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Sarah Ashley

@sarah-ashley

Computational biologist @MCRI | Naarm Melbourne Center for Food Allergy Research | National Allergy Centre of Excellence | #WomenInSTEM πŸ§‘πŸ»β€πŸ”¬ Postdoctoral fellow working on treatments for food allergies πŸ₯œ #scRNAseq #systemsbiology #VIIN Emerging Leaders ELC

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14.11.2024
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Latest posts by Sarah Ashley @sarah-ashley

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πŸ“’Are you a postdoctoral researcher with an excellent track record in #immunology and/or related field? We are hiring, but hurry, call closes 27 November! Apply and join us in Finland! Read more πŸ‘‰ https://bit.ly/4r83ktP
#ImmunoSky #MedSky #LifeScience

21.11.2025 08:48 πŸ‘ 5 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0

Had an absolute blast attending my first #VIINYIS! Such a great day of exciting science hearing from our young investigators in the VIIN community. Thanks for a fab conference #youngVIIN2025
Until next time!

14.11.2025 11:01 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Inspiring Keynote from Nancy Wang Ruth Bishop Fellow and new Team Leader at MCRI. She took us through her research harnessing CD4T cell-mediated immunity against Salmonella working to develop candidate protein vaccines and on immune-based assays for enteric fever surveillance
#YoungVIIN2025 #VIINYIS

14.11.2025 04:45 πŸ‘ 4 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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Fantastic talk "A high-dimensional flow cytometry profiling on peripheral blood mononuclear cells of transitioning transgender individuals" by Den Celesta from @mcri.bsky.social @unimelb.bsky.social
#YoungVIIN2025 #VIINYIS

14.11.2025 05:32 πŸ‘ 4 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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Our first Keynote speaker group leader Marcel Doerflinger from @wehi-research.bsky.social giving an overview of his career trajectory to becoming a lab head, including 6 key tips on how to succeed #YoungVIIN2025 #VIINYIS

13.11.2025 23:09 πŸ‘ 5 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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An excellent talk from @therealmonocyte.bsky.social from MCRI about the Determinants of innate immune cytokine responses in pre-school children!
#YoungVIIN2025 #VIINYIS

13.11.2025 22:38 πŸ‘ 7 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

Here bright and early for #YoungVIIN2025 #VIINYIS πŸ§ͺ🧫🧬

13.11.2025 21:39 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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By popular demand, oral abstract submissions for Lorne Infection and Immunity 2026 have been extended to Friday 17th October!

Join our exciting 2026 program alongside a fantastic line-up of International and National Invited Speakers.

⏰Only three days left, so don't miss out!

13.10.2025 23:58 πŸ‘ 3 πŸ” 4 πŸ’¬ 1 πŸ“Œ 1

I am looking forward to attending Lorne I&I next year. To my friends and colleagues overseas, this is the excuse you were looking for to come visit Australia!!!! 🦘🐨🧫🧬πŸ§ͺ🦠

08.10.2025 10:28 πŸ‘ 6 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

PSA, deadline for the 16th Annual Lorne Infection & Immunity Conference this Friday!πŸƒβ€β™‚οΈπŸ’¨
Don't miss your chance to submit an oral abstract and apply for a Career Development Award

08.10.2025 09:25 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Join us for our annual VIIN Young Investigator Symposium!

πŸ—“οΈ Fri 14th Nov 8:00am-7:30pm
πŸ“Monash Institute of Pharmaceutical Sciences, Parkville

Abstract submissions close next Fri 29th Aug!

Register now! πŸ‘‡
bit.ly/471WFK0
#VIINYIS

22.08.2025 08:24 πŸ‘ 6 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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πŸ“ Working on a manuscript? Not sure on how to navigate the submission process?

Join our next workshop β€œManuscript Mastery” for all the tips and tricks on how to prepare your work for publication!

πŸ•°οΈ Wed 10th Sept 10am - 12pm

Register by 5pm Friday 5th September
bit.ly/45gWCst

14.08.2025 05:56 πŸ‘ 6 πŸ” 4 πŸ’¬ 0 πŸ“Œ 1
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Thor: a platform for cell-level investigation of spatial transcriptomics and histology - Nature Communications Zhang, Chen, and colleagues present Thor, a platform that turns spot-level spatial transcriptomics into single-cell gene maps using the paired histology image, without using single-cell RNA-seq data.…

Thor: a platform for cell-level investigation of spatial transcriptomics and histology. #SpatialTranscriptomics @natcomms.nature.com
www.nature.com/articles/s41...

13.08.2025 11:15 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Announcing taxburst, an update of the Krona software for taxonomy exploration Announcing taxburst for metagenome taxonomy!

taxburst v0.3.0 is now released - this is an update of the Krona visualization system for microbiome/metagenome taxonomy analyses. Enjoy!

08.08.2025 14:19 πŸ‘ 26 πŸ” 17 πŸ’¬ 0 πŸ“Œ 0
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What is the mechanism of food-induced anaphylaxis?
Today @science.org unravelled
www.science.org/doi/full/10....
Gut mast cell leukotriene release
@rmedzhitov.bsky.social

07.08.2025 20:06 πŸ‘ 86 πŸ” 27 πŸ’¬ 3 πŸ“Œ 0
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Cysteinyl leukotrienes stimulate gut absorption of food allergens to promote anaphylaxis in mice Food-specific immunoglobulin E (IgE) triggers life-threatening anaphylaxis; however, for unclear reasons, some people with food-specific IgE are asymptomatic upon allergen consumption. We studied stra...

Thoroughly #enjoyed #reading this #paper. #Genetics here is amazing. Cysteinyl leukotrienes stimulate gut absorption of food allergens to promote anaphylaxis in mice | Science www.science.org/doi/10.1126/...

08.08.2025 14:59 πŸ‘ 5 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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"Current patterns of plastic production, use, and disposal cause disease, disability, and death at every stage of the plastic lifecycle." @thelancet.com
www.thelancet.com/journals/lan...

04.08.2025 14:07 πŸ‘ 141 πŸ” 66 πŸ’¬ 4 πŸ“Œ 3
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One in 4 people carry one copy of the APOE4 allele, the strongest known genetic risk factor for Alzheimer's disease. We've just learned how that risk is mediatedβ€”the immune system
erictopol.substack.com/p/our-braini...

04.08.2025 21:09 πŸ‘ 268 πŸ” 86 πŸ’¬ 5 πŸ“Œ 2

The future of multi-omics?
πŸ” A supervised deep neural network trained on longitudinal multi-omic data (BioMapAI) enabled identification of disease and symptom specific biomarkers in ME/CFS and construction of a connectivity map of the microbiome, immune system and plasma metabolome

30.07.2025 23:29 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Predicting the translation efficiency of messenger RNA in mammalian cells. #TranslationEfficiency #TranslationalControl @natbiotech.nature.com
www.nature.com/articles/s41...

29.07.2025 09:15 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Combined single-cell profiling of chromatin–transcriptome and splicing across brain cell types, regions and disease state. #SingleCellProfiling #RNAsplicing #Chromatin #Transcriptome @natbiotech.nature.com 🧬
www.nature.com/articles/s41...

29.07.2025 10:30 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Great to hear about Dr Halina Pietrzak’s work as a clinical trials coordinator. Highlighting the direct impact she sees on patients through their work, and how important communication and problem solving are for her position!

#VIINcareers

30.07.2025 21:18 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Thanks to Dr Andrew Foers to showing us what it takes to go from PhD to patent scientist! Andrew shared valuable perspectives on how skills from PhD and post-doc can transfer over to patents but also key differences!

#VIINcareers

30.07.2025 21:16 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Thanks to Dr Rebecca Smith for starting off our Careers Evening! Giving us insight in her journey from research to development. As Rebecca put it "Be brave, take a few risks, be kind to yourself. Things will evolve as they need to."
#VIINcareers

30.07.2025 21:14 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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A great talk from Dr Jodie Abramovitch accompanied by excellent art and insights into the role of a principal scientist at a contract research organisation. Thanks for reminding us all of to trust ourselves and our guts!

#VIINcareers

30.07.2025 11:05 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Fantastic insights from Dr Nicholas Liau on challenging yourself, doing things outside of your comfort zone and living beyond the now-- make time to think about your future. Diversifying your experiences can seem intimidating but can lead to great things. #VIINcareers

30.07.2025 09:30 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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CORNETO: machine learning to decode complex omics data New tool combines biological knowledge with machine learning to help researchers extract meaningful insights from complex omics data.

How can we find out what’s really going on inside cells when we’re generating so much complex data?

CORNETO is an open-source tool that uses machine learning to turn tangled omics datasets into clear maps of how genes, proteins, and signalling pathways interact.

www.ebi.ac.uk/about/news/r... πŸ§ͺ

22.07.2025 09:20 πŸ‘ 38 πŸ” 10 πŸ’¬ 1 πŸ“Œ 0
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We can predict a person's risk of coronary artery disease better than ever before. Cover of new
@naturemedicine.bsky.social
regarding our @scripps.edu recent paper
nature.com/articles/s41...

23.07.2025 14:01 πŸ‘ 77 πŸ” 22 πŸ’¬ 5 πŸ“Œ 1

πŸ“ So happy to share that the multi-omic mechanisms of peanut OIT πŸ₯œ study I worked on during my postdoc in Berlin is now published and open access. I am excited to share these new findings❗️

23.07.2025 00:38 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Don't miss your opportunity to attend @theviin.bsky.social Careers Evening.
Deadline extended to COB today❗️ So get in quick πŸƒβ€β™€οΈπŸ’¨

21.07.2025 02:44 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0