Friendly reminder from AI-Lindsey: ChatGPT isn’t ‘smart’, it’s obedient.
If your prompt is fuzzy, your result will be… creative.
@lindseyvanhaute
Next generation sequencing geek and mitochondria lover https://www.nextgenseqanalysis.com Check out my YouTube channel: https://www.youtube.com/@SimpleScienceLVH #RNA,#DNA,#mitochondria,#NGS #RNAseq,#Genomics,#bioinformatics,#equality
Friendly reminder from AI-Lindsey: ChatGPT isn’t ‘smart’, it’s obedient.
If your prompt is fuzzy, your result will be… creative.
Student mental health is in crisis — here’s how to help
www.nature.com/articles/d41...
What factors contribute the most to PhD satisfaction? Stipends that are more than just a living wage? Manageable hours? A supportive team? These all matter, and are often in short supply. Another factor often overlooked is supportive supervision.
www.nature.com/articles/d41...
Higher education is being reshaped by powerful forces — from AI to mental health to decolonization. Six scholars offer fresh ideas for how universities can truly evolve.
www.nature.com/articles/d41...
Can I join please?
The rise in applications indicates a “huge increase in the amount and cost of work for academics completing these applications”. “[Researchers] must be spending less time either teaching or doing research, and spending more time on writing these grants”.
www.nature.com/articles/d41...
1 AUG
P-hacking
Removing outliers, using alternative statistical methods and running extra experiments are some methods that could be used to change the P-value. Be careful not to fall in this trap! Stay sceptical! Null results are a normal part of science.
www.nature.com/articles/d41...
It was fantastic to have @labliston.bsky.social give a talk at the @mrc-mbu.bsky.social on building a positive research culture. Valuable for all investigators/group leaders regardless of career stage, check out the resources below:
listonlab.uk/careers/
The temptation to create beautify images can be a slippery slope.
www.nature.com/articles/d41...
Stem cells were initially touted as a cure-all, but aside from a few anecdotal studies, this has not been proven true. Is it finally going to happen?
www.nature.com/articles/d41...
Clinically translatable mitochondrial #GeneTherapy in muscle using tandem mtZFN architecture.
By P. Nash, @mitogene.bsky.social & colleagues @mrc-mbu.bsky.social
🗞️ doi.org/10.1038/s443...
Read also related N&V by A. Ghifari & M. Ott 👉 doi.org/10.1038/s443...
Congratulations, Pavel!
Proud to have been involved in this project.
Reposting since it's been a while since I posted this, and new MBU members might have joined.
Mitochondria differ in type and density in different parts of the brain. For example, the evolutionarily oldest brain regions have a lower density of mitochondria than newer regions.
www.nature.com/articles/d41...
Shared first authorship, but who gets to be first? According to this study, there is no disadvantage to sharing credit.
Weakness of the study: The test name was a gender-neutral European name. Can someone please repeat this study with female/non-European names?
www.nature.com/articles/d41...
In-cell architecture of the mitochondrial respiratory chain | Science www.science.org/doi/10.1126/...
“These findings will need to be confirmed in vivo.“
Animal research can be extremely valuable, but isn't it time to encourage novel alternative non-animal models if they are available? Shouldn't funders encourage research to establish such alternative models more?
www.nature.com/articles/d41...
It is often said that the first responsibility of any government is the safety and protection of its people. Vaccines save lives, and casting doubt on their safety could have dangerous and far-reaching consequences.
www.nature.com/articles/d41...
Neural pathways in addiction: The hypothesized main neural circuits in human addictive behaviors are shown. The “feels better” path includes positive and negative reinforcement experiences and involves the ventral striatum (nucleus accumbens), and the dorsal striatum in later stages. The “must do” path includes primarily compulsive behaviors, involving the dorsal striatum (putamen and caudate nucleus). The “stop now” self-control process mainly involves the dorsolateral prefrontal cortex.
Can internet use become addictive?
A #SciencePerspective discusses the addictive potential of the #internet and how it can be best conceptualized and evaluated. scim.ag/3R5Npv1 #BrainAwarenessWeek
Conference alert: Machines acting on DNA and RNA
Madrid, May 28-30
Abstract deadline: April 24
Organised by @cniostopcancer.bsky.social. Come to share your research with experts in the molecular mechanisms of DNA & RNA machines. See the list of speakers below.
Please repost.
Thought that only purine nucleotides could inhibit mitochondrial thermogenesis in brown adipose tissue? Edmund Kunji and coworkers @mitocarriers.bsky.social @mrc-mbu.bsky.social show that pyrimidines bind and inhibit UCP1 in similar manner
www.embopress.org/doi/full/10....
Today is World Kidney Day. Are you sure your kidneys are OK? Do the quick test in the link and read about the risks.
www.worldkidneyday.org/2025-campaign/
Alcohol raises the risk of at least seven types of cancer, including breast, liver, and esophageal cancer. Yet, many drinkers remain unaware.
Is there truly a “safe” amount of alcohol? Would a cancer warning label be helpful?
htps://www.nature.com/articles/d41586-025-00729-5
An illustration of a man pushing away a black mass. Hedline is: Science used to be my safe space. But when I spiraled into depression, I quit my Ph.D.
"I had spent half my life working toward my dream of being a scientist. It had given me a sense of purpose. But now it dawned on me that, for the sake of my health, I was going to have to let that dream go."
This week's #ScienceWorkingLife. scim.ag/4bCwyth