Martina Parigi

Shaping epithelial tissues by stem cell mechanics in development and cancer - Nature Reviews Molecular Cell Biology Adult stem cells self-renew and differentiate to build, maintain and repair tissues. This Review discusses recent insights into the contribution of mechanical forces produced by epithelial stem cell a...

Very happy to see our review out in @natrevmcb.bsky.social!
Here we discuss how stem cells exert forces to sculpt tissues in development and homeostasis, and how stem cell mechanics go awry upon malignant transformation. Read it here 👇
www.nature.com/articles/s41...

and a big thank you to Eduardo Villablanca for his invaluable mentorship during my PhD!

Thanks to my co-authors Srustidhar Das and Xinxin Luo that made this journey so much fun!

Very excited to share our latest work on the uncoupling of epithelial regeneration and tumorigenesis in the gut! nature.com/articles/s41...