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Holmes Lab

@holmeslab-bhi

The Holmes Lab works to understand the genetic and brain bases of individual differences in network organization across psychiatric illness. πŸ“Rutgers, Center for Advanced Human Brain Imaging Research holmeslab.rutgers.edu

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22.11.2024
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Latest posts by Holmes Lab @holmeslab-bhi

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Looking for a post-bac RA position focused on the brain bases of affective and psychotic illness?
@holmeslab-bhi.bsky.social is hiring!
@cahbir.bsky.social @rutgersbhi.bsky.social @rutgersu.bsky.social @sobp-org.bsky.social @hitop-system.bsky.social @ohbmofficial.bsky.social

11.11.2025 15:48 πŸ‘ 34 πŸ” 27 πŸ’¬ 2 πŸ“Œ 3
Flyer to join Holmes Lab

Flyer to join Holmes Lab

The Holmes Lab is #hiring a full-time research assistant/predoc! Our work focuses on functional brain networks-- how they change, how they are impacted in psychiatric illness, and much more!
Please rt and reach out if you’re interested πŸ‘€
Find out more holmeslab.rutgers.edu

11.11.2025 16:50 πŸ‘ 8 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0
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Holmes Lab + Parkes Lab had a great fall social a few weeks back!! Pottery painting (including an awesome brain-art mug by @ambrains.bsky.social 🧠). Thank you to our awesome mentors @avramholmes.bsky.social and @lindenmp.bsky.social for encouraging these great lab events! πŸ’«

07.10.2025 16:16 πŸ‘ 12 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0
Human Neuroimaging Faculty Positions in Rutgers Brain Health Institute The Center for Advanced Human Brain Imaging Research (CAHBIR), a component of the Rutgers Brain Health Institute (BHI) on the Busch campus in Piscataway, NJ, is recruiting for two open rank (Assistant...

The @cahbir.bsky.social and @rutgersbhi.bsky.social are hiring! Multiple open area and open rank faculty jobs, wonderful colleagues, amazing resources, and one of the largest communities of brain science research groups on the planet. Please apply and share widely.

jobs.rutgers.edu/postings/209...

05.09.2025 19:58 πŸ‘ 8 πŸ” 7 πŸ’¬ 1 πŸ“Œ 1
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The cellular associates of late life changes in white matter microstructure The microstructural architecture of white matter supporting information flow across local circuits and large-scale networks changes throughout the lifespan. However, the genetic and cellular factors u...

Latest
@holmeslab-bhi.bsky.social
preprint. Here, integrating genetic, post-mortem, and diffusion MRI data, Rowena Chin examines the heritability and cellular associates of late-life decline in white matter integrity.
@cahbir.bsky.social @rutgersbhi.bsky.social

www.biorxiv.org/content/10.1...

04.09.2025 19:11 πŸ‘ 11 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0

Great write up of the @nature.com study on MRI economics by @bttyeo.bsky.social's research group!

With @avramholmes.bsky.social @sidchop.bsky.social @carrisacocuzza.bsky.social

21.08.2025 15:07 πŸ‘ 11 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0

🚨Thrilled to share our latest work just published in @nature.com where we looked into the optimal fMRI scan time for brain-wide association studies (BWAS) 🧠⏱️! Full thread belowπŸ‘‡:

17.07.2025 02:22 πŸ‘ 14 πŸ” 8 πŸ’¬ 1 πŸ“Œ 0

This new Yeo Lab tool should immediately and permanently replace sample-size-only power calculations for functional MRI.

www.nature.com/articles/s41...

17.07.2025 11:16 πŸ‘ 56 πŸ” 16 πŸ’¬ 3 πŸ“Œ 0

Everyone should try out the Trandiagnostic Connectome Project (TCP) dataset! Openly available on @openneuro.bsky.social

17.07.2025 03:24 πŸ‘ 19 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
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Longer scans boost prediction and cut costs in brain-wide association studies - Nature Although the number of participants is important for phenotypic prediction accuracy in brain-wide association studies using functional MRI, scanning for at least 30 min offers the greatest cost effectiveness.

Nature research paper: Longer scans boost prediction and cut costs in brain-wide association studies

go.nature.com/3IME4aA

17.07.2025 10:35 πŸ‘ 32 πŸ” 8 πŸ’¬ 0 πŸ“Œ 1

And Amber @ambrains.bsky.social is killing it as the Art Exhibition Manager for the OHBM Brain Art SIG! 🎨

Major kudos to all of you, and have fun at the last day!! #OHBM

27.06.2025 23:59 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Ashlea @ashleasegal.bsky.social is doing amazing work as the Chair of the OHBM Student and Postdoc Special Interest Group (SP-SIG), which has also been putting out amazing programming all year long 😍

27.06.2025 23:59 πŸ‘ 8 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

Holmes Lab is representing at #OHBM2025! 🧡 Loic
@loiclabache.bsky.social presented in the Language: Anatomy, Networks and Pathology section with his paper on "The molecular and cellular underpinnings of human brain lateralization" 🧠

27.06.2025 23:59 πŸ‘ 5 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0

Check out our latest open data release. n=240, most with a dsm-5 dx with extensive phenotying (~100 scales/subscale), rest and task functional imaging. See @carrisacocuzza.bsky.social's thread below for deets and links πŸ‘‡πŸΎπŸ‘‡πŸΎπŸ‘‡πŸΎ

04.06.2025 23:45 πŸ‘ 10 πŸ” 7 πŸ’¬ 0 πŸ“Œ 1
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Convergent and divergent brain-cognition relationships during development revealed by cross-sectional and longitudinal analyses in the ABCD Study How brain networks and cognition co-evolve during development remains poorly understood. Using longitudinal data collected at baseline and Year 2 from 2,949 individuals (ages 8.9-13.5) in the Adolesce...

Very cool preprint examining how brain networks and cognition co-evolve during development
By @bttyeo.bsky.social @lucinauddin.bsky.social @avramholmes.bsky.social @elvisha.bsky.social & colleagues
πŸ§ͺ🧠
www.biorxiv.org/content/10.1...

07.06.2025 10:35 πŸ‘ 33 πŸ” 12 πŸ’¬ 1 πŸ“Œ 1

Check out my newest preprint to see the TCP dataset in action! 🀘🧠

Brain network dynamics reflect psychiatric illness status and transdiagnostic symptom profiles across health and disease: www.biorxiv.org/content/10.1...

04.06.2025 18:34 πŸ‘ 13 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0

If you missed it, our open source 240-person transdiagnostic dataset is now published. Read the data release πŸ‘‡πŸ‘‡ + find it on:
OpenNeuro: openneuro.org/datasets/ds0...
NDA: nda.nih.gov/study.html?i...

10.06.2025 13:51 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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The Transdiagnostic Connectome Project: an open dataset for studying brain-behavior relationships in psychiatry - Scientific Data Scientific Data - The Transdiagnostic Connectome Project: an open dataset for studying brain-behavior relationships in psychiatry

🚨 Dataset & Manuscript alert! 🚨 The Transdiagnostic Connectome Project (TCP) manuscript is now available @natureportfolio.nature.com Scientific Data! πŸŽ‰

www.nature.com/articles/s41...

🧡1πŸ‘‡

04.06.2025 18:30 πŸ‘ 31 πŸ” 17 πŸ’¬ 2 πŸ“Œ 4

Our latest @holmeslab-bhi.bsky.social data release is now "live!" Available on NDA and @openneuro.bsky.social and spearheaded by @carrisacocuzza.bsky.social, @sidchop.bsky.social, and Connor Lawhead.

04.06.2025 18:46 πŸ‘ 7 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0

Brain network dynamics reflect psychiatric illness status and transdiagnostic symptom profiles across health and disease https://www.biorxiv.org/content/10.1101/2025.05.23.655864v1

28.05.2025 11:15 πŸ‘ 3 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

New @holmeslab-bhi.bsky.social paper led by @carrisacocuzza.bsky.social. Brain dynamics across task and rest can be used to predict the presence of psychiatric illness (case/control status), diagnostic labels, and multi-dimensional symptom fingerprints. @rutgersbhi.bsky.social @rutgersu.bsky.social

30.05.2025 19:52 πŸ‘ 15 πŸ” 7 πŸ’¬ 1 πŸ“Œ 0

Check out Carrisa's new paper! An amazing investigation into brain network dynamics across psychiatric symptomsπŸ”₯πŸ”₯
+ using our new open dataset the Transdiagnostic Connectome Project (TCP) πŸ”› openneuro.org/datasets/ds0...

02.06.2025 15:41 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Great lab outing to Duke Farms yesterday! Happy spring from the Holmes + Parkes labs πŸ˜„ 🌸

With @lindenmp.bsky.social @avramholmes.bsky.social @carrisacocuzza.bsky.social @ahmadbeyh.bsky.social @loiclabache.bsky.social (+ Amber Howell & Rachel Cooper)

29.05.2025 17:08 πŸ‘ 11 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

We're searching for a lead Research MRI technologists at @cahbir.bsky.social! Please share and pass along to any/all interested folks.

20.05.2025 14:40 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Last month Linden Parkes and his team put out an amazing new work! They build on their network control theory model & improved whole-brain structure-function coupling

Check this 🧡 for a summary πŸ”₯

www.biorxiv.org/content/10.1...

24.05.2025 17:53 πŸ‘ 5 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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While the world burns, we cook up a new preprint! doi.org/10.1101/2025...

Biophysical modeling is a key tool to derive mechanistic insights into the brain. These models are governed by biologically meaningful parameters (unlike artificial neural networks), but the dirty secret ... 1/N

11.04.2025 01:35 πŸ‘ 102 πŸ” 38 πŸ’¬ 1 πŸ“Œ 4

Newest #preprint from Holmes lab postdoc @loiclabache.bsky.social πŸ”₯

15.04.2025 21:38 πŸ‘ 6 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

The molecular and cellular basis of human brain lateralization. Latest paper from @holmeslab-bhi.bsky.social led by @loiclabache.bsky.social. @rutgersbhi.bsky.social, @cahbir.bsky.social

12.04.2025 12:29 πŸ‘ 27 πŸ” 12 πŸ’¬ 1 πŸ“Œ 0

Check out the new article by our very own PI, Avram Holmes!

08.04.2025 21:04 πŸ‘ 6 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

"To make a meaningful contribution to #neuroscience, #fMRI must break out of its silo."

My latest attempt to convince you of the importance of multi-scale approaches for the study of the human brain.

08.04.2025 13:19 πŸ‘ 8 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0