Harrison York's Avatar

Harrison York

@harrisonyork

Post-Doc at NeuroCyto lab, Aix-Marseille Université | Cell-biologist and Microscopist keeping an eye out for the selcouth

92
Followers
120
Following
7
Posts
07.06.2025
Joined
Posts Following

Latest posts by Harrison York @harrisonyork

Video thumbnail

Excited to share our work enabling imaging across scales, from molecular assemblies at a few hundred nanometers to living organisms and tissues at millimeter scale, with minutes time resolution.
www.biorxiv.org/content/10.6...

26.02.2026 12:26 👍 1 🔁 2 💬 0 📌 0
Video thumbnail

Great news! @mariaingaramo.bsky.social 's company (Nonfiction Labs) made a remote-controlled antibody.

Its binding turns on and off with a magnet.

This is a HUGE step towards our dream of magnetically controlled drugs. Imagine a cancer drug that ONLY attacks the tumor, not the rest of your body.

13.01.2026 04:57 👍 70 🔁 19 💬 2 📌 5
Preview
Direct labeling of microtubule turnover reveals in-lattice repair and stabilization patterns in developing neurons The microtubule cytoskeleton is the backbone of neuronal morphogenesis, driving the development of the dendrites and axon, and supporting trafficking to distant compartments. How neuronal microtubules...

🚨The Neurocyto lab is branching out in our latest preprint! We used tubulin microinjection to directly visualize microtubule turnover in developing hippocampal neurons, demonstrating the presence of in-lattice repair and a selective stabilization in the nascent axon. Check below, or read on 🧵 1/9

12.01.2026 19:14 👍 102 🔁 31 💬 4 📌 2

At the end of the day all experiments are hazy, our job as scientists is to synthesise incomplete data and peer beyond the veil, not just do every control (possible or not) that a chatbot tells us to!

07.11.2025 16:58 👍 1 🔁 0 💬 0 📌 0

Jokes aside I think this belies a concerning problem with the rise of AI tools in science. Reading scientific literature is not just about parsing the logic of the writing, it is also about assessing the quality of the data to evaluate the findings, to understand the context of the experiments

07.11.2025 16:57 👍 1 🔁 0 💬 1 📌 0
Post image

Testing out the new hyped AI peer review tool (@qedscience.bsky.social) on one of my old papers and saw many of the errors people are posting about online, but this comment made me laugh! Thank you LLM for blindly trusting my movies are amazing even if you have not seen them

07.11.2025 16:57 👍 2 🔁 1 💬 1 📌 0
How to apply for an EMBO Postdoctoral Fellowship: Tips from the Committee
How to apply for an EMBO Postdoctoral Fellowship: Tips from the Committee YouTube video by EMBO - excellence in life sciences

Want to apply for an EMBO Postdoctoral #Fellowship? 🧪

Here are tips from the EMBO Fellowship Committee:
www.youtube.com/watch?v=xY7c...
#LifeSciences #grant #funding

07.10.2025 14:10 👍 7 🔁 4 💬 0 📌 1
Preview
Research engineer in Bioimage Analysis for the researchers of the inIdEx FORMULA Hi all We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks? The position is in the Instit...

Job alert!

We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks?

See also on the forum:
forum.image.sc/t/research-e...

07.10.2025 12:39 👍 62 🔁 80 💬 2 📌 8
Post image

Our new preprint is up! This is the main postdoc work of @wiesner-t.bsky.social focusing on exocytosis along the axon shaft and its regulation by the sub membrane actin-spectrin scaffold: www.biorxiv.org/content/10.1...
Read the thread below for a summary of our findings 🧵1/11

17.09.2025 14:54 👍 131 🔁 48 💬 6 📌 5
Post image

New NeuroCyto preprint about to drop! @wiesner-t.bsky.social 😎⏳

16.09.2025 16:48 👍 39 🔁 6 💬 4 📌 1
Video thumbnail

Despite their high rigidity, microtubules (MTs) dynamically bend and buckle in cells. MT-self repair is inherent to their metastable nature, but it remains unclear whether just inherent repair mechanisms are sufficient to maintain MT integrity🧵 (1/9)
www.biorxiv.org/content/10.1...

14.09.2025 09:53 👍 43 🔁 16 💬 1 📌 4
Preview
Tau accelerates tubulin exchange in the microtubule lattice - Nature Physics Beyond its known role in stabilizing microtubules, it is now shown that tau protein actively promotes lattice defect repair by enhancing tubulin turnover at topological defects.

Excited to share that my paper on Tau–Microtubule interactions is now published in Nature Physics!🎉

Our work shows that tau goes beyond stabilizing microtubules—it also promotes the removal of defects in the microtubule lattice.

www.nature.com/articles/s41...

09.09.2025 11:56 👍 30 🔁 12 💬 1 📌 2
Preview
Conserved nucleocytoplasmic density homeostasis drives cellular organization across eukaryotes Nature Communications - Cells can regulate their mass density. Here, the authors demonstrate how eukaryotes establish and maintain a lower density in the nucleus than in the cytoplasm via pressure...

FINALLY! Challenging to publish but we believe it is an important discovery: rdcu.be/eATFz

💚 Thanks to the team ‪@biswashere.bsky.social‬, Omar Muñoz, ✨Q✨ C. Hoege, B. Lorton, R. Nikolay ‪@matthewkraushar.bsky.social‬ @dshechter.bsky.social @gucklab.bsky.social @vasilyzaburdaev.bsky.social‬ 💚

15.08.2025 11:54 👍 55 🔁 25 💬 1 📌 5
FlyBase:Contribute to FlyBase - FlyBase Wiki

FlyBase needs your help! We ask that European labs continue to contribute to Cambridge, UK FlyBase, whereas US and other non-European labs can contribute to US FlyBase. For more information and how to donate: wiki.flybase.org/wiki/FlyBase...

15.08.2025 12:45 👍 130 🔁 159 💬 3 📌 26
Preview
Cell state-specific cytoplasmic density controls spindle architecture and scaling - Nature Cell Biology Kletter et al. show that cell state-specific cytoplasmic density controls spindle architecture and scaling in neural differentiation, suggesting that the physical properties of the cytoplasm are a det...

🍹Kletter et al. show that cell state-specific cytoplasmic density controls spindle architecture and scaling in neural differentiation, suggesting that the physical properties of the cytoplasm are a determinant in #organelle size control.
bit.ly/4mhMvsU

02.08.2025 18:54 👍 29 🔁 11 💬 2 📌 0

But imo the professional writer pitched in the article is instead promoting the idea of a factory line where the lab provides the data and figures and the writer writes. This to me isn’t collaborative and harms the scientific development of the lab as well as the paper even if the prose has improved

10.07.2025 12:40 👍 3 🔁 0 💬 1 📌 0

Absolutely! Collaborative writing like collaborative science benefits from diversity of perspective.

I don’t think that anyone is objecting to the idea of students or postdocs helping finish write a manuscript or tighten up a grant 1/2

10.07.2025 12:38 👍 3 🔁 0 💬 1 📌 0

My worry is that there is an intimate link between clarity of expression and thought that is important for both communication as well as for us to refine our ideas. The article refers to a writer “squeezing out explanations of figures and data” which belies a worrisome divorce in this central tenet

10.07.2025 12:05 👍 4 🔁 0 💬 1 📌 0
Post image Post image

🚨Join us! We're soon opening 3 postdoctoral positions in #AIDrivenBiology. Seeking biologists (especially microbiology and infection biology), computer scientists, and microscopy developers. Ideal candidates are those eager to use or develop next-gen tech for cell biology. Get in touch (DM/email)

10.07.2025 08:34 👍 50 🔁 31 💬 1 📌 0
A picture of 3 rows of people on steps at the MRC LMB. From left to right - top row: Akaash, Vic, Lara - Middle row: Kerrie, Manu, Paddy - bottom row: Meg  and Julie

A picture of 3 rows of people on steps at the MRC LMB. From left to right - top row: Akaash, Vic, Lara - Middle row: Kerrie, Manu, Paddy - bottom row: Meg and Julie

🚨 JOB ALERT 🚨
We're hiring a Research Assistant – no PhD needed!
Join us to explore the molecular mechanisms of receptor sorting in endosomes.
Experience in protein expression/purification, cloning & cell culture desired 🧫🔬
Apply now 👉 www.nature.com/naturecareer...

#STEMCareers #ResearchJobs

23.06.2025 13:00 👍 49 🔁 32 💬 1 📌 5
Video thumbnail

Finally here! Our preprint on the MOSAIC, a multimodal adaptive optical microscope enabling non‑invasive in‑vivo imaging from molecules to organisms, is out. MOSAIC captures everything from subcellular dynamics to neural activity in live mice.
www.biorxiv.org/content/10.1...

16.06.2025 21:26 👍 31 🔁 10 💬 0 📌 1

Thanks Simone! Ive also finally gotten around to getting back on science socials again 😅

07.06.2025 17:42 👍 2 🔁 0 💬 0 📌 0