Biofabrication Würzburg

🚨Our hydrogel-based tubular airway-on-chip (“airway-on-tube”) is now published in Advanced Materials!
🔗 advanced.onlinelibrary.wiley.com/doi/10.1002/...
Thanks to collaborators in Cambridge & Würzburg and to DFG for funding my independent postdoc fellowship.

"From Fiber Architecture to Functional Attachment: A Clinically Relevant, Mechanically Tunable #Cardiac Patch" is now published in Advanced Materials, huge collaboration from the EU "Brav3" project:
advanced.onlinelibrary.wiley.com/doi/10.1002/...

We are happy to share with you this new publication:
Hydrogel-Based Airway-on-Tube With Perfusable Endothelial Lumen and Outward Epithelialization
@bartolfkopp.bsky.social provided tubular MEW scaffolds as support for a hydrogel based lung-on-a-chip 🫁
advanced.onlinelibrary.wiley.com/doi/10.1002/...

We just published our work on light-free cross-linking of #polyoxazoline -based #microgels for a safe #cellEncapsulation.
Congratulations to projects A06 and A02 from our CRC #TRR225
onlinelibrary.wiley.com/doi/10.1002/...

Check this new #biomaterial for #MeltElectrowriting out!
💥
Poly(Alkylene Terephthalate)s #PAT is a shape memory polymer with tuneable thermo mechanical properties,
collaboration with the University of Ghent
advanced.onlinelibrary.wiley.com/doi/10.1002/...

A glimpse in our new format: #ScientificBrunch!

With the group expanding over three buildings we want to mix the groups up, chat and catch up with FMZ scientists of al levels over coffee and pastry!
Lay the groundwork for #communitybuilding, #collaboration and #exchange of ideas and knowledge #FMZ

Gradients are everywhere! especially in our #tissues and organs, so when talking about #hierarchy and #biomimicry it is important that our technologies are able to reproduce such structures.
analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...

Biocompatibility of Hydrogels for Glomerular 3D Co‐Culture: A Comparative Analysis GelAGE and recombinant spider silk hydrogels are evaluated for glomerular 3D co-culture. GelAGE combines ease of handling with excellent biocompatibility and viscoelasticity, making it a promising sc...

I was happy to contribute to our new paper from #CRCTRR225 project C06
This work encompasses the collaborative spirit of the consortium as 5 projects were involved providing different bioinks to test for compatibility with glomerular spheroids for 3D cultures
onlinelibrary.wiley.com/doi/10.1002/...

Magnesium Phosphate Minerals and Cements as Bone Substitute Materials When bone defects surpass a critical threshold in size, they typically necessitate intervention through either autologous bone grafting or the use of …

What a better way to start the year with a brand new publication!
Check this new review on "Magnesium Phosphate Minerals and Cements as Bone Substitute Materials" now available on Acta Biomaterialia.
www.sciencedirect.com/science/arti...

We started the year with an amazing time at the Alpine Winter School of #Biofabrication.
Thanks for the organization to Aleksandr Ovsianikov and Julia Fernández-Pérez, we had the opportunity to listen to and engage in discussions with leading voices in our field from all over the world.

new publication out before the end of the year: the synthesis and application of a star-shaped poly(2-methyloxazoline) functionalized with boronic acid derivatives, designed to form stable #hydrogels in the presence of poly(vinyl alcohol) under physiological conditions.
pubs.acs.org/doi/full/10....

The whole FMZ #Biofabrication wishes everyone a happy and peaceful holiday time!
2025 was a successful year for us and we are thankful for all our employees and students bringing their enthusiasm and passion for science.
Looking forward to what next year will bring with a lot of new beginnings!

Christmas 🎄 is already in the air!
We teamed up with all other groups from the dentistry clinic 🦷 and set up our booth at the local craft bazaar ✂️ to raise money for a good cause ✨
We are had a very successful evening of coming together with all coworkers of the clinic for something important.

Giving It a Twist: One‐Step Fabrication of Aligned Biomimetic Yarn Scaffolds via Rotational Melt Electrofibrillation Due to its multifunctionality, replicating the fibrillar and supramolecular architecture of Collagen I is gaining increasing priority in regenerative medicine. Using rotational Melt Electrofibrillati...

We have a new publication!
We gave melt #electrofibrillation #MEW a twist for #tendon #TissueEngineering and adaptable stretchable #collagen mimicking structures. Check the cool pictures and read the publication on Advanced Healthcare #Materials:
advanced.onlinelibrary.wiley.com/doi/10.1002/...

Are you a student just starting in the field of #bioprinting or #biofabrication? this review is for you!
Check our new review about the current status of bioprinting organs from the perspective of phd students, out now on Advanced Healthcare Materials
advanced.onlinelibrary.wiley.com/doi/10.1002/...

Bioprinting organs: science or fiction?
Finally online a broad and comprehensive snap shot of where we're at but also a glimpse and bet into the future with the particular perspective of phd students working on it every day.

Check our latest publication about fabricating fibrillar bundle additives for muscle #bioprinting
advanced.onlinelibrary.wiley.com/doi/10.1002/...

Here we are in Dresden for the annual #DGBM25 Conference!
Come find us around at the poster session
our team is showing their latest resuls on #biofabrication, #bioprinting and #bone cements
tomorrow at 11 nathaly chicaiza will have her talk on #vasculature bioprinting

Want to know more about #antibiotic-loaded mineral #bone #cements?

check out our new publication in Acta Biomaterialia:
"Interaction mechanisms between antibiotics and calcium phosphate cements as pharmacologically active bone graft substitutes"
www.sciencedirect.com/science/arti...

Clinically applicable antibiotic modification of ready-to-use calcium phosphate cement pastes - Journal of Orthopaedic Surgery and Research Background Ready-to-use non-aqueous cement pastes consist of an organic, water-miscible liquid phase in which cement powder is dispersed. While the modification of classical aqueous powder/liquid cement pastes with antibiotics has been extensively investigated, only a few studies previously published aimed at drug modification of premixed cement pastes. Methods A simple method for modifying such ready-to-use pastes with the model antibiotic vancomycin is described. It was demonstrated that mixing the cement paste and vancomycin solution multiple times using an adapter between two syringes resulted in macroscopically homogeneous pastes. The antibiotic-loaded cements were thoroughly characterized with regard to their physicochemical properties and their drug release profile. Results Drug modification with vancomycin had no adverse effects on cement properties in terms of mechanical performance, phase composition, porosity and pore size distribution. Drug release from ready-to-use pastes exhibited a lower initial burst release of 14.5% compared to 47.9% for aqueous powder/liquid cement pastes after 24 h. At later time points, the initial exponential release kinetics slowed down due to both a decreased concentration gradient and structural changes of the cement matrix during setting. This resulted in sustained release of the antibiotic for more than 30 days. The released vancomycin maintained high antimicrobial activity against S. aureus with inhibition zones of 5.4–6.8 mm in an agar diffusion test. Conclusion The results demonstrated that modification of ready-to-use cement pastes with vancomycin is a potential candidate for clinical application, as it preserves both the material’s properties and the antibiotic’s activity.

New publication from our Bone Cements group:
Clinically applicable antibiotic modification of ready-to-use calcium phosphate cement pastes
link.springer.com/article/10.1...

New publication in collaboration with Dr. Torsten Blunk's lab:
congrats @camillamussoni.bsky.social and colleagues
advanced.onlinelibrary.wiley.com/doi/10.1002/...

Later this week we will be in Dresden for the #DGBM German Society for #Biomaterials Annual Conference.
Here all our contributions you can look forward to

Annual Betriebsausflug on the way in Marktbreit,
the fall landscape nicely framed our excursion!

MEW/PVA‐MA Hydrogel Vascular Grafts: Enhancing Hemocompatibility and Endothelialization A biomimetic vascular graft combining biofunctionalized PVA-MA hydrogels with a MEW scaffold is developed for small-diameter applications. Gel-MA and Hep-MA incorporation enhances endothelialization ...

New publication!
A novel biomimetic approach by combining PVA-MA-based hydrogels with #MEW scaffolds, creating a customizable #vasculargraft where the #hydrogels offer potential as ECM for cell attachment while the MEW scaffolds provide reinforcement
advanced.onlinelibrary.wiley.com/doi/10.1002/...

here the summary of our experience in Warsaw at #ISBF #Biofabrication2025 with the CRC TRR225 Biofabrication, so much fun!

#biofabrication #biofabrication #isbf #awards #biofabrication2025 #sciencecommunication #iop | Biofabrication 2025 🖼️ IOP Best Poster Awards 2025 🖼️ We are pleased to announce the winners of the IOP Best Poster Awards presented at the International Society for Biofabrication 2025 Conference. These awards honor pos...

love that ISBF notice
www.linkedin.com/posts/biofab...

Back from #ISBFWarsaw2025, what a fantastic time I had this week
I couldn't imagine a better way to conclude my phd journey in the #Biofabrication family than this.
I am grateful to the ISBF for granting me the IOP Best Poster Award at #Biofabrication2025.

We had an absolutely amazing time at #ISBFWarsaw2025!
The #Biofabrication2025 conference always feels like a family reunion, it was good to catch up with friends and learn about the latest results and share what we've been up to!
It was truly inspiring to see the community come together once more.

another busy day over in Warsaw for #Biofabrication2025.
here the summary of our fantastic day of talks 📊 and posters 📃
#ISBFWarsaw2025

a new day of talks and poster, we already had 2 rapid fire talks early this morning, check out prof. Groll and prof. Jüngst's talks and Nathaly Chicaiza's poster today!
#Biofabrication2025 #ISBFWarsaw2025