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Karl Biggs

@karlbiggs

Cell biologist passionate about microglia, lysosomes, and extracellular vesicles. My favorite protein is alpha synuclein. UCLA [BS] -> Dartmouth[PhD] -> currently industry scientist in Boston.

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08.02.2024
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Latest posts by Karl Biggs @karlbiggs

Hello imaging friends! Does anyone know a R/FR tag that is still somewhat bright after PFA+GA fixation? I need a two color experiment, and I am already using mEos4b for the G channel. Please RT!!

15.08.2025 18:38 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Coronin1A Regulates the Trafficking of Alpha Synuclein in Microglia Microglia respond to cytotoxic protein aggregates associated with the progression of neurodegenerative disease. Pathological protein aggregates activate the microglial NLRP3 inflammasome resulting in ...

Happy to share my main project from my PhD is published and on the cover of the Journal of Neuroscience!

If you’re interested in lysosomes, Parkinson’s Disease, neuroinflammation, or EVs it might have something in it for you!

www.jneurosci.org/content/45/1...

DM for the pdf if you need access!

13.03.2025 13:10 πŸ‘ 12 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

Check out this fantastic new review on lysosome resilience mechanisms from a highly respected lysosomologist!

27.02.2025 19:42 πŸ‘ 8 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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πŸ“£ We are kicking off 2025 with a #LRRK2 webinar hosted by Luis Bonet Ponce, PhD from the Ohio State Department of Neurology at 1 pm ET. Mark your calendars!

πŸ“… 1/23
⏰ 1 pm ET
RSVP: us06web.zoom.us/meeting/regi...

17.01.2025 17:29 πŸ‘ 5 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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The censorship algorithm on Twitter reduced our audience by roughly 95%, and seriously, who does that to a wildlife biology & advocacy group ?
So we moved πŸ˜‡ over here to BlueSky

If you could, please help us regain our following
Follow
Retweet and
Repeat ;-)

Together we can change the world.

04.01.2025 17:56 πŸ‘ 22746 πŸ” 9408 πŸ’¬ 581 πŸ“Œ 332

would love to be added, thank you!

03.12.2024 01:31 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

would love to be added! thank you!

03.12.2024 01:30 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Little late but could I be added please!

03.12.2024 01:24 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0