Great collaboration between University of Hamburg and the team of Moussa Benhamed from the Institute of Plant Sciences-Paris-Saclay driven by @tuncayhasibe.bsky.social
Great collaboration between University of Hamburg and the team of Moussa Benhamed from the Institute of Plant Sciences-Paris-Saclay driven by @tuncayhasibe.bsky.social
BUT: restoring MER3 can partly rescue fertility. With DREAMβs role conserved from plants to animals, weβre excited to shed light on how reproduction is orchestrated across multicellular life! π±π¬β¨ #Meiosis #Science #PlantBiology
www.biorxiv.org/content/10.1...
How do plants control the genes needed for successful sexual reproduction? Our new work uncovers the DREAM complex as a crucial regulator of meiotic recombination in Arabidopsis. Without DREAM, plants are sterileβkey recombination genes like MER3 are switched off...
Breaking genetics newsβΌοΈπ±π½ A natural DNA trick triples recombination in maize. What we first saw in Arabidopsis (@hendersi lab) a decade ago is now confirmed in cropsβopening new doors for plant breeding. Published today in Nature Plants! More details π www.nature.com/articles/s41...
Happy lab reunion over Italian cross-over dinner with Chao Yang from Huazhong Agri Uni π¨π³βin town to share insights on meiotic recombination in rapeseed π±.
7 nations, 1 table. Science unites ππ¬ #ScienceCommunity #LabLife
In WT plants, expansion microscopy with spindle immunolabeling showed microtubule connections between spindle poles and the apicobasal cortex.
Thanks Yaniv. Very kind.
The identification of the very conserved CTF18, SGO2 and SPF2 as suppressors of centromere-proximal crossovers highlights the importance of cohesin turnover in this process and opens up new possibilities for plant breeding.βMuch more in the paper : www.biorxiv.org/content/10.1...
Six more yearsβplus a lot of blood, sweat, and tearsβlater, we are thrilled to finally share it: a cytological framework of female meiosis in Arabidopsis!
www.biorxiv.org/content/10.1...
This led to our first live cell imaging paper on Arabidopsis meiosis in 2019 elifesciences.org/articles/42834.
What we learned from the male side brought us back to our original question, and so began another chapter.
After 12 yearsβ¦
In 2014, a wild idea was born: to follow female meiosis in Arabidopsis in real time. After many trials (including experiments with quirky mutants where female organs developed inside out, and a few other unconventional ideas), we switched gears to image the male side.
Fantastic collaboration with colleagues from Hungary and the Netherlands.
www.cell.com/iscience/ful...
While a complete knockout is lethal, meiosis-specific reduction of TTN9 causes striking chromosome segregation issues and abnormal centromere signals during meiosis I. Our findings support a conserved role for Csm1-like proteins in maintaining healthy chromosome segregation across eukaryotes.
Second: Some new findings about chromosome segregation in Arabidopsis!
Weβve characterized TITAN9 (TTN9), a distant Csm1-like protein in Arabidopsis. Proteomics revealed TTN9 associates with multiple kinetochore components, including DSN1.
Our work highlights an important role for stress granules during meiosis in response to heat stress.
This paper is also the first one from our local research network BIKON studying biomolecular condensates in Hamburg.
www.science.org/doi/10.1126/...
Interestingly, this behavior is specific to TAM; other meiotic cyclins do not form such condensates.
Crucially, we found that TAMβs recruitment to these granules enables plants to proceed to the second meiotic division under challenging conditions.
First up: understanding how plants defend themselves against heat stress. Our recent Science Advances paper shows that the meiotic cyclin TAM localizes to stress granulesβspecial biomolecular condensatesβduring meiosis.
Weβve been a bit quiet here due to the climate around social media in politics. But behind the scenes, weβve made some exciting progress and are happy to share several new papers!
As seen on our kitchen cupboard:
Happy lunar year!
Celebrating with our team the year of the...
Very cool project for a Ph.D. student in the team of our neighbors here at the Institute for Plant Science and Microbiology, University of Hamburg @uni-hamburg.de. Highly recommended.
Here, an open PhD position to study the structure and dynamics of bimolecular condensates in plant cells by Cryo-EM and super resolution microscopy.
Please spread the word.
www.uni-hamburg.de/stellenangeb...
#plantscience
Getting ready for the winter term - the calm before the storm...
Here, a job advert for junior group leader position in Molecular Biology of Plants, especially with focus on cell division, cell cycle, chromosomes and DNA repair.
Please spread the word.
stellen.uni-hamburg.de/jobposting/d...
Thanks a lot!
Thanks!
To start with, and perhaps as a sign for a new beginning, some picts from yesterdayβs polar light magic over Hamburg.
The Schnittger lab is located in Hamburg/Germany and represents an international team of cell biologists, molecular biologists, and biochemists investigating the cell cycle, meiosis and DNA damage in plants. Here, we will post the latest information from and about the lab.
The Schnittger lab is happy to join BlueSky. We just re-located from the former twitter platform that became unbearable for us to support due to the homophobic, unsocial and democracy-threatening behavior of its new owner.