Laboratory for Stem Cells and Cancer Research

We are looking for an enthusiastic PhD student to join our lab (labriccardofodde.nl) to investigate how mechanical forces drive DNA damage and transcription stress in non‑dividing cells. Applications must be submitted exclusively via: www.werkenbijerasmusmc.nl/en/vacancy/1....

How I confronted my growing cynicism about academia—and rekindled my sense of purpose “Maintaining hope doesn’t mean ignoring hardships or naïvely expecting things to work out,” this professor writes

How I confronted my growing cynicism about academia—and rekindled my sense of purpose | Science | AAAS www.science.org/content/arti...

Mathijs Verhagen, my 20th PhD student (and presumably the last one!), brilliantly defended his cum laude PhD thesis "Catching a moving target".

You can download the e-version of his thesis from here: drive.google.com/file/d/1MLYa...

and this is the video-link:
youtube.com/live/vZZKAdR...

Choose Europe for Science: ERC welcomes new budget for 'super grants' The Scientific Council of the European Research Council welcomes the offer of substantial additional budget from the European Commission for the development of a new ERC funding instrument offering la...

Choose Europe for Science: ERC welcomes new budget for 'super grants'|ERC erc.europa.eu/news-events/...

The nucleosome remodeling and deacetylase-SWItch/sucrose non-fermentable antagonism regulates the coordinated activation of epithelial-to-mesenchymal transition and inflammation in oral cancer AbstractBackground. Phenotypic plasticity and inflammation, 2 well-established hallmarks of cancer, play key roles in local invasion and distant metastasis

just out @JNCI
doi.org/10.1093/jnci...

JNCI: Journal of the National Cancer Institute has accepted Roberto Stabile's last manuscript entitled "The NuRD-SWI/SNF antagonism regulates the coordinated activation of EMT and inflammation in oral cancer" for publication. Congrats and thanks to Roberto, our lab, and all the collaborators.

At the moment, mansion-sized Asteroid 2024-YR4 has a one-in-fifty chance of hitting Earth in the next eight years.

Now might be a bad time to reduce spending on Science. Just sayin’.

American chaos: standing up for health and medicine Withdrawal from WHO and the Paris Agreements. USAID shuttered and aid halted, ceasing health programmes globally. A freeze on US$3 trillion worth of federal grants and loans, jeopardising the function...

American chaos: standing up for health and medicine - The Lancet www.thelancet.com/journals/lan...

Unborn Babies Use Genes From Dad to “Remote-Control” Mothers for Extra Food Scientists at Cambridge have unveiled a fascinating mechanism where fetuses use a paternal gene to control the mother's nutrient release during pregnancy. This "remote control" system involves hormona...

Unborn babies use genes from dad to remote control mothers for extra food #Igf2 #imprinting scitechdaily.com/unborn-babie...

we pay, we write, we review… they profit

Happy Birthday Dr.Fauci and thank you for saving us! 💙

How to produce a first-class paper that will get published, stand out from the crowd and pull in plenty of readers

www.nature.com/articles/d41...

Non-stem cell lineages as an alternative origin of intestinal tumorigenesis in the context of inflammation - Nature Genetics Upon inflammation and targeted gene mutation, some fully differentiated secretory and postmitotic intestinal epithelial lineages dedifferentiate to acquire stem-like features and promote tumor formati...

www.nature.com/articles/s41...

Western lifestyle, metaflammation and the cell of origin of colon cancer - Nature Reviews Gastroenterology & Hepatology Western lifestyles cause a low-grade but chronic and metabolic inflammation (or metaflammation), which might prime committed cell lineages to initiate colon tumorigenesis. At-risk individuals might in...

www.nature.com/articles/s41...

How a silly science prize changed my career A levitating frog, a necrophiliac duck, taxi drivers’ brains — the Ig Nobel prizes have shined a spotlight on offbeat work. Here’s an inside look at how winners feel about this sometimes unwanted ‘hon...

www.nature.com/articles/d41...

Meta loses ground to #Bluesky as users abandon Elon Musk’s X

👉 interesting update from the Financial Times 🧪

#scientificcommunity
#STEM #Research #Education #Science #Academics #safeplace

www.ft.com/content/e1b5...

And while we are trying to demonstrate how Western-style diet is underlying many non-communicable disease including cancer, these 5 morons eat a BigMac on their private jet doi.org/10.1038/s415...

Human Tumor Atlas Network (HTAN) The Human Tumor Atlas Network (HTAN) is constructing 3-dimensional atlases of the cellular, morphological, molecular, and spatial features of human cancers (and their surrounding microenvironments) ov...

Super cool for so many of us ➡️ The Human Tumor Atlas Network (HTAN) is constructing 3D atlases of the cellular, morphological, molecular, and spatial features of human #cancers (and their #microenvironments) over time 🧪

#mechanobiology #microscopy #physicsoflife

www.cancer.gov/about-nci/or...

a man in a lab coat is standing in front of a computer with the caption good to see you guys again ALT: a man in a lab coat is standing in front of a computer with the caption good to see you guys again

WTF is going on here at Blue Sky? People are civil to each other. People having intelligent discussions. People are spelling things correctly. I haven’t seen any racism or sexism.

I’m confused.

Researchers say diabetes treatment breakthrough could lead to end of insulin injections Researchers at the Baker Heart and Diabetes Institute say they've discovered a way to make pancreatic cells produce insulin using existing cancer drugs.

The Baker institute in Melbourne has potentially discovered a new diabetes treatment by using cancer treatment drugs to stimulate the production of insulin in people’s existing pancreatic stem cells. Next stage is pre-clinical trials on animals

Western lifestyle, metaflammation and the cell of origin of colon cancer - Nature Reviews Gastroenterology & Hepatology Western lifestyles cause a low-grade but chronic and metabolic inflammation (or metaflammation), which might prime committed cell lineages to initiate colon tumorigenesis. At-risk individuals might in...

www.nature.com/articles/s41...

Non-stem cell lineages as an alternative origin of intestinal tumorigenesis in the context of inflammation - Nature Genetics Upon inflammation and targeted gene mutation, some fully differentiated secretory and postmitotic intestinal epithelial lineages dedifferentiate to acquire stem-like features and promote tumor formati...

www.nature.com/articles/s41...