ChloΓ© Roffay's Avatar

ChloΓ© Roffay

@chloeroffay

From physics to cells to gastruloids β€’ Postdoc in @dianapinheiro.bsky.social β€’ PhD : @rouxlab.bsky.social πŸ”¬πŸ¬ 🎨 β€’ alum cpes @psl-univ.bsky.social β€’ she/her β€’ Views my own

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03.09.2024
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Latest posts by ChloΓ© Roffay @chloeroffay

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First 24 hours of embryonic development in 9 different animal species: (From left to right) Zebrafish, Sea urchin, Black widow spider, Tardigrade, Sea squirt, Comb jelly, Parchment tube worm, Roundworm, Slipper snail. Credit to @tessamontague.bsky.social & Zuzka VavruΕ‘ovΓ‘. #ZebrafishZunday #devbio πŸ§ͺ

08.03.2026 09:50 πŸ‘ 224 πŸ” 59 πŸ’¬ 3 πŸ“Œ 5
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🚨 #postdoc to be hired in the Paluch Lab 🚨

If you know anyone experienced with and, more importantly, excited about nanoscale architecture of #actincortex and super-res & electron #microscopy do encourage them to applyπŸ‘‡

Amazing colleagues, can only recommend πŸ˜‰

www.cam.ac.uk/jobs/researc...

03.03.2026 15:50 πŸ‘ 12 πŸ” 12 πŸ’¬ 0 πŸ“Œ 0
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Preprint Editors – Development's next step into the preprint landscape Summary: This Editorial announces a call for Preprint Editors in Development to help expand the journal's relationship with preprints by curating our β€˜In preprints’ articles.

New from @dev-journal.bsky.social: we're launching a new initiative and hiring Preprint Editors to help navigate the growing world of preprints in developmental & stem cell biology

Join our community & shape the future of research

journals.biologists.com/dev/article/...

02.03.2026 14:54 πŸ‘ 55 πŸ” 39 πŸ’¬ 1 πŸ“Œ 0

Stretching drives Membrane Homogenization of Phase-Separated Supported Lipid Bilayers https://www.biorxiv.org/content/10.64898/2026.02.26.708304v1

01.03.2026 01:48 πŸ‘ 5 πŸ” 3 πŸ’¬ 0 πŸ“Œ 2
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New preprint @biorxiv-devbio.bsky.social by Harshath Amal and colleagues from our lab @uni-muenster.de shows how a BMP #morphogen gradient is translated into graded junctional permeability by tuning adhesion and actomyosin contractility in #Drosophila
See tinyurl.com/yhbwd9xh
@sfb1348.bsky.social

18.02.2026 08:43 πŸ‘ 80 πŸ” 29 πŸ’¬ 4 πŸ“Œ 1
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Mapping life’s disparity and evolutionary constraints in a geometric complexity space Life’s diversity is limited to a small set of shapes due to fundamental physical and evolutionary constraints.

Avec Guillaume Dera, premier auteur de l'Γ©tude. www.science.org/doi/10.1126/...

18.02.2026 06:36 πŸ‘ 10 πŸ” 2 πŸ’¬ 0 πŸ“Œ 1
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Le vivant n’explore mΓͺme pas 1 % des formes possibles Des bactΓ©ries aux arbres, des coraux aux oiseaux, la vie terrestre semble d’une diversitΓ© infinie. Pourtant, une nouvelle Γ©tude parue dans Science Advances montre que la vie terrestre n’explore qu’une...

Des bactΓ©ries aux arbres, des coraux aux oiseaux, la vie terrestre semble d’une diversitΓ© infinie. Pourtant, une nouvelle Γ©tude montre que le vivant n’explore qu’une infime fraction des formes thΓ©oriquement possibles.
🦌🐊🌴🐠🐌
(et oui, j'ai passΓ© le Roi Lion Γ  la fin, faut savoir se faire plaisir)

18.02.2026 06:36 πŸ‘ 60 πŸ” 21 πŸ’¬ 1 πŸ“Œ 0

Weβ€˜re looking for a motivated Master student to join our team!

Do you want to optogenetically control metabolic activity to see how metabolism affects patterning and morphogenesis? πŸ’‘πŸ§«πŸ§¬πŸ”¬

Then please apply!
#optogenetics #metabolism #devbio #hESCs

Please RT. Thank you!πŸ™

17.02.2026 18:21 πŸ‘ 38 πŸ” 39 πŸ’¬ 0 πŸ“Œ 0
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πŸ“„ In cells, osmotic shocks shift Flipper-TR lifetime consistently with increased or decreased membrane tension, provided composition is controlled. This paper also compared quantitatively tether force and F-TR lifetime measurements @chloeroffay.bsky.social

πŸ”— bsky.app/profile/epim...

08.02.2026 07:59 πŸ‘ 6 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0

🀣🀣🀣 Cellmask is still my forever passion!

03.02.2026 11:36 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Cell membranes sustain phospholipid imbalance via cholesterol asymmetry This work challenges a major assumption in cell biology by showing that lipid bilayers can have drastically different phospholipid abundances between their two leaflets. This lipid abundance asymmetry...

interesting read😯
www.cell.com/cell/abstrac...

03.02.2026 00:56 πŸ‘ 13 πŸ” 7 πŸ’¬ 1 πŸ“Œ 0
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Advanced grad students + postdocs: apply for the 2026 #kitpqbio summer course, "Physical Principles of Morphogenesis in Plants and Animals," at buff.ly/OXXMKEv. Apply by Feb. 1.
Course directors Adrienne Roeder (Cornell) and Sebastian Streichan (UCSB)

19.11.2025 23:45 πŸ‘ 36 πŸ” 26 πŸ’¬ 0 πŸ“Œ 4
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@marineluciano.bsky.social recreates intestinal Villi geometry by growing epithelial cells on wavy rolling substrates. Unexpected intrication of curvature effects is observed. Thanks to all! @caterinatomba.bsky.social @sgabriele.bsky.social @sciencesunige.bsky.social
www.biorxiv.org/content/10.6...

20.01.2026 10:24 πŸ‘ 51 πŸ” 17 πŸ’¬ 1 πŸ“Œ 2

πŸ˜‚πŸ˜‚

19.01.2026 07:52 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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a woman says " would you like to join us " with her eyes closed ALT: a woman says " would you like to join us " with her eyes closed

πŸ“’ Open faculty position – Origins of Life
We have an opening in our section at the University of Geneva! πŸ§¬πŸš€

SPREAD THE WORD

Apply here: jobs.unige.ch/www/wd_porta...

16.01.2026 17:49 πŸ‘ 45 πŸ” 39 πŸ’¬ 1 πŸ“Œ 1
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Feb 1 deadline approaching for our @kitp-ucsb.bsky.social QBio summer course on Physical Principles of Morphogenesis in Plants and Animals. @streichan.bsky.social
@maurazimmermann.bsky.social @maizel-lab.org @yusuke-mori.bsky.social @akankshi.bsky.social @nicolettapetridou.bsky.social

13.01.2026 23:36 πŸ‘ 25 πŸ” 20 πŸ’¬ 1 πŸ“Œ 1
CEL - Concours Chercheurs - DΓ©pΓ΄ts des recommandations

CNRS assistance replied: there is a website to send around survey.cnrs-dir.fr/index.php/16...

09.01.2026 07:49 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Should I obtain the URL to send it to the people? Because I found no form for email adress either. Thanks!!

08.01.2026 18:20 πŸ‘ 0 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0

*HELP* Someone found how to include *avis de personnalitΓ©s* in the @cnrs.fr website for the Concours chercheurs? Thanks, I have nothing to offer, Austria does not have galette des rois

08.01.2026 17:30 πŸ‘ 0 πŸ” 2 πŸ’¬ 2 πŸ“Œ 1

Lipid-mediated reinforcement of FGF/MAPK signaling enables robust otic placode specification https://www.biorxiv.org/content/10.64898/2026.01.06.698011v1

08.01.2026 03:31 πŸ‘ 1 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Genetically engineered ESC-derived embryos reveal Vinculin-dependent force responses required for mammalian neural tube closure https://www.biorxiv.org/content/10.64898/2025.12.22.696028v1

25.12.2025 18:30 πŸ‘ 4 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0
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Can biological tissues "learn"? Our new preprint shows that epithelial tissues exhibit emergent behaviors akin to unsupervised learning. Local tension remodeling allows cell networks to store long-range memory and program global elasticity properties.

Read more here: www.biorxiv.org/content/10.6...

20.12.2025 15:56 πŸ‘ 31 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0
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This movie shows lysosomes (orange) and keratin (gray) in a cultured cell over 10 minutes.

12.12.2025 06:20 πŸ‘ 267 πŸ” 42 πŸ’¬ 11 πŸ“Œ 3
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Keeping up with the neighbours: local synchronisation of cell fate decisions during development - EMBO Reports Even before the advent of multicellular life, unicellular creatures would communicate with their neighbours to coordinate their behaviours. Multicellular organisms have the particular challenge of orc...

Hello, here is a review I wrote about how cells sometimes try to synchronise with surrounding cells so that they can do a good job of building tissues during development. It is called "Keeping up with the neighbours"

link.springer.com/article/10.1...

#DevBio πŸ§ͺ

11.12.2025 15:19 πŸ‘ 58 πŸ” 18 πŸ’¬ 0 πŸ“Œ 2

Lipid-induced Caveolin1-Lipid droplet trafficking is associated with lipid droplet growth https://www.biorxiv.org/content/10.64898/2025.12.10.693432v1

10.12.2025 22:30 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1
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#RejoignezLeCNRS 🫡 Les concours chercheurs CNRS 2026 ouvrent le 8/12 !
Envie de faire avancer la science au sein d’un des plus grands organismes de recherche ?
πŸ‘‰ carrieres.cnrs.fr/concours-...

#ConcoursChercheurs #Science #Recherche #Icicarecrute #recrutement

25.11.2025 10:02 πŸ‘ 32 πŸ” 41 πŸ’¬ 3 πŸ“Œ 5
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SY-Stem 2026 is here! The symposium focusing on the next generation of stem cell researchers returns to the Vienna BioCenter from 11–13 March 2026. Register online: sy-stem.org

10.12.2025 16:10 πŸ‘ 15 πŸ” 8 πŸ’¬ 1 πŸ“Œ 1
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Ovarian folliclesπŸ₯šare influenced by biochemical signals and the physical mechanics of their surroundings.

A study from Joe Chan's group (NUS) reveals that surface stiffness and internal compressive stress are key for follicle development.

πŸ“–Read more: https://go.nature.com/4ptpMvE

10.12.2025 08:11 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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SAVE THE DATE! Stoked to organize the 2026 Santa Cruz Developmental Biology Meeting with @rashmi-priya.bsky.social, @lowelab.bsky.social, and Shelbi Russell. Come learn about Biomedicine, Biomechanics, and the Biosphere, August 24-28, 2026. Registration dates, etc., coming soon! Please RT

19.11.2025 20:23 πŸ‘ 119 πŸ” 75 πŸ’¬ 1 πŸ“Œ 3