Shiladitya Banerjee

Can biological tissues "learn"? Our new preprint shows that epithelial tissues exhibit emergent behaviors akin to unsupervised learning. Local tension remodeling allows cell networks to store long-range memory and program global elasticity properties.

Read more here: www.biorxiv.org/content/10.6...

Reinforcement learning for adaptive control of phenotypically heterogeneous bacterial populations Bacterial populations display extraordinary resilience to antibiotic stress, driven by diverse physiological states that allow some cells to persist and later repopulate. This phenotypic heterogeneity...

www.biorxiv.org/content/10.1...

Physical traits of supercompetitors in cell competition | Journal of The Royal Society Interface Cell competition is a fitness control mechanism in tissues, where less fit cells are eliminated to maintain tissue homeostasis. Two primary mechanisms of cell competition have been identified: contact...

royalsocietypublishing.org/doi/10.1098/...

Cell Geometry Limits Bacterial Metabolic Efficiency Bacterial metabolic strategies are fundamentally linked to their physical form, yet a quantitative understanding of how cell size and shape constrain the efficiency of biomass production remains poorl...

Cell Geometry Limits Metabolic Efficiency
www.biorxiv.org/content/10.1...

Design principles and feedback mechanisms in organelle size control Intracellular organelles are essential for cellular architecture and function, and their size regulation is critical for maintaining cellular homeosta…

Check out our new opinion/review on Organelle Size Control
www.sciencedirect.com/science/arti...

That's excellent!

Power-law memory governs bacterial adaptation and learning in fluctuating environments How do single-celled organisms adapt and learn to survive in dynamic environments without a nervous system? Here, we provide experimental evidence and a theoretical model demonstrating learning-like b...

Excited to share our new preprint on bacterial learning, with @sifangwei.bsky.social. Here we show that single bacterial cells can continually learn in dynamic environments, due to an underlying reaction network architecture that resemble a recurrent neural network
www.biorxiv.org/content/10.1...

good journal. Congrats!

Congrats Jake

PoLS faculty Dan Goldman has been named a lifetime fellow of the American Association for the Advancement of #Science (@aaas.org)!

Congratulations to Dan, and also to the six other @gtresearchnews.bsky.social honorees named this year!

Read about our latest work on centrosome size control, Version of Record now available @elife.bsky.social

Big shout out to Jian Liu, @shilabanerjee.bsky.social and @simonereber.bsky.social for organizing a great subgroup meeting on Physical Cell Biology at #BPS2025 at Los Angeles. And afterwards a very enjoyable lunch for the speakers😁

Beautiful work. Congrats!

AAMC Lawsuit Results in Nationwide Temporary Restraining Order on Proposed Drastic Cuts to NIH Funding Judge grants restraining order after lawsuit led by the AAMC, challenging the legality of the administration’s plan to make cuts to federally funded research.

www.aamc.org/news/press-r...

Detecting subtle subterranean movement via laser speckle imaging Summary: Laser speckle imaging non-invasively quantifies subterranean organism activity by detecting nanometer-scale movements.

How can subterranean organisms be observed as they move underground? A recent paper from Dan Goldman's CRAB Lab presents Laser Speckle Imaging (LSI) as a non-invasive way to view organisms as they move through granular media. #Physics #Biology doi.org/10.1242/jeb....

Hi Folks, the Physical Cell Biology subgroup of the BPS is currently searching for a secretary treasurer. We are seeking two nominations to run for an election. DM me if interested. Pleaee
Repost.

A betrayal to those who opted for the new framework. Why not simply accept/reject then?

Cell-scale biophysical determinants of cell competition in epithelia Mechanical competition is controlled by biophysical parameters that regulate cellular homeostatic density, while biochemical competition is regulated by parameters that influence the organisation of c...

Please cite doi.org/10.7554/eLif...
as you are using a movie from this paper without crediting

Hindbrain neuropore tissue geometry determines asymmetric cell-mediated closure dynamics in mouse embryos | PNAS Gap closure is a common morphogenetic process. In mammals, failure to close the embryonic hindbrain neuropore (HNP) gap causes fatal anencephaly. W...

Work led by postdoc Fernanda Perez-Verdugo, with a very productive collaboration with Gabriel Galea's lab @UCL and @emaniou.bsky.social. Many thanks to Gabe for introducing me to this intriguing model system.

Read our earlier work on hindbrain neuropore closure here: www.pnas.org/doi/abs/10.1...

How do physical forces influence spatiotemporal cell patterning during tissue morphogenesis? Our latest preprint integrates theoretical modeling with live imaging of mouse embryos to reveal how mechanosensitive feedback drives self-organized cell patterning during hindbrain neuropore morphogenesis.

How about 'Blueps'

🎉 Excited to share the news that my group will soon be moving to Georgia Tech to begin a new chapter in the Physics of Living Systems. Grateful for an incredible 5 years at CMU. We’re hiring postdocs - join us!

Couldn't find one so made a quick physics of life list, enjoy! go.bsky.app/EA2VsDN