Mustafa Sahin

🗣️Non-federal funding alert!!! Aligning Research to Impact Autism (ARIA) has a new RFA to join their IMPACT Network, a clinical-translational research effort to accelerate care for people across the spectrum by enabling rapid therapeutic development. Up to $15 million over 5 years.

bit.ly/3YRYMv3

Kari Rosbeck making opening remarks at the inspirational TSC Alliance Regional Conference in Boston

Phenotypic rescue via mTOR inhibition in neuron-specific Pten knockout mice reveals AKT and mTORC1-site specific changes - Molecular Psychiatry Molecular Psychiatry - Phenotypic rescue via mTOR inhibition in neuron-specific Pten knockout mice reveals AKT and mTORC1-site specific changes

Excited to share a new paper from our lab out this week in Molecular Psychiatry on an mTORopathy, PTEN Hamartoma Tumor Syndrome.

www.nature.com/articles/s41...

Macrophages protect against sensory axon loss in peripheral neuropathy - Nature A study in a mouse model of obesity and prediabetes demonstrates that recruitment of macrophages to nerves has a protective role in diet-induced peripheral neuropathy.

Research from the lab of Clifford Woolf at Boston Children's finds that, in a mouse model of type 2 diabetes, immune cells flood into peripheral nerves. This insight could lead to strategies to prevent peripheral neuropathy in diabetes.

www.nature.com/articles/s41...

A new review of protein homeostasis in neurodevelopmental disorders led by Dr. Kellen Winden at Boston Children's Hospital and Juan Ruiz who is now attending MD-PhD program at Yale School of Medicine

authors.elsevier.com/a/1kAvF3Q9h2...