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BrightFocus Foundation

@brightfocus

BrightFocus funds groundbreaking research in an urgent effort to discover cures for Alzheimer's disease, macular degeneration and glaucoma.

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Latest posts by BrightFocus Foundation @brightfocus

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Register for Zoom In On Dementia & Alzheimer's Learn about Alzheimer's and dementia treatments, risk reduction, and more during this free virtual discussion series with world-class expert research scientists.

On March 26, neurologist Dr. Sharon Cohen joins us to walk through the early signs of Alzheimer's, the conditions that can look like dementia but aren't, and how to have a productive conversation with your doctor.

Bring your questions. Register to join live: https://bit.ly/4qhsHsO

10.03.2026 00:14 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Alzheimerโ€™s Clinical Trials 2026: An Insiderโ€™s Look with Dr. Jeffrey Cummings YouTube video by BrightFocus Foundation

In 2025, 182 clinical trials evaluated 138 experimental drugs, reflecting real momentum in how scientists understand the biology, genetics, and biomarkers driving this disease.

Learn how that progress is translating into new ways to treat the disease.

๐Ÿ”ด WATCH LIVE TODAY: https://bit.ly/4aR3j7l

05.03.2026 15:46 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
The image is a promotional banner for "Glaucoma Chats," featuring Inas F. Aboobakar, MD. It includes text: "Discussing Glaucoma With Your Family," scheduled for Wednesday, March 11, 1 pm Eastern.

The image is a promotional banner for "Glaucoma Chats," featuring Inas F. Aboobakar, MD. It includes text: "Discussing Glaucoma With Your Family," scheduled for Wednesday, March 11, 1 pm Eastern.

Family history is one of the strongest risk factors for glaucoma.

Dr. Inas Aboobakar joins Glaucoma Chats to explain the role of genetics and family history in glaucoma, what and when to share with relatives, and how to encourage glaucoma eye exams.

Register: https://bit.ly/4u7l1Lh

04.03.2026 17:50 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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From disease-modifying therapies and oral pills to non-pharmacological options, the Alzheimerโ€™s treatment pipeline includes a wider range of approaches than ever before.

Read about whatโ€™s to come in 2026 and beyond: https://bit.ly/4aMpGcS.

27.02.2026 21:15 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Induced neurons derived from an Alzheimerโ€™s Disease patient. Green: Tuj, Red: NeuN.

Induced neurons derived from an Alzheimerโ€™s Disease patient. Green: Tuj, Red: NeuN.

Check out these stunning brain cells derived from a person with Alzheimerโ€™s disease.

โ€ข Green = Young
โ€ข Red = Mature

Dr. Josephy Herdy is using these stem cells to study how to stop brain inflammation in Alzheimerโ€™s disease.

Explore the research: https://bit.ly/3OqvJfz

26.02.2026 21:48 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Early-stage AMD often has no symptoms. By the time people notice vision changes, the disease may have already progressed.

That's why Paul, a stand-up comedian living with AMD, recommends comprehensive eye exams for everyone over 40, even if your vision seems fine. https://bit.ly/49L8K7n.

23.02.2026 18:13 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Understanding Your APOE Status: Genetics and Alzheimerโ€™s Risk YouTube video by BrightFocus Foundation

๐Ÿงฌ LIVE today at 1 p.m. ET: Dr. Eric M. Reiman joins us to discuss APOE4, genetic testing, and what it means for your Alzheimer's risk. We'll also discuss treatments, potential side effects, and clinical research opportunities. Your questions welcome! โ†˜๏ธ
https://www.youtube.com/live/XDRd-MRpDRY

19.02.2026 13:12 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Could we prevent Alzheimer's before memory loss begins?

Dr. Joshua Grill explains how researchers are exploring early treatment to slow or stop brain changes associated with Alzheimerโ€™s disease in people at higher risk.

Learn more about this promising area of research โžก๏ธ https://bit.ly/4k3QPMP.

15.02.2026 18:45 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Did you know? As many as 20 million U.S. adults aged 40 and older are living with some form of AMD.

Did you know? As many as 20 million U.S. adults aged 40 and older are living with some form of AMD.

Age-related macular degeneration (AMD) is a leading cause of vision loss, yet many people don't know they have it until irreversible vision loss occurs.

This #AMDAwarenessMonth, learn about the importance of regular eye exams, symptoms, risk factors & the latest research: https://bit.ly/4tzVDO1.

14.02.2026 20:06 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Image with text on a dark blue background. The text states: "FACT: Macular degeneration is the leading cause of vision loss in Americans 65 and older, causing irreversible damage that affects reading, driving, and recognizing faces."

Image with text on a dark blue background. The text states: "FACT: Macular degeneration is the leading cause of vision loss in Americans 65 and older, causing irreversible damage that affects reading, driving, and recognizing faces."

Reading a text message, recognizing a grandchild's face, navigating a familiar route: these ordinary acts rely on central vision. For nearly 20 million Americans, age-related macular degeneration puts all of that at risk.

But early detection offers hope. Learn more: https://bit.ly/4bD2WOG.

07.02.2026 19:49 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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BrightFocus Statement on Bipartisan Action to Protect Brain and Eye Research BrightFocus Foundation supports the bipartisan appropriations bill for fiscal year 2026, which provides critical federal funding for brain and eye research.

Breaking News: On Feb 3, Congress passed, and the President signed into law, the Fiscal Year 2026 appropriations bill providing critical federal funding for the NIH, protecting brain and eye research.

Read more. https://bit.ly/46qFBvV

04.02.2026 22:40 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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You wouldn't skip your other wellness appointmentsโ€”so why skip eye exams?

Cynthia reminds us that protecting our vision deserves the same priority we give to other aspects of self-care. Watch her story. โฌ‡๏ธ

Get the facts about glaucoma this #GlaucomaAwarenessMonth: www.stopglaucoma.org

28.01.2026 19:04 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Graphic for a Macular Chat titled: Can Retinal Implants Restore Vision?

Graphic for a Macular Chat titled: Can Retinal Implants Restore Vision?

TOMORROW: Learn how retinal prostheses are designed to restore visionโ€”not just slow its loss. Join us Wed, Jan 28 at 1 pm ET to explore the PRIMA implant and other breakthrough technologies currently in production.

Watch live: https://bit.ly/4qJtjXX

27.01.2026 17:55 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
This is an eye from a frog that was treated with CRISPR. Because CRISPR mutations that cause gene knockdown are random, we can sometimes get mosaicism, where some cells are healthy, and then the cells beside them are mutants. This is an excellent example of mosaicism, where some photoreceptors are healthy (left side), and others are mutants (right side).

This is an eye from a frog that was treated with CRISPR. Because CRISPR mutations that cause gene knockdown are random, we can sometimes get mosaicism, where some cells are healthy, and then the cells beside them are mutants. This is an excellent example of mosaicism, where some photoreceptors are healthy (left side), and others are mutants (right side).

CRISPR in action! The healthy cells (left) & disease-modified cells (right) create a 'mosaic' pattern, typical of gene editing.

Dr. Brittany Carr, BrightFocus Foundation Macular Degeneration Research grantee, is using this technique to build more precise disease models. https://bit.ly/3YKpMMC

22.01.2026 22:13 ๐Ÿ‘ 0 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Leqembi and Kisunla: Your Questions Answered Just three years ago, there were no FDA-approved treatments that targeted the underlying causes of Alzheimer's--only medications that modified symptoms. Today, two FDA-approved therapies--Leqembi (lecanemab) and Kisunla (donanemab)--clear amyloid protei...

For decades, Alzheimer's drugs only treated symptoms. That's changed. Two FDA-approved therapies now target amyloid protein in the brain. But what does that mean for people living with the disease?

Watch live: https://www.youtube.com/live/41AMx2fsdHM

21.01.2026 17:55 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Graphic for Zoom In on Dementia & Alzheimer's

Graphic for Zoom In on Dementia & Alzheimer's

Until recently, there were no Alzheimer's drugs that targeted the underlying causes of the disease. Now there are two.

On Jan 22, hear from a leading neurologist about Leqembi and Kisunlaโ€”how they work, who's eligible, and what you need to know.

Register: https://bit.ly/4qhsHsO

15.01.2026 21:11 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Glaucoma doesnโ€™t just affect older adults. It can affect anyone at any age.

Hillary explains why everyone, not just individuals with known risk factors, can benefit from regular eye exams to spot the earliest signs of glaucoma and other eye diseases.

Learn more at: www.stopglaucoma.org

14.01.2026 17:52 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Join tomorrow's Glaucoma Chat with Dr. Mehul Nagarsheth, who will break down how early diagnosis opens the door to modern, less invasive treatment options.

๐ŸŽง Listen live tomorrow, Jan. 14 at 1 p.m. ET: https://bit.ly/4qFdiBH

13.01.2026 18:52 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Alzheimers Policy Working Group The idea of losing your mental abilities, your independence, your sense of self, is hard to accept. No one wants to believe their memories are slipping away, or that they will become a burden to their loved ones. And so most people won't recognize the s...

Too many people see multiple specialists before receiving an Alzheimerโ€™s diagnosis, losing precious time.

BrightFocus Foundation supports the Alzheimerโ€™s Policy Working Groupโ€™s initiative to provide actionable policy guidance to accelerate diagnosis and improve care.

Read the report: alzpolicy.org

10.01.2026 00:00 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
BrightFocus Foundation Alzheimerโ€™s Disease Research grant recipient Joe Herdy, PhD

BrightFocus Foundation Alzheimerโ€™s Disease Research grant recipient Joe Herdy, PhD

โ€œI watched my grandfatherโ€™s sharp, witty mind fade away with dementia. That experience drives me to search for answers so other families donโ€™t feel the same helplessness.โ€
โ€” Joe Herdy, PhD, BrightFocus Foundation Alzheimer's Disease Research grant recipient.

Read more: https://bit.ly/4jAd4d1

08.01.2026 23:44 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Register for Glaucoma Chats

Glaucoma treatment has come a long way. Register for our Jan. 14 Glaucoma Chat where Dr. Mehul Nagarsheth will break down how diagnosing glaucoma earlier gives you access to modern, less invasive treatments.

๐Ÿ”— Register today and ask your questions live. https://bit.ly/3NyIYub

07.01.2026 21:11 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
An individual holding a tennis racket smiles while playing tennis, with a promotional message 'Why Young Brains Stay Sharp With Age'

An individual holding a tennis racket smiles while playing tennis, with a promotional message 'Why Young Brains Stay Sharp With Age'

๐Ÿง  Why do some people stay sharp at 85 while others struggle at 76?

The answer is "cognitive reserve," your brain's built-in resilience that can be strengthened through lifelong learning, physical activity, social connections, and proactive health management.

Learn more: https://bit.ly/49nPMCf

07.01.2026 00:10 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
whole mount merge iba1rbpms retina

whole mount merge iba1rbpms retina

The red cells are microgliaโ€”your eye's tiny defenders. ๐Ÿ›ก๏ธ These immune cells patrol the retina, protecting it from damage. Silvia Marinelli, PhD, a BrightFocus Foundation National Glaucoma Research grant recipient, is studying how we might harness them to fight vision loss.

๐Ÿ”ฌ https://bit.ly/4q6Ubkj

02.01.2026 20:46 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Explore What's New from BrightFocus's Alzheimer's Fast Track 2025 From BrightFocus Foundation

We're thrilled to announce that our Alzheimer's Fast Track 2025 workshop is being as the AARP Brain Health Action Collaborative Action of the Week!

By connecting early-career scientists with leading experts, weโ€™re igniting new ideas to advance Alzheimer's research: https://bit.ly/3MOcThQ.

23.12.2025 18:37 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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2025 Research Portfolios Spotlight Breakthrough Science BrightFocus is proudly supporting 186 cutting-edge research grants, fueling the global fight against Alzheimerโ€™s disease, macular degeneration, and glaucoma.

๐ŸŒ Smart science knows no borders!

BrightFocus Foundation is funding innovative research across 16 countries, supporting 186 projects that are advancing our understanding of Alzheimer's, macular degeneration, and glaucoma.

Explore our 2025 research portfolios: https://bit.ly/4sa1OrC

20.12.2025 20:13 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Graphic featuring a close-up of a researcher's hand holding a blood sample in a lab, with racks of test tubes in the background.

Graphic featuring a close-up of a researcher's hand holding a blood sample in a lab, with racks of test tubes in the background.

๐Ÿง  Researchers have identified a promising new class of blood biomarkers known as circular RNAs (circRNAs) for early Alzheimer's detection.

Read more : https://bit.ly/3N7zR3m

19.12.2025 20:59 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Fluorescence microscopy images of two cells, the left stained prominently in blue and green, and the right featuring multicolored speckles predominantly in blue, green, and red.

Fluorescence microscopy images of two cells, the left stained prominently in blue and green, and the right featuring multicolored speckles predominantly in blue, green, and red.

BrightFocus Foundation Alzheimerโ€™s Disease Research grant recipient Dr. Hongjun Fu grows โ€œmini-brainsโ€ to study why certain neurons are vulnerable in Alzheimerโ€™s & PSP.

These images show brain tissue at 60 days (left) and 120 days (right).

Read more about Dr. Fuโ€™s project: https://bit.ly/4s29wnt

18.12.2025 15:51 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Breaking News Dispatch: New Findings on GLP-1 Drugs and Alzheimer's, Novel Treatments in Development, and More Get the latest news from the 2025 Clinical Trials on Alzheimer's Disease (CTAD) conference.

The EVOKE trials found that semaglutide, the GLP-1 drug behind several popular diabetes and weight loss medications, did not meaningfully slow cognitive decline in people with Alzheimerโ€™s disease.

Explore this research and more news from #CTAD2025. https://bit.ly/48KgAxG

17.12.2025 00:09 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Did you know some people maintain sharp thinking skills even with Alzheimer's-related brain changes?

Building cognitive reserve through lifelong learning, social connections, and healthy lifestyle choices may help protect your brain.

Learn more: https://bit.ly/3MmMgAo

11.12.2025 15:53 ๐Ÿ‘ 3 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Breaking News Dispatch: New Findings on GLP-1 Drugs and Alzheimer's, Novel Treatments in Development, and More Get the latest news from the 2025 Clinical Trials on Alzheimer's Disease (CTAD) conference.

New study results indicate that lifestyle changes can protect aging brains. The U.S. POINTER study tested whether a structured, healthy lifestyle program could protect cognitive function in at-risk older adults. The answer is YES.

Explore this news and more from #CTAD2025: https://bit.ly/4pTAgoa

10.12.2025 18:27 ๐Ÿ‘ 2 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0