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Megan O'Driscoll

@meganodris

Schmidt Science Fellow at the Geneva Center for Emerging Viral Diseases. Infectious disease epidemiology, serology & modelling

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18.12.2023
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Latest posts by Megan O'Driscoll @meganodris

With thanks to collaborators at PDU Cambridge, icddr,b Bangladesh and Institut Pasteur Paris @hsalje.bsky.social @scauchemez.bsky.social @noemielefrancq.bsky.social @gabribdsantos.bsky.social

18.12.2025 10:04 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Importantly, we find antigenic distance estimates to be consistent with genetic distances between pathogens, supporting this approach as a means of characterizing antigenic immune landscapes.

18.12.2025 10:04 πŸ‘ 2 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0

We apply this approach to a serological study of 10 arboviruses in northwest Bangladesh, inferring population transmission dynamics and cross-reactive relationships between pathogens.

18.12.2025 10:04 πŸ‘ 2 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

In this work we show that there is a wealth of information about antigenic relationships contained in the covariance structure of multi-pathogen serological studies, and that this can be used to account for cross-reactivity in seroprevalence estimates.

18.12.2025 10:04 πŸ‘ 3 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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The final piece of my PhD work is now published in Science Translational Medicine! We present a new framework to jointly infer epidemiological and antigenic parameters from multi-pathogen population serological studies🦠

www.science.org/stoken/autho...

18.12.2025 10:04 πŸ‘ 32 πŸ” 13 πŸ’¬ 1 πŸ“Œ 1
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The Incubation Periods of Mpox Virus Clade Ib | Annals of Internal Medicine Background: Mpox virus (MPXV) clade Ib, first detected in the Democratic Republic of the Congo (DRC) in September 2023, spread internationally within months, prompting an emergency declaration from th...

Our paper on the incubation periods of mpox clade Ib is out, with Javier-Perez Saez, @andrewazman.bsky.social @justinlessler.bsky.social Elizabeth Lee, @jackieknee.bsky.social @johnshopkinssph.bsky.social
www.acpjournals.org/doi/10.7326/...

12.12.2025 12:28 πŸ‘ 3 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

πŸ“’ Thrilled to see that our work on chikungunya virus (CHIKV) epidemiology in Brazil is out in @thelancetinfdis.bsky.social 🧡

01.12.2025 07:42 πŸ‘ 11 πŸ” 6 πŸ’¬ 1 πŸ“Œ 0
Job Details

We're hiring a modelling postdoc at PSI Oxford for two exciting projects: 1) modelling the early immune responses to Nipah vaccination, and 2) joining the PRESTO team working on immunobridging in vaccine evaluation studies.

tinyurl.com/5abbxrjh

Get in touch for more info! Deadline 4th August.

11.07.2025 11:32 πŸ‘ 16 πŸ” 12 πŸ’¬ 0 πŸ“Œ 2
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Postdoctoral positions in epidemic mathematical/statistical modelling - Research Job description We are recruiting postdocs to contribute to research projects in the Mathematical Modelling of Infectious Diseases Unit, at Institut Pasteur in Paris. The candidates will be expected t...

New postdoc positions with a number of exciting epidemic modelling projects opening in our Unit at @pasteur.fr in beautiful Paris. Deadline for applications: 26th June.
research.pasteur.fr/en/job/postd...

05.06.2025 05:22 πŸ‘ 55 πŸ” 66 πŸ’¬ 0 πŸ“Œ 3
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We are excited to announce our 2025 Schmidt Science Fellows! 32 early career researchers, nominated by the world’s leading research universities, who will take an interdisciplinary approach to advancing discovery schmidtsciencefellows.org/news/2025-fe...

02.04.2025 13:48 πŸ‘ 33 πŸ” 13 πŸ’¬ 0 πŸ“Œ 11
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Non-sexual community transmission of Mpox clade 1b in Uvira, eastern Democratic Republic of Congo: a descriptive study Abstract Introduction In September 2023, mpox clade 1b emerged in Kamituga, a mining zone in South Kivu, DR Congo, primarily through sexual transmission. This study investigates an mpox clade 1b outbr...

We demonstrate a major shift in mpox transmission, with household-driven spread disproportionately affecting children, a pattern, distinct from the clade II outbreaks in men who have sex with men and early clade Ib cases in Kamituga linked to heterosexual transmission
doi.org/10.1101/2025...

27.02.2025 11:10 πŸ‘ 3 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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The incubation periods of Monkeypox virus clade Ib Background Monkeypox virus (MPXV) clade Ib, first detected in Democratic Republic of the Congo (DRC) in September 2023, spread internationally within months, prompting a WHO emergency declaration. Dat...

Mpox Clade Ib incubation periods are longer than previous MPXV estimates and vary by exposure route, with shorter periods for sexual transmission. These differences suggest the need to revise post-exposure monitoring guidelines.
doi.org/10.1101/2025...

27.02.2025 10:49 πŸ‘ 5 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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The fight against cholera is far from over. This Bangladeshi scientist is at the front lines Firdausi Qadri hopes widespread use of cheap oral cholera vaccines can help vanquish an old scourge

www.science.org/content/arti...

10.02.2025 14:12 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Learning the fitness dynamics of pathogens from phylogenies - Nature Phylowave, an innovative phylogenetic approach, can identify the main circulating pathogen lineages with increased fitness and the associated genetic changes, enabling the timely identification of…

Incredibly excited to share that our manuscript was just published in @nature.com ! What a way to start the new year! πŸŽ‰
https://buff.ly/4gyYCzx

We present phylowave, a framework that enables to learn the fitness dynamics of pathogens from phylogenies.

🧡 A thread... 1/n
#IDSky #IDModelling

02.01.2025 08:03 πŸ‘ 215 πŸ” 87 πŸ’¬ 3 πŸ“Œ 4

Really excited to launch the new iteration of the Bakery as part of the Pathogen Dynamics Unit, co-led with @hsalje.bsky.social and @virologyhouldcroft.bsky.social Has been awesome working together this last year and really excited for things to come! Please follow and repost.

20.12.2024 12:33 πŸ‘ 13 πŸ” 5 πŸ’¬ 1 πŸ“Œ 0

@ocortesazuero.bsky.social

14.12.2024 22:18 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Congratulations NoΓ©mie!πŸ₯³

23.11.2024 15:53 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Infectious Disease Modelling starter pack!

Suggestions are welcome!
go.bsky.app/86Ao1a5

10.11.2024 18:06 πŸ‘ 73 πŸ” 33 πŸ’¬ 13 πŸ“Œ 3
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Dynamics of measles immunity from birth and following vaccination - Nature Microbiology Serological data modelling informs on immune interference from maternal antibodies on measles vaccine responses in infants and children.

New work led by Wei Wang characterises the dynamics of measles immunity in infant&child cohorts in China. @hsalje.bsky.social www.nature.com/articles/s41...

14.05.2024 07:46 πŸ‘ 5 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Made it! Thanks to Steve Baker and Michael White for reading my thesis and for great discussions. And big thanks to @hsalje.bsky.social and the wonderful PDG team for making these years so great✨️

05.02.2024 11:09 πŸ‘ 6 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0

We’re hiring!! postdoc and research assistant (with potential for PhD) positions on mathematical modeling of infectious diseases at Cambridge (UK). Mainly of arboviruses including with longitudinal cohorts, disease mapping and models applied to multiplex serology in Africa. jobs.cam.ac.uk/job/44461/

19.12.2023 18:44 πŸ‘ 3 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0