Rollenske lab

Efficient Expression and Purification of Recombinant Mouse Dimeric IgA Immunoglobulin (Ig) A is the main antibody isotype found on mucosal surfaces in mammals, where it is predominantly present as a dimer. Here we provide an easy, scalable, efficient, and broadly applic...

We are very happy about the first publication from the Rollenske lab! Remember the last time you wanted to efficiently produce and purify recombinant dimeric mouse IgA, but you didn't know how? Here you can finally find the answer: onlinelibrary.wiley.com/doi/10.1002/...

Expression Cloning of Antibodies from Single Human B Cells - PubMed The majority of lymphomas originate from B cells at the germinal center stage. Preferential selection of B-cell clones by a limited set of antigens has been suggested to drive lymphoma development. Wh...

We are IgA enthusiasts, but sometimes we are unfaithful: Together with our colleagues, we have updated the "IgG cloning and production from single B cells"-pipeline incl. the game-changing gene synthesis, DNA assembly and small-scale transfection steps. pubmed.ncbi.nlm.nih.gov/39424722/

Mucosal stargazing! It was a pleasure to write a Preview for the new Cell Host & Microbe publication of Bana Jabri's team on how IgA can control intestinal virus populations. @cp-cellhostmicrobe.bsky.social

Preview: authors.elsevier.com/a/1kvDC6t8JE...

Paper: www.cell.com/cell-host-mi...