trump administration hobbles research and endangers the public health.

I Used to Run the N.I.H. Here’s What Worries Me.
www.nytimes.com/2025/02/14/o...

🚨 Early Bird Registration Closing Soon for Interact Munich 2025! 🚨

⏳ Don’t miss out! Our Early Bird pricing for Interact Munich 2025 ends on February 17th – secure your spot today and save on registration!

Check out our recent work on CDS #m6A mediated RNA decay (CMD)! Decay relies on ribosome pausing at m6A containing codons. Great collab with the Zarnack lab & colleagues. Thank you @uniwuerzburg.bsky.social , @imbmainz.bsky.social and RMap🥳

www.cell.com/molecular-ce...

Now out on bioRxiv: our collaboration with Simone Heber, Anne Ephrussi and Jeff Chao reveals how Staufen interacts with the kinesin adapter aTm1 to localize oskar mRNA in #Drosophila oocytes, modulating kinesin-1 dependent mRNA transport. #RNAsky #RNA doi.org/10.1101/2024...

EDUCATION CORNER: Molecule of the Month: Celebrating  25 Years of Storytelling and Announcing New Beginnings After a remarkable 300 columns, David Goodsell has retired from the Molecule of the Month series.  Janet Iwasa will be continuing the series for PDB-101.

After a remarkable 300 columns, David Goodsell has retired from the Molecule of the Month. We are very grateful for his service.
@jiwasa.bsky.social will continue the series, beginning with January's article on Assembly Line Polyketide Synthases
Details: cdn.rcsb.org/rcsb-pd...

🌟 Welcome to <interact> 2025 🌟
We’re thrilled to announce the most exciting student-organised scientific conference is back in 2025! 🎉

📅 Mark your calendars:
🗓️ April 3-4, 2025
📍 Venue: Biomedical Center (BMC), LMU Munich

Just beautiful! I stopped working on Drosophila development more than 20 years ago but still get excited about this organism! Great movie 🪰

Hello Bluesky 🤠
Our very first post is about our recent paper in Nucleic Acids Research: so-called PUN motifs are repetitive elements enabling proteins to catalyze #RNA folding and RNA-dependent #condensate formation ( #LLPS). 15% of human proteins contain 3 or more PUN motifs. See bit.ly/4fZ3f54.