Lucas Waltzer 's Avatar

Lucas Waltzer

@lucaswaltzer

Group leader at iGReD Clermont-Ferrand, drosophila & epigenetics, food & mushrooms https://www.igred.fr/en/team/ero-epigenetic-regulations-ontogenesis/

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16.09.2023
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Latest posts by Lucas Waltzer @lucaswaltzer

07.03.2026 19:11 👍 154 🔁 108 💬 4 📌 15
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Seven wonders of RNA modification biology This Perspective discusses seven frontiers in RNA modification research. The examples cited highlight technological advances, regulatory principles both unique and broad-spanning, and questions about how biological information is ...

This piece discusses seven frontiers in RNA modification research. The examples cited highlight technological advances, regulatory principles both unique & broad-spanning, & questions about how biological information is post-transcriptionally encoded in chemical marks comprising just a few atoms.

03.03.2026 21:36 👍 2 🔁 1 💬 0 📌 0

Connerie sans frontières ?

03.03.2026 18:58 👍 0 🔁 0 💬 0 📌 0
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Combined assembloid modeling and 3D whole-organ mapping captures the microanatomy and function of the human fallopian tube Tunable assembloid modeling and CODA tissue mapping, in tandem, design a tissue-validated in vitro model of the fallopian tube.

I think there is a need for a complete re-think for organoid modeling.

As long as the architecture of organoids that you produce is not directly compared to a 3D map of the organ (say, a fallopian tube) or disease to be modeled, it will be approximate.

More here: www.science.org/doi/full/10....

01.03.2026 20:17 👍 42 🔁 7 💬 1 📌 1

This post is definitely a milestone for Merriam-Webster

24.02.2026 19:51 👍 9 🔁 4 💬 1 📌 0

Fil RH #CNRS d’avant le week-end
#ESR

Les données 2025 viennent d’être intégrées au sein du module Zento RH et donc je vous propose quelques mises à jour des informations RH générales au CNRS.

Ne zappez pas, la suite va vous surprendre ! (oui, ici on est putaclic)
1/12

27.02.2026 12:13 👍 10 🔁 6 💬 1 📌 0

Cela doit être lié à la faillite du GIE et la reprise de personnels par les 3 tutelles...
www.unistra.fr/sites/defaul...

28.02.2026 12:57 👍 1 🔁 0 💬 0 📌 0

Scientific paper mill: the model flagged 10% of the research papers in cancer research as problematic 😱

www.bmj.com/content/392/...

26.02.2026 20:01 👍 8 🔁 1 💬 0 📌 0
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Les fausses publications scientifiques menacent de submerger la recherche contre le cancer Une étude récente pointe un chiffre alarmant : plus de 250 000 articles scientifiques liés au cancer pourraient avoir été fabriqués de toutes pièces entre 1999 et 2024.

Les fausses publications scientifiques menacent de submerger la recherche contre le cancer

26.02.2026 15:02 👍 1 🔁 1 💬 0 📌 2

Scientific paper mill: the model flagged 10% of the research papers in cancer research as problematic 😱

www.bmj.com/content/392/...

26.02.2026 20:00 👍 0 🔁 0 💬 0 📌 0
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It’s finally out! Together with @embopress.org and
@reviewcommons.org, we conducted a structured side-by-side comparison of human peer review and our AI scientific review (see thread 👇👇👇🔥).

26.02.2026 14:34 👍 77 🔁 38 💬 2 📌 4
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10°C temperature anomalies...

26.02.2026 19:23 👍 79 🔁 9 💬 5 📌 0
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Nuclear speckles enable processing of RNA from GC-rich isochores Nuclear speckles are key subnuclear structures that regulate gene expression in GC-rich regions. This work shows that the evolution and expansion of core speckle proteins were crucial for the increase...

The function of nuclear speckles is revealed! This is an incredibly important paper with absolutely beautiful data! Wow! www.cell.com/cell/fulltex...

25.02.2026 17:43 👍 37 🔁 15 💬 1 📌 1
ShineGAL4 FLP-out clones

ShineGAL4 FLP-out clones

#Drosophila calling. Delighted to share our new collection of ShineGAL4 drivers for CNS, FB, muscles, enterocytes, oenocytes and MTs made by @vgirard.bsky.social, @sebsorge.bsky.social and colleagues @crick.ac.uk. All at Bloomington @bdsc.bsky.social

@dev-journal.bsky.social
tinyurl.com/4jpw9jd6

25.02.2026 16:03 👍 43 🔁 23 💬 1 📌 2
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Post-replicative chromatin accessibility predicts cell fate change Knudsen and colleagues use repli-ATAC-seq to compare replicated and unreplicated chromatin in two models of cell identity change. They find that lineage-specific elements are accessible earlier in rep...

DNA replication globally disrupts the epigenome. But does this create a chromatin-access opportunity for TF binding to facilitate cell identity change? Now 𝐫𝐞𝐩𝐥𝐢-𝐀𝐓𝐀𝐂-𝐬𝐞𝐪 shows 𝘥𝘦 𝘯𝘰𝘷𝘰 chromatin opening & TF binding occurs specifically post-replication, in cellular differentiation & reprogramming!

25.02.2026 18:50 👍 67 🔁 26 💬 1 📌 0
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Join us for a day of talks, posters, and discussions, featuring a morning joint lecture with Nobel Laureates Eric F. Wieschaus and Christiane Nüsslein-Volhard!
Date: Monday, May 4th, 2026
Location: University of Copenhagen, Mærsk Tower
sites.google.com/view/emergin...
Free to participate

24.02.2026 07:57 👍 23 🔁 20 💬 1 📌 0
An advertisement for a PhD position studying "Revealing the mechanistic basis of defence peptide antibacterial specificity." It shows fruit flies infected by green-fluorescent protein expressing bacteria, and describes the project and way to apply.

An advertisement for a PhD position studying "Revealing the mechanistic basis of defence peptide antibacterial specificity." It shows fruit flies infected by green-fluorescent protein expressing bacteria, and describes the project and way to apply.

Very excited to be advertising this project with the excellent cosupervision of Peter Mergaert through @i2bcparissaclay.bsky.social and @uniexecec.bsky.social.

This position is open to international applicants and will involve stints in both Penryn UK and Paris France. Please share!

Apply: adum.fr

23.02.2026 21:23 👍 17 🔁 25 💬 1 📌 0
Non c’est Non, Monsieur Duplomb ! - Non c’est Non, Monsieur Duplomb ! - Plateforme des pétitions de l’Assemblée nationale Pourquoi cette pétition est cruciale Le Sénateur Laurent Duplomb propose (une nouvelle fois) la réintroduction de l’acétamipride, un insecticide de la famille des néonicotinoïdes. Sous couvert d’urgen...

Environ 336000 signataires pour la pétition contre Duplomb 2 : c'est trop peu ; et il s'agit vraiment de se réveiller pour empêcher cette mesure de destruction de notre santé (n'hésitez pas à republier ce post ou à alerter vos propres abonnés) :

petitions.assemblee-nationale.fr/initiatives/...

22.02.2026 18:10 👍 347 🔁 620 💬 12 📌 31
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The political effects of X’s feed algorithm - Nature Among users initially on a chronological feed, 7 weeks of exposure to X’s algorithmic feed in 2023 shifted political attitudes and account-following behaviour in a more conservative direction compared...

Brainwashing, 2026 edition. This paper shows how X's algorithmic feed shifts people's views rightwards. It's a sophisticated, highly effective form of reorientation. And it is utterly chilling.
If you're still on that platform, unhook yourself now.
www.nature.com/articles/s41...

23.02.2026 07:42 👍 2605 🔁 1573 💬 82 📌 136
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Impaired stem cell migration and divisions in Duchenne muscular dystrophy revealed by live imaging - Nature Communications Using live-imaging in vivo and ex vivo, Sarde et al. show that dystrophic muscle stem cells have precocious differentiation through symmetric divisions and impaired migration, with differential impact...

Bravo Liza, Brendan and colleagues for the elegant work on multiple live imaging strategies to untangle mechanisms of muscular dystrophy! www.nature.com/articles/s41...

21.02.2026 13:05 👍 19 🔁 11 💬 1 📌 1

Group Leader Call at the @cbitoulouse.bsky.social in
Genome biology, projects at the interface with devbio will be given particular attention. please share :)
cbi-toulouse.fr/wp-content/u...

17.02.2026 16:05 👍 28 🔁 31 💬 1 📌 0
Graphic showing changes in CO₂, global temperatures and global sea levels over the last 2025 years. Steep increases are visible after the industrial revolution.

Graphic showing changes in CO₂, global temperatures and global sea levels over the last 2025 years. Steep increases are visible after the industrial revolution.

Updated climate indicators graphics, now including 2025

ed-hawkins.github.io/climate-visu...

13.02.2026 11:33 👍 385 🔁 256 💬 11 📌 28
New registration New registration

The registration is open! Junior #Drosophila PIs, join us for inspiring scientific discussion, contribute a talk and listen to our keynote speaker, Eugenia Chiappe. We meet in Palmela, Portugal from June 1st to 3rd. Register soon as spots are limited!

congressos.mundiconvenius.pt/geral/inseri...

20.02.2026 15:04 👍 18 🔁 14 💬 0 📌 3

Happy to share scHiCAR, an ultra-high throughout (millions of cells), low cost (5 cents/cell including NGS), and trimodal platform for integrated single-cell level analysis of mRNA, open chromatin, and 5-kb resolution looping with ground-truth data the same individual cell.

20.02.2026 02:51 👍 77 🔁 33 💬 0 📌 6
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🔬 Recruiting a Postdoc!!!!
I’m looking for a motivated postdoc to join my lab and work on characterizing the role of a heterochromatin protein involved in a sex-ratio meiotic drive system in Drosophila.
If you know someone who might be interested, please share widely!

19.02.2026 17:21 👍 14 🔁 15 💬 0 📌 1

This will feature an #EPIC scientific program. Something you have not seen before. Trust me 😉 CBG Alumni of all nations, unite!

18.02.2026 16:23 👍 15 🔁 5 💬 1 📌 1
FlyBase:Contribute to FlyBase - FlyBase Wiki

Dear UK #Drosophila @FlyBase Cambridge is now able to accept PO orders for support. So please get in touch with
https://wiki.flybase.org/wiki/FlyBase:Contribute_to_FlyBase

17.02.2026 21:18 👍 10 🔁 12 💬 1 📌 0

Un poste de Professeur des Universités va être ouvert lors de la campagne d’emploi 2026 à l’université Claude Bernard Lyon1 -
Profil Recherche : Biologie Moléculaire des Eucaryotes.
Profil Enseignement: Biologie Moléculaire.
Profil ci-joint.
Merci de diffuser dans vos réseaux.

17.02.2026 08:04 👍 14 🔁 20 💬 1 📌 0
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Expertise Before Augmentation: A developmental framework for sequencing AI use in PhD training doi.org/10.59350/ja1...

17.02.2026 17:30 👍 5 🔁 1 💬 0 📌 0
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Spineless, Gutless RepubliKKKans.

17.02.2026 10:19 👍 42 🔁 25 💬 3 📌 4