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David Lipshutz

@lipshutz

Studying neural computation • Assistant Professor of Neuroscience at Baylor College of Medicine • lipshutzlab.com

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11.11.2024
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Latest posts by David Lipshutz @lipshutz

Postdoctoral Associate - Specialist- Computational Cognition Postdoctoral Associate - Specialist- Computational Cognition

Help! We want to understand multi-task neural representations, but all we have is 24/7 spiking data from human patients in hippocampus and cortex, along with video, audio, speech, heart rate, and so much more!

If you can help, please apply to join the lab as a postdoc ☺️
jobs.bcm.edu/job/Postdoct...

13.01.2026 21:45 👍 32 🔁 9 💬 5 📌 0
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Our paper is out in @natneuro.nature.com!

www.nature.com/articles/s41...

We develop a geometric theory of how neural populations support generalization across many tasks.

@zuckermanbrain.bsky.social
@flatironinstitute.org
@kempnerinstitute.bsky.social

1/14

10.02.2026 15:56 👍 273 🔁 100 💬 7 📌 1
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Reduced rank regression for neural communication: a tutorial for neuroscientists Reduced rank regression (RRR) is a statistical method for finding a low-dimensional linear mapping between a set of high-dimensional inputs and outputs. In recent years, RRR has found numerous applica...

Bichan Wu (@bichanw.bsky.social) & I wrote a tutorial paper on Reduced Rank Regression (RRR) — the statistical method underlying "communication subspaces" from Semedo et al 2019 — aimed at neuroscientists.

arxiv.org/abs/2512.12467

17.12.2025 02:06 👍 110 🔁 37 💬 2 📌 1

At #NeurIPS2025!

🎉 Excited to present Conditionally Linear Dynamical Systems (CLDS). We leverage the dependence of neural dynamics on task covariates to yield an interpretable, flexible model of dynamics.

Come meet and check it out!
📍: Poster #2209, Hall C,D,E on Thu Dec 4, 11 am–2 pm, PST.

🧵/6

03.12.2025 17:44 👍 19 🔁 5 💬 1 📌 1

How prior experience biases new learning for generalization? new preprint is out:
1) behavioral and hippocampal generalization co-emerged in a novel context.
2) BTSP was involved in forming cross-context stable representations, as well as aligning novel neural dynamics to familiar subspace.

26.11.2025 16:27 👍 4 🔁 2 💬 1 📌 0
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Simons Foundation Now Accepting Applications for Workshop on Canonical Cortical Computations Simons Foundation Now Accepting Applications for Workshop on Canonical Cortical Computations on Simons Foundation

Inviting apps for a workshop to develop a project focused on a mechanistic understanding of canonical cortical computations at the circuit level. Deadline is 1/5/2026: https://www.simonsfoundation.org/simons-foundation-now-accepting-applications-for-workshop-on-canonical-cortical-computations

24.11.2025 18:47 👍 14 🔁 9 💬 1 📌 1
Doctoral studies in Computational/Theoretical Neuroscience at NYU

Looking for a PhD program where you can study computational neuroscience? NYU has a fantastic array of researchers covering the field:

groups.google.com/g/systems-ne...

25.10.2025 14:19 👍 49 🔁 18 💬 2 📌 1
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Applying to do a postdoc or PhD in theoretical ML or neuroscience this year? Consider joining my group (starting next Fall) at UT Austin!
POD Postdoc: oden.utexas.edu/programs-and... CSEM PhD: oden.utexas.edu/academics/pr...

23.10.2025 21:36 👍 33 🔁 11 💬 1 📌 0
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📣 WTI is hiring faculty positions! Are you interested in advancing our understanding of the brain + how it gives rise to cognition?

Two calls are open:

Open-rank search, Neurocomputation, deadline: 12.1.25
Senior search, Neurodevelopment, rolling review

🔗 wti.yale.edu/opportunities

#KnowTogether

03.10.2025 16:43 👍 9 🔁 14 💬 1 📌 2
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Mirror manifolds: partially overlapping neural subspaces for speaking and listening Participants in conversations need to associate words their speakers but also retain those words general meanings. For example, someone talking about their hand is not referring to the other speakers ...

New manuscript from the lab!

"Mirror manifolds: partially overlapping neural subspaces for speaking and listening"

Led by superstar grad student Anilu Chavez (not on Bluesky)!

www.biorxiv.org/content/10.1...

22.09.2025 14:15 👍 66 🔁 20 💬 2 📌 2

Very cool work showing how hippocampal representations could span space, and associative/episodic memories. Thanks for the presentation today Sarthak!

10.09.2025 20:48 👍 8 🔁 1 💬 0 📌 0
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Sinclair Lab The Learning & Behavior Change Lab at Rice University, directed by Dr. Sinclair

🌟 Excited to share that I'm recruiting PhD students in Psychology for my new lab at Rice University this cycle (Signal boost appreciated!)

To learn more, check out the Learning & Behavior Change Lab website:
www.sinclairlab-rice.com

Applications are due Dec 1st: psychology.rice.edu/graduate/pro...

08.09.2025 15:45 👍 63 🔁 48 💬 2 📌 1
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Frontiers | Summary statistics of learning link changing neural representations to behavior How can we make sense of large-scale recordings of neural activity across learning? Theories of neural network learning with their origins in statistical phy...

Since I'm back on BlueSky - with @frostedblakess.bsky.social and @cpehlevan.bsky.social we wrote a brief perspective on how ideas about summary statistics from the statistical physics of learning could potentially help inform neural data analysis... (1/2)

04.09.2025 18:30 👍 34 🔁 10 💬 1 📌 0

Join us at #NeurIPS2025 for our Data on the Brain & Mind workshop! We aim to connect machine learning researchers and neuroscientists/cognitive scientists, with a focus on emerging datasets.

More info: data-brain-mind.github.io

05.08.2025 00:21 👍 17 🔁 7 💬 0 📌 0
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Fast efficient coding and sensory adaptation in gain-adaptive recurrent networks As the statistics of sensory environments often change, neural sensory systems must adapt to maintain useful representations. Efficient coding prescribes that neuronal tuning curves should be optimize...

Efficient coding theories often implicitly or explicitly assume slow changes in tuning (e.g., through synaptic plasticity). Arthur Prat-Carrabin has collected psychophysical data showing that it can be fast, and this can be explained by a gain-adaptive RNN:
www.biorxiv.org/content/10.1...

17.07.2025 15:54 👍 45 🔁 10 💬 0 📌 0
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In-context denoising with one-layer transformers: connections between attention and associative memory retrieval We introduce in-context denoising, a task that refines the connection between attention-based architectures and dense associative memory (DAM) networks, also known as modern Hopfield networks. Using a...

At #ICML2025, presenting work done at @flatironinstitute.org w Matt Smart and @albertobietti.bsky.social on in-context denoising (arxiv.org/abs/2502.05164). Come to Matt’s oral, Thursday, 4:15-4:30 PM, West Ballroom A, and see us right after at poster #E-3207, 4:30-7:00 PM, East Exhibition Hall A-B.

16.07.2025 18:37 👍 5 🔁 3 💬 0 📌 0
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Announcing the new "Sensorimotor AI" Journal Club — please share/repost!

w/ Kaylene Stocking, Tommaso Salvatori, and @elisennesh.bsky.social

Sign up link: forms.gle/o5DXD4WMdhTg...

More details below 🧵[1/5]

🧠🤖🧠📈

09.07.2025 22:31 👍 24 🔁 12 💬 1 📌 0
JOV Special Issue - Choose your stimuli wisely: Advances in stimulus synthesis and selection | JOV | ARVO Journals

Submissions now accepted for a special issue of the Journal of Vision:

Choose your stimuli wisely: Advances in stimulus synthesis and selection

Submission deadline: Dec 12, 2025
Futher details: jov.arvojournals.org/ss/synthetic...

18.06.2025 20:47 👍 16 🔁 13 💬 0 📌 2
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What is the probability of an image? What do the highest and lowest probability images look like? Do natural images lie on a low-dimensional manifold?
In a new preprint with Zahra Kadkhodaie and @eerosim.bsky.social, we develop a novel energy-based model in order to answer these questions: 🧵

06.06.2025 22:11 👍 71 🔁 23 💬 1 📌 2
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1/6 Why does the brain maintain such precise excitatory-inhibitory balance?
Our new preprint explores a provocative idea: Small, targeted deviations from this balance may serve a purpose: to encode local error signals for learning.
www.biorxiv.org/content/10.1...
led by @jrbch.bsky.social

27.05.2025 07:49 👍 181 🔁 57 💬 5 📌 3

New #NeuroAI #compneurosky preprint! To better understand how target-directed learning works in the brain, we sought to engineer an artificial neural network capable of solving complex image classification tasks that comprises only experimentally-supported biological building blocks. (1/15)

27.05.2025 18:40 👍 49 🔁 19 💬 1 📌 1
VSS SymposiaSymposia – Vision Sciences Society

Super excited for our #VSS2025 symposium tomorrow, "Model-optimized stimuli: more than just pretty pictures".
Join us to talk about designing and using synthetic stimuli for testing properties of visual perception!

May 16th @ 1-3PM in Talk Room #2

More info: www.visionsciences.org/symposia/?sy...

15.05.2025 20:31 👍 25 🔁 6 💬 1 📌 0
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🧠🤖 Computational Neuroscience summer school IMBIZO in Cape Town is open for applications again!
 
💻🧬 3 weeks of intense coursework & projects with support from expert tutors and faculty
 
📈Apply until July 1st!

🔗https://imbizo.africa/

08.05.2025 08:19 👍 35 🔁 29 💬 1 📌 4

Congrats!!!

26.04.2025 01:58 👍 1 🔁 0 💬 1 📌 0

Exciting news!! I’m joining the tenure-track faculty at University of Colorado Boulder this fall as an Assistant Professor of Psychology & Neuroscience!

The Sosa Lab will study how memory is shaped by cognitive and physiological demands, including during pregnancy and the postpartum period. 🧵

25.04.2025 17:17 👍 350 🔁 36 💬 53 📌 2
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Discriminating image representations with principal distortions Image representations (artificial or biological) are often compared in terms of their global geometric structure; however, representations with similar global structure can have strikingly...

We are presenting our work “Discriminating image representations with principal distortions” at #ICLR2025 today (4/24) at 3pm! If you are interested in comparing model representations with other models or human perception, stop by poster #63. Highlights in 🧵
openreview.net/forum?id=ugX...

24.04.2025 05:12 👍 39 🔁 13 💬 1 📌 0
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Symposium at the annual VSS meeting on generative models for vision science

23.04.2025 13:00 👍 5 🔁 3 💬 1 📌 0
ICLR 2025 Comparing noisy neural population dynamics using optimal transport distances OralICLR 2025

Excited to announce that our paper on "Comparing noisy neural population dynamics using optimal transport distances" has been selected for an oral presentation in #ICLR2025 (1.8% top papers). Check the thread for paper details (0/n).

Presentation info: iclr.cc/virtual/2025....

22.04.2025 18:06 👍 23 🔁 7 💬 1 📌 0
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Novel color via stimulation of individual photoreceptors at population scale Image display by cell-by-cell retina stimulation, enabling colors impossible to see under natural viewing.

This paper is the result of >20 yrs of hard work by talented students, postdocs and collaborators, but none more than my co-author Ren Ng and his team in EECS.
1/n
Novel color via stimulation of individual photoreceptors at population scale | Science Advances www.science.org/doi/10.1126/...

20.04.2025 19:39 👍 92 🔁 36 💬 1 📌 5