We're excited to announce that registration for our upcoming Spatial Omics workshop has opened!
Details in π§΅
We're excited to announce that registration for our upcoming Spatial Omics workshop has opened!
Details in π§΅
A Visual Guide to DNA Sequencing.
Learn how different DNA sequencing technologies work, from Sanger sequencing to Illumina to nanopores. (Complete with illustrations!)
Written by Evan DeTurk. Illustrated by Ella Watkins-Dulaney.
π¨Next DevBioConnect on the way
Developmental Biology Author webinar featuring Dr. Diana L. Carlone & Dr. Emil Kriukov π·
ποΈMar. 10th, 2026
β°11 amβ12 pm CST
docs.google.com/forms/d/e/1F...
@socdevbio.bsky.social
www.sdbonline.org/meeting?Reso...
Development presents... Wednesday 25 February β 15:00 GMT/UTC Chair: Polina Kameneva JoaquΓn Navajas Acedo (University of Basel) βSpatiotemporal emergence of somatosensory neuron diversityβ Carlo Donato Caiaffa (Universidade de SΓ£o Paulo) βDecoding the role of HNRNPH2 in neural development using brain organoids and antisense oligonucleotidesβ Clarisse Brunet (Institut Curie) βDecoding the gliogenic switch: how human brain organoids reveal the secrets of glial cell fateβ #DevPres @dev-journal.bsky.social theNode.biologists.com/devpres The Company of Biologists logo Development logo QR code
π’Register for our #DevPres webinar on neurodevelopment
The webinar, chaired by Polina Kameneva, features talks from JoaquΓn Navajas Acedo @mads100tist.bsky.social, Carlo Donato Caiaffa & Clarisse Brunet @clarissebrunet.bsky.social.
ποΈ25 February, 15:00 GMT/UTC
us02web.zoom.us/webinar/regi...
The $100 whole human genome sequence finally reached!
www.sandiegouniontribune.com/2026/02/19/s...
We are very happy to see our study finally appear online @nature.com! This has been work of nearly 10 years in collaboration with the National Institute of Genome Medicine π²π½, the National Cancer Institute π²π½, the @sangerinstitute.bsky.social and others β¬οΈ
www.nature.com/articles/s41...
π§΅ 10 free bioinformatics tools you should know in 2026. These will save you time, money, and headaches.
anndataR: converting single-cell data, from R to python and back tomsing1.github.io/blog/posts/a... #Rstats
Demystifying Oral Epithelial Dysplasia: a histological guide
Enhanced interpretation of WHO 28 features
Normal oral mucosa variants
Core architectural & cytologic abnormalities
#Pathology 2024
www.pathologyjournal.rcpa.edu.au/article/S003...
Mosaic partial epidermal reprogramming remodels neighbors and niches to refine skin homeostasis and repair @natcomms.nature.com
www.nature.com/articles/s41...
New paper out today, 'Global North-South science inequalities due to language and funding barriers'
We highlight how language and funding barriers can compound inequity and offer practical recommendations to bridge these gaps.
Read the Open Access paper here! π tinyurl.com/654ztk3w
Neural crest contribution to craniofacial structures and phenotypic variation
#DBfeature
Bones, brains, and biasβneural crest cell contribution to craniofacial structure
Active Learning Assignments for craniofacial perception & normal phenotypic variation
by Jeffrey Carmichael, Diane Darland et al
www.sciencedirect.com/science/arti...
Figure 2 The dimensions of cancer CREDIT Hanahan - Cell.
An update to the Hallmarks of Cancer framework for understanding (and researching) what causes human cancers. spkl.io/63321Aqwbc
Douglas Hanahan
@cp-cell.bsky.social
Review @natprot.nature.com @garybader.bsky.social
Tutorial: annotation of animal genomes
www.nature.com/articles/s41...
EGFR signaling in the tissue around oral cancers increases nerve sensitivity and impairs opioid efficacy
www.science.org/doi/10.1126/...
This review reflects on a journey Iβve been lucky to witness closely:
βΌοΈ The transformation of single-cell proteomics from a fragile idea into a powerful discipline.
The technological progress towards deeper coverage and higher throughput is fast and exciting, but what excites me most is ...
1/n
π¨Next DevBioConnect on the wayβΌοΈ
Developmental Biology Author webinar
by Dr. Alexa Burger & Dr. Robert Huebner
ποΈ Feb 10th, 2026
β° 11 amβ12 pm CST
To Register
forms.gle/4J192L42y6sg...
@socdevbio.bsky.social
@aburger2009.bsky.social
#SpatialTranscriptomics
Visium
+ scRNAseq
Oral Squamous Cell Carcinoma
vs paired Oral Leukoplakia vs normal tissues
Inhibin A+ monocyte enriched in premalignant OLK lesions
1β£Mesenchymal CAF 2β£APOE+NRG1+ MΟ 3β£TNFRSF4+ Treg β¬οΈwith tumor progression
#CellDiscov 2023
www.nature.com/articles/s41...
Our review βA competition model of multilineage priming and cell-fate decisionsβ is out: www.cell.com/cell-reports...
Peer Bork died yesterday π which shocked me. In 2003 I did a short-term fellowship in Peerβs lab because I idolized him. I met Martin there & we wrote this paper together. Peer was great at bringing people together; a master collaborator with a rare ability to think up big ideas.
Non-negative matrix factorization is a commonly used technique in genomics data analysis.
Read my tutorial on how you can use it for single-cell RNAseq data divingintogeneticsandgenomics.com/post/matrix...
Chinese cell atlas reveals surprising immune variation among peoples @nature.com
www.nature.com/articles/d41...
www.nature.com/articles/s41...
Growth factors secreted by sensory nerves promote fracture healing @science.org
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Cartoon of Pax9 expression (purple) during facial development in mouse (left) and zebrafish (right). Text: Mammals. Pax9 is expressed In tooth-forming mesenchyme around the mouth. Required for tooth formation in mouse and human. Fish. Pax9 is also expressed in oral mesenchyme in fishes. But many fish do not form oral teeth. Vestigial expression or divergent function? Result: pax9 is required for formation of upper jaw bones and barbels in zebrafish, but dispensable for non-oral teeth. Support ancestral function in building peri-oral structures from condensed mesenchyme rather than a specific requirement for teeth
#DBfeature π
Pax9 has a broader role in initiating development of mesenchymal structures around the mouth during zebrafish development
By Sandhya Paudel, Sarah McLeod, Stefani Gjorcheska, Lindsey Barske
tinyurl.com/yc3jfpux
Portrait of Brenna Henn next to an open freezer of samples.
Here's my latest contribution to the @nytimes "Lost Science" series. Brenna Henn's sweeping study of African genetics has been frozen. Gift link: nyti.ms/3Ypmm1A
WaveOrder is a powerful new #microscopy tool from Biohub that helps researchers reconstruct messy microscope data into clean, quantitative maps. Itβs grounded in physics & itβs already changing how we see biology.
π Preprint https://bit.ly/4jgDJLB
π¬WaveOrder: https://czi.co/4pMwGgb
My statement on President Trumpβs actions in Venezuela.
Modern biology research is biased towards investigating genes that are widely conserved and present in humans. What about genes that ARE widely conserved but NOT present in humans? Can genes missing from humans tell us something about what makes our biology different from that of other animals? 1/8
Systematic cell-type resolved transcriptomes of 8 tissues in 8 lab and wild-derived mouse strains capture global and local expression variation
www.cell.com/cell-genomic... @ucirvine.bsky.social