Arnab Ray Chaudhuri

Thanks Aura!

⏰ Only 1 week left!
Registration for #DRRSC26 closes soon - don’t miss out on being part of this exciting conference.
📅 Deadline: 25 November 2025
Click here to Register: bit.ly/49oHUCi
#FusionStructuralMolBio #FusionDNA

Thanks Nadeem!

Thanks Andy!

Thanks Marcus!

Thanks a lot Sofia!

Thanks a lot Francesca!

Thanks a lot Marcel!

Human RPA is an essential telomerase processivity factor for maintaining telomeres Telomerase counteracts telomere shortening by repeatedly adding DNA repeats to chromosome ends. We identified the replication protein A (RPA) heterotrimer as a telomerase processivity factor critical ...

Our paper in Science is out! @souravagrawal.bsky.social, @rlynn.bsky.social, @susvirkar.bsky.social, and the rest of the team show human RPA is a telomerase processivity factor essential for telomere maintenance. This reshapes our thinking about telomerase regulation. www.science.org/doi/10.1126/...

We show that anti-recombinase FIGNL1 removes RAD51 in BRCA2 deficient cells causing homologous recombination defects and loss of FIGNL1 restores functional recombination in these cells. More on the mechanism in the manuscript.

A tour de force by Raviprasad Kuthethur and amazing collaborations from @cejkalab.bsky.social ,Shyam Sharan and Krishna Mohan Poluri labs. Thanks a lot to Safa Nasrin, Satheesh Kumar Sengodan, Stefan Braunshier, Carmen Fonseca , Nupur Nagar, Ananya Acharya for putting it all together.

FIGNL1 inhibits homologous recombination in BRCA2 deficient cells by dissociating RAD51 filaments Homologous recombination (HR) deficiency upon Breast Cancer Gene 2 (BRCA2) loss arises from defects in the formation of RAD51 nucleoprotein filaments. We demonstrate that loss of the anti-recombinase ...

Want to know how homologous recombination defects are caused upon loss of BRCA2? Check out our recent efforts in uncovering this phenomenon just out in Science!
www.science.org/doi/10.1126/...

@raychaudhurilab.bsky.social we are looking forward to your presentation at the #DRRSC26 🌟
Please share this with your followers to let them know the Early bird and Talk submission deadline is fast approaching - Tuesday 26th August 2025 ⏳
🔗To register click here: bit.ly/4o3w0Cz

Please help us spread the word by resharing: @loizoulab.bsky.social @hopfnerlab.bsky.social @lapassmore.bsky.social @raychaudhurilab.bsky.social
@hw1o9.bsky.social @westlabcrick.bsky.social @rswilliamslab.bsky.social @gwuite.bsky.social @dijiang319.bsky.social

Join the first Keystone conference dedicated to DNA replication gaps and cancer! Send an abstract to be selected for a talk.

www.keystonesymposia.org/conferences/...

What an exciting day for the lab at the Dutch Chromatin Meeting! Congrats to Ashutosh (a.k.a Vincent 😉)for winning the poster prize on 3D reorganization of stressed forks & Joanna for her fantastic talk on phase separation during replication stress. Proud of you guys! 🤩

Congrats Francesca and team!

Being haiku-ed is an honor! You were so fast, too 🤩