Alicia Alonso de la Vega

Tons of cool scientific discussions and better company at the Downward lab retreat 2025 @juliandownward.bsky.social @molinaarcas.bsky.social

Congrats Debbie! ✨ so happy for you

Lung Cancer Prevention Laboratory Pioneering research in lung cancer to improve diagnosis, treatment and prevention

I am excited to announce that my laboratory @ucl.ac.uk is now open!

We are hiring so please contact us if you are interested.

www.caswelllaboratory.com

Dysfunctional CD11c−CD21− extrafollicular memory B cells are enriched in the periphery and tumors of patients with cancer Tumor-associated extrafollicular B cells are phenotypically, locationally, and functionally distinct from germinal center–dependent memory B cells.

Tumor-associated extrafollicular B cells are phenotypically, locationally, and functionally distinct from germinal center–dependent memory B cells
@bcellbruno.bsky.social @ancasey.bsky.social
www.science.org/doi/10.1126/...

Human-correlated genetic models identify precision therapy for liver cancer - Nature As proof of principle, an analysis using a suite of human-aligned immunocompetent mouse models of hepatocellular carcinoma identifies a promising therapeutic candidate, cladribine, which acts in ...

A little MYC goes a long way!
Check out this absolute tour de force from colleagues Miryam Müller, Stephanie May, Tom Bird and team who assembled an compendium of liver cancer mouse models mirroring a spectrum of human HCC subtypes:
www.nature.com/articles/s41...

For RAS enthusiasts, register to the 2nd Targeting RAS symposium! Amazing speakers in beautiful Salamanca #RAS #KRAS

Lung cancer cells can go ‘off grid’ Researchers from the Francis Crick Institute have found that some particularly aggressive lung cancer cells can develop their own electric network, like that seen in the body’s nervous system. This un...

Crick researchers have found that certain aggressive lung cancer cells can develop their own electric network, similar to the body’s nervous system.

This can allow tumour cells to go ‘off grid,’ making them harder to treat.
www.crick.ac.uk/news/2025-02...