Rachel Buckley, PhD's Avatar

Rachel Buckley, PhD

@bucklr01

Assoc Prof [Harvard Med School/MGH] - researching sex differences and women's brain health in Alzheimer's disease - twin mum - Aussie + advocate for women in STEM Chair of Sex and Gender AD PIA for #ISTAART

1,361
Followers
561
Following
55
Posts
16.11.2024
Joined
Posts Following

Latest posts by Rachel Buckley, PhD @bucklr01

Preview
Brains, biases and amyloid beta: Why the female brain deserves a closer look in Alzheimer’s research New results suggest the disease progresses differently in women, but we need more basic science to unpack the mechanisms involved.

Congratulations to Rachel Buckley @bucklr01.bsky.social on being a finalist for a National Association of Science Writers @sciencewriters.org award. Read Rachel's essay,
www.thetransmitter.org/sex-differen...

#neuroskyence

30.09.2025 21:36 πŸ‘ 37 πŸ” 13 πŸ’¬ 0 πŸ“Œ 0
Preview
Announcing the 2025 NASW Science in Society Journalism Award winners The National Association of Science Writers and its Awards Committee are pleased to announce the winners of the **2025 NASW Science in Society Journalism Awards.** This year, NASW is awarding prizes i...

Congrats to @bucklr01.bsky.social on being selected as a finalist in the NASW Science in Society Journalism Awards, for her piece "Brains, biases and amyloid beta: Why the female brain deserves a closer look in Alzheimer’s research"! www.nasw.org/article/anno...

01.10.2025 02:08 πŸ‘ 7 πŸ” 5 πŸ’¬ 1 πŸ“Œ 0
Preview
Unlocking Sex-Based Differences in Alzheimer’s Risk with Dr. Rachel Buckley Research Renaissance: Exploring the Future of Brain Science Β· Episode

I was fortunate enough to be interviewed by the Karen Toffler Charitable Trust on their Research Renaissance podcast! I talk about sex differences in Alzheimer's disease risk and optimizing women's brain health.

A link for those interested: open.spotify.com/episode/3ou4...

16.07.2025 16:25 πŸ‘ 12 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0

Final date to get your votes in!!

25.06.2025 19:35 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Don't forget to vote!!! June 25 is the due date. @drjessicacaldwell.bsky.social @shabanashaik.bsky.social @judy-pa.bsky.social

19.06.2025 00:29 πŸ‘ 7 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1

Our new paper is out!

We find that Sex Hormone Binding Globulin (but interestingly not estradiol or testosterone) shows sex specific associations with tau-PET burden in the Framingham Heart Study. In men, it seems to be protective (higher SHBG = lower tau)

onlinelibrary.wiley.com/doi/10.1002/...

17.06.2025 19:52 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
2025 PIA Executive Committee Elections 2025 PIA Executive Committee Elections

Hey y'all - please vote for your new Sex & Gender Professional Interest Area for the Alzheimer's Association ISTAART!!!!

Voting closes JUNE 25!!!

alz.surveymonkey.com/r/T8GC8J6

13.06.2025 15:27 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1
Post image

Biomarkers enhance Cerebral Amyloid Angiopathy detection!🩸

Research from Alzheimer’s & Dementia demonstrate lower AΞ²42/40 and elevated p-tau-181 effectively differentiate CAA from controls, opening doors for non-invasive diagnostics #AlzResearch

alz-journals.onlinelibrary.wiley.com/doi/full/10....

09.04.2025 15:29 πŸ‘ 6 πŸ” 2 πŸ’¬ 0 πŸ“Œ 1
Post image

AI used for better dementia detection in India

A&D: Diagnosis, Assessment & Disease Monitoring reports cognitive test cutoffs for India’s unique population to improve early diagnosis, a step toward more effective dementia care #DADM #AlzResearch

alz-journals.onlinelibrary.wiley.com/doi/full/10....

10.04.2025 14:33 πŸ‘ 6 πŸ” 5 πŸ’¬ 0 πŸ“Œ 1

Loved being at #CCAD2025 this year in Puerto Rico - been an amazing conference!

10.04.2025 13:47 πŸ‘ 6 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
SPECIAL SECTION: Modifiable Risk Factors In Dementia. Edited By Dr. Kaarin Anstey & Dr. Kristine Yaffe: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring Click on the title to browse this issue

What are examples of modifiable risk factors in dementia?

A&D: Diagnosis, Assessment & Disease Monitoring special issue investigates glucose index, sleep variation, vitamin supplements and more as modifiable risk factors #DADM

Read here: alz-journals.onlinelibrary.wiley.com/doi/toc/10.1...

01.04.2025 19:25 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 1
Preview
Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease - Nature Medicine Plasma eMTBR-tau243 is a specific biomarker of tau tangles in Alzheimer’s disease and enables the detecting and tracking of Alzheimer’s clinical impairment.

We now have a blood biomarker that is even more strongly associated with tau PET and cognitive symptoms than even p-tau217! Plasma eMTBR-tau243 will help us to understand whether cognitive impairment is likely to be related to Alzheimer's pathology. #ENDALZ

www.nature.com/articles/s41...

31.03.2025 14:56 πŸ‘ 47 πŸ” 12 πŸ’¬ 0 πŸ“Œ 1

A critical area of AD research that is really gaining traction - harmonization across multiple cohorts for big data analysis!

31.03.2025 15:23 πŸ‘ 6 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
The Fredericks Lab! - with deliberately poor photoshopping of lab members who couldn't be there that day.

The Fredericks Lab! - with deliberately poor photoshopping of lab members who couldn't be there that day.

We are HIRING!! Postdoc for multimodal imaging lab at Yale. If you get excited about preclinical and prodromal states, atypical Alzheimer’s, graph theory, predictive modeling, and/or baked goods at lab meetings, come join us: postdocs.yale.edu/postdoctoral...

Please share with your circles!

28.03.2025 17:26 πŸ‘ 8 πŸ” 11 πŸ’¬ 1 πŸ“Œ 0

WOW - congrats!!!!!!!

20.03.2025 11:33 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
Post image
10.03.2025 18:05 πŸ‘ 9 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
Preview
Alzheimer's May Develop Differently in Women Women show faster tau accumulation than men

"Women have faster rates of tau accumulation than men in areas of the brain that tend to be most vulnerable to Alzheimer's disease." -- @bucklr01.bsky.social, of Massachusetts General Hospital, discussing women and #Alzheimer'sDisease.
www.medpagetoday.com/neurology/al...

10.03.2025 13:51 πŸ‘ 2 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

It is an honor to be counted amongst these amazing scientists in this piece, and a privilege to be able to do this incredible work

07.03.2025 20:09 πŸ‘ 5 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
Preview
Aging Women’s Brain Mysteries Are Tested in Trio of Studies Researchers identified a gene that seems to help slow brain aging in women, and studied links between hormone therapy, menopause and Alzheimer’s.

Great write up on the latest research on sex differences in brain aging, with quote from Dr. Buckley @bucklr01.bsky.social "talk to your doctor" πŸ˜‰ Important work--particularly in the context of clamping down on science focused on the health of women and minorities www.nytimes.com/2025/03/05/h...

05.03.2025 20:38 πŸ‘ 17 πŸ” 5 πŸ’¬ 1 πŸ“Œ 0

Thanks to @denadubal.bsky.social and @bucklr01.bsky.social for talking to me for this story about the fascinating X chromosome!

05.03.2025 20:57 πŸ‘ 6 πŸ” 3 πŸ’¬ 3 πŸ“Œ 0

@sheilashanmugan.bsky.social @magdamartinezga.bsky.social @susanacarmona.bsky.social @bucklr01.bsky.social, @denadubal.bsky.social Laura Pritschet, Kaitlin Casaletto, Ina Stelzer, Julia Sacher, Rob Froemke and so many more leading minds.

05.03.2025 21:34 πŸ‘ 5 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Preview
Aging Women’s Brain Mysteries Are Tested in Trio of Studies Researchers identified a gene that seems to help slow brain aging in women, and studied links between hormone therapy, menopause and Alzheimer’s.

More coverage of @denadubal.bsky.social Kaitlin Casaletto, @bucklr01.bsky.social et al: www.nytimes.com/2025/03/05/h...

06.03.2025 01:54 πŸ‘ 7 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
Preview
2025 ISTAART PIA Executive Committee Self-Nominations Take this survey powered by surveymonkey.com. Create your own surveys for free.

Nominations are still open to become a part of our Sex & Gender PIA Executive Committee for ISTAART!!! Nominations close Mar 10. Please see nomination form: alz.surveymonkey.com/r/RF7JGFF
Information on the positions are here: drive.google.com/file/d/1NKvx...
For any questions, DM me #endAlz

04.03.2025 14:51 πŸ‘ 5 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
Post image

UPDATE ON FUNDING

These are data through 2/21/25. The lag in Reporter really does appear to be about a week.

There was a second mini-pause as suspected from internal reports, but grants are being awarded.

About 21% new or competitive renewals (compared to 29% in 2017, and 22% in 2021

27.02.2025 10:14 πŸ‘ 106 πŸ” 46 πŸ’¬ 4 πŸ“Œ 4

If interested to be considered for future reviewing opportunities, please reply here. I'm trying to ascertain the amount of interest to determine paths forward for finding new manuscript reviewers. Thank you!

27.02.2025 02:26 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Hey there, fellow scientists! Interested in reviewing for an Alzheimer's disease journal in future? Us editors are always looking for reviewers, especially those who are earlier career researchers who are looking to test out their reviewing chops.

27.02.2025 02:26 πŸ‘ 6 πŸ” 2 πŸ’¬ 3 πŸ“Œ 0
Preview
2025 ISTAART PIA Executive Committee Self-Nominations Take this survey powered by surveymonkey.com. Create your own surveys for free.

Please consider nominating to join our Sex & Gender PIA Executive Committee for ISTAART!!! We'd love to have you join our amazing team #ADSexGenPIA

alz.surveymonkey.com/r/RF7JGFF

21.02.2025 14:02 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
How a Canadian scientist and a venomous lizard helped pave the way for Ozempic - National | Globalnews.ca In 1984, Dr. Daniel Drucker, an endocrinologist from the University of Toronto, discovered a hormone that helped pave the way for popular diabetes drugs such as Ozempic.

Whenever you hear someone sneer about scientific research that seems useless to them β€” β€œthey’re studying the spit of lizards?!” β€” remind them that’s exactly how we got Ozempic.

globalnews.ca/news/9793403...

09.02.2025 17:38 πŸ‘ 30118 πŸ” 7862 πŸ’¬ 514 πŸ“Œ 267
Preview
Opinion | The Devastating Legacy of Lies in Alzheimer’s Science Fraud in research needs to end.

My first science post here on BlueSky is a long one. Setting the contrarian tone from the very beginning, I take strong issue with the recent op-ed by Charles Piller published in the January 24th NY Times on #Alzheimer's disease (nam12.safelinks.protection.outlook.com?url=https%3A...)

30.01.2025 21:38 πŸ‘ 53 πŸ” 23 πŸ’¬ 4 πŸ“Œ 13

I can confirm this is a great crew...join us!!

10.01.2025 15:54 πŸ‘ 3 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0