Katharina Lichter

Congrats - great contribution!

Electron microscopy is @nature.com's Method of the Year! 🧠🔬🏆

@natmethods.nature.com shares why MICrONS and FlyWire are proof that #ElectronMicroscopy is helping us see the brain and its incredible complexity at a new level: https://www.nature.com/articles/s41592-025-02988-6

🧠📈 #studyBRAIN

Kiss, shrink, run A unified mechanism directs synaptic vesicle release

Kiss, shrink, run | Science www.science.org/doi/10.1126/...

Not clear yet. The authors demonstrate this for glutamatergic synapses in dissociated hippocampal neuron cultures.

“Kiss-shrink-run” unifies mechanisms for synaptic vesicle exocytosis and hyperfast recycling Synaptic vesicle (SV) exocytosis underpins neuronal communication, yet its nanoscale dynamics remain poorly understood owing to limitations in visualizing rapid events in situ. Here, we used optogenet...

Original paper: doi.org/10.1126/scie...

Kiss, shrink, run A unified mechanism directs synaptic vesicle release

Kiss, Shrink, Run ⛹🏻‍♀️ New Perspective in @science.org about one of my favourite topics: how synapses and their tiny vesicles communicate in the brain. Chang-Lu Tao and colleagues reveal a previously unknown pathway for vesicle release. Read more here: doi.org/10.1126/scie... @istaresearch.bsky.social

Congratulations!

Congratulations!

Thanks for the great opportunity to participate @istaustria-iof.bsky.social 🍩🧠💡

We are delighted and very satisfied with a extremely smooth installation of the @abberior.rocks Mirava Polyscope, by 2 fantastic engineers. Our new ‘imaging soldier’ is equipped with 2- and 3D STED, MINDLUX, adaptive optics, lifetime imaging, matrix detectors and options for spectral imaging.

Doing a post doc

Congrats 🚀

The @erc.europa.eu awards Advanced Grants to “active researchers who have a track-record of significant research achievements.” ISTA could now secure a quadruple success in the most recent call for these prestigious European grants. #ERCAdG

Memory by a thousand rules: Automated discovery of functional multi-type plasticity rules reveals variety & degeneracy at the heart of learning Synaptic plasticity is the basis of learning and memory, but the link between synaptic changes and neural function remains elusive. Here, we used automated search algorithms to obtain thousands of str...

We just pushed “Memory by a 1000 rules” onto bioRxiv, where we use clever #ML to find #plasticity quadruplets (EE, EI, IE, II) that learn basic stability in spiking nets. Why is it cool? We find 1000s!! of solutions, and they don’t just stabilise. They #memorise! www.biorxiv.org/content/10.1...

How radial glia progenitor lineages generate cell-type diversity in the developing cerebral cortex The cerebral cortex is arguably the most complex organ in humans. The cortical architecture is characterized by a remarkable diversity of neuronal and…

Curious about the latest news on how RGP lineages generate cortical neuronal diversity? Don't miss our new review from @HippenmeyerLab written by @fabripipicelli.bsky.social and myself www.sciencedirect.com/science/arti...

Congrats 🤩

How radial glia progenitor lineages generate cell-type diversity in the developing cerebral cortex The cerebral cortex is arguably the most complex organ in humans. The cortical architecture is characterized by a remarkable diversity of neuronal and…

www.sciencedirect.com/science/arti...
Our new review in Current Opinion in Neurobiology is out! "How radial glia progenitor lineages generate cell-type diversity in the developing cerebral cortex"

@chaichinta.bsky.social impressive results!!! 🤩

Enjoy and best from Vienna :)

Hi Sam, very interesting thoughts. If you would look further downstream, e.g. towards the presynaptic active zones and the direct release of vesicles in synaptic terminals, we know that these active zone protein composition might be specific for some synapses, even within one organism.

Hi Tanja, thanks for sharing your insights! Sorry that you had such an experience. Katharina

Sehr informativ! Well done!

Hi Antje, cool work! On my reading list :) congrats!

Great!

Congrats, super cool work!

🔬 Ever wondered how therapeutic antibodies work?
3D LLS-TDI-DNA-PAINT and live-cell LLS microscopy allow decoding of the molecular interplay of endogenous CD20 on B cells with therapeutic antibodies.

📄 Read more: www.science.org/doi/10.1126/...

I really appreciate @neuroandbeyond.bsky.social - great topics, always a pleasure to listen!

New brain aging study is out today in Nature

The largest single-cell RNA seq dataset of mouse brain aging reveals incredible insights and could pave the way for future therapies to slow or manage the impacts of the aging process. 🧵 #studyBRAIN

Human cortical pyramidal neurons are larger, with more elaborate branching, and distinct nonlinear biophysical properties compared to rat cortical pyramidal neurons.

Are they more functionally complex? Could that boost the human brain’s computational power? and is that what makes us human? (1/11)

A group of longhorn crazy ants (top) and a group of people (bottom) tackling scaled versions of the same geometrical maneuvering puzzle. CREDIT: Ofer Feinerman

Researchers challenged longhorn crazy ants and humans with the same task: maneuvering a T-shaped object through two consecutive open doorways. Single humans always outperformed single ants, but ant groups could beat human groups. In PNAS: www.pnas.org/doi/10.1073/...