Urbain Weyemi, Ph.D.

Thank you, Kevin! Please do.

Peroxiredoxin 1 safeguards the nucleolar genome from oxidative damage Peroxiredoxin 1 (PRDX1) is a highly conserved, thiol-dependent peroxidase that rapidly scavenges reactive oxygen species to modulate redox signaling. PRDX1-null mice exhibited genomic instability, sho...

🚨 Preprint Alert! 🚨
Ever wondered how the nucleolar genome is protected from oxidative damage?
Check our new preprint uncovering a previously unrecognized role of Peroxiredoxin 1 (PRDX1) in safeguarding ribosomal DNA (rDNA) from oxidative damage.

www.biorxiv.org/content/10.1...

The (molecular) shape of you New methods allow scientists to use a powerful technique known as cryo-EM to examine proteins that have been difficult to study so far.

🧪 A new method called MagIC-Cryo-EM allows scientists to use powerful #CryoEM techniques to examine proteins that have been difficult to study so far.

FYI - We've extended abstract submission deadline to June 8. Submit soon to be considered for a short talk. Come join us at the first FASEB #Ferroptosis meeting! It's going to be awwwwesome! 🤩
events.faseb.org/event/11797f...

Celebrating my brother’s graduation at The George Washington University for his Master of Engineering in Cloud Computing!

Brother Jacques, you made us proud! Your hard work paid off! 🎉👏🏽👏🏽👏🏽

Reminder: The 1st FASEB #Ferroptosis Meeting is this summer! Spectacular speaker lineup + short talks selected from submitted abstracts. It is going to be awesome! Trainees, newcomers & all interested are welcome!
📅 Abstract deadline: June 1, 2025.
shorturl.at/QA6T1

The spring is back for real in Maryland!

The Jiang lab@Moffitt is attending @ASBMB! If you are interested in redox biology and cancer metabolism, check out our posters as listed below on Monday, April 14th, 2025! See you in Chicago! We are hiring now!

Check out our new review paper in @cp-cellreports.bsky.social
We summarized recent advances in understanding the complex interplay between DNA damage response and metabolism, focusing on how this crosstalk affects cancer therapy resistance.
www.cell.com/cell-reports...

Abstracts are due TOMORROW! Please share!

Targeting two proteins leaves some cancer cells vulnerable to chemotherapy | Center for Cancer Research Targeting two proteins that cancer cells rely on to sustain their metabolism and DNA repair capabilities can double the survival rate of mice with lung cancer tumors. Cross referencing with data from ...

I thank the NCI Center for Cancer Research for shedding light on our most recent publication.

ccr.cancer.gov/news/article...

This is great news! Congratulations!

Joyeux Anniversaire!

To all the charlatans bragging about curing cancer in 5 years with AI: you have no idea what you’re taking about.

I was hoping that my first bsky post would be more cheerful. I recently joined NIH (NIEHS) as a PO. I fought hard for this position and was so excited to support health science from a new vantage point… I picked up my life and moved to NC. Unfortunately, my time at NIEHS was short lived.

TIRING!

Merci d’avoir partagé!

Happy Black History Month!

Je pense que c’est sous-estimer l’histoire de ce pays, particulièrement les luttes des années 60. Attendons de voir la suite. Vous avez peut-être raison. L’histoire nous le dira.

Whenever you hear someone sneer about scientific research that seems useless to them — “they’re studying the spit of lizards?!” — remind them that’s exactly how we got Ozempic.

globalnews.ca/news/9793403...

Thank you, dear Antonio! We cannot exclude the possibility of Prx2 phenocopying Prx1. Our models have low to undetectable Prx2. Given their structural and localization similarities (i.e., nuclear), I would not exclude this possibility. More to come…

Thank you, Barak!

Metabolic dependency mapping identifies Peroxiredoxin 1 as a driver of resistance to ATM inhibition Metabolic pathways fuel tumor progression and resistance to stress conditions including chemotherapeutic drugs, such as DNA damage response (DDR) inhi…

Check out our new paper just out in Redox Biology!
Leveraging metabolism-focused CRISPR screen, we established a gene dependency map between DNA damage response and metabolism.
We identified peroxiredoxin 1 as a key driver of resistance to ATM inhibition.

www.sciencedirect.com/science/arti...

Please keep the hope alive.

Please don’t. I know I am too optimistic, but think about our journey as a pendulum.

Excited to co-chair #ASBMB2025 with the incredible
Dave Pagliarini! This year’s ASBMB meeting promises to showcase cutting-edge science, foster dynamic collaborations, & inspire new ideas. Don’t miss your chance to be part of it—register & submit your late breaking abstracts. t.co/UwgMdxBo15

About 10 minutes after your first chalk talk with comments like:
I don’t see how your work is going to reshape the field. Of course, I don’t know either. 😂😂

Fake news! Please read the entire study. It is fluoride over-exposure, and it is a 1.6 drop in IQ. I don’t want to lose my teeth to adjust to a standard deviation.

The U.S. Surgeon General wants cancer warnings on alcohol. Here's why Drinking alcohol raises the risk of developing seven types of cancer, according to a new advisory from U.S. Surgeon General Vivek Murthy.

Drinking alcohol raises the risk of developing seven types of cancer, according to a new advisory from U.S. Surgeon General Vivek Murthy.

Emmanuelle Bignon on LinkedIn: Job offer - pdoc CHROM 📢🧬I have a postdoc position open for people with experience using QM/MM on biosystems! Do not hesitate to apply if you're interested in investigating the…

First post here, how exciting!! 🥳
📣💻[JOB OFFER] I am looking for a postdoc with experience in QM/MM, MD and biosystems, and who would be motivated to study the formation mechanisms of oxydative histone modifications. Please share! #compchem #histones #PTM #redox
www.linkedin.com/posts/activi...